Navigation Links
Nanosponge drug delivery system more effective than direct injection
Date:6/2/2010

rticles and for attaching the linkers, which are made from peptides, relatively small biological molecules built by linking amino acids. "Many other drug delivery systems require complicated chemistry that will be difficult to scale up for commercial production, but we have continually kept this in mind," Harth says.

The targeting peptide used in the animal studies was developed by the Hallahan laboratory, which also tested the system's effectiveness in tumor-bearing mice. The peptide used in the study is one that selectively binds to tumors that have been treated with radiation.

The drug used for the animal studies was paclitaxel (the generic name of the drug Taxol) that is used in cancer chemotherapy. The researchers recorded the response of two different tumor types slow-growing human breast cancer and fast-acting mouse glioma to single injections. In both cases they found that it increased the death of cancer cells and delayed tumor growth "in a manner superior to know chemotherapy approaches."

The next step is to perform an experiment with repeated injections to see if the nanosponge system can stop and reverse tumor growth. Harth is also planning to perform the more comprehensive toxicity studies on her nanoparticle delivery system that are required before it can be used in clinical trials.


'/>"/>

Contact: David F. Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. A New Firefox Add-on Revolutionizes the Delivery of Discounts for Online Shoppers
2. Drug now used to treat erectile dysfuncton may enhance delivery of herceptin to certain brain tumors
3. FreshDirect Celebrates Nurse Appreciation Week with Delivery of Complimentary 4-Minute Meals for Nurses at Hospitals in Westchester and Greenwich, CT
4. New Nasal Drug Delivery Device for Chronic Sinusitis Patients Now Available from ASL Pharmacy
5. Magnetic Fields Concentrate Drug Delivery
6. Panel questions VBAC bans, advocates expanded delivery options for women
7. Electronic Health Information Leader Says Physician Practice Redesign is Vital Next Step Towards Safer, More Effective Care Delivery
8. Targeted delivery of losartan reduces liver inflammation and scarring
9. Gourmet Diet Delivery Unites with First Lady's Battle Against Obesity The Fresh Diet Begins Delivering Meals to DC
10. GE Healthcare, Intel and Mayo Clinic explore new models of health care delivery
11. Launch of On Time Air Filters: Home Air Filter Delivery Service Helps Homeowners Replace All-Important Home HVAC Filters On Time
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanosponge drug delivery system more effective than direct injection
(Date:7/22/2014)... 22, 2014 SkillSurvey Inc., the ... help employers make better hiring decisions, will be ... improve the engagement and retention of contingent workers ... IMAGE 2014 Conference being held in Orlando, Florida ... a case study featuring Metro Health, a hospital ...
(Date:7/22/2014)... The “Human Insulin Market by Product Type ... Human Insulin (Rapid Acting, Long Acting, Premixed)], by ... - Forecast to 2019” provides a detailed overview ... market trends, and strategies impacting the global human ... of the revenue and share analysis. , Browse ...
(Date:7/22/2014)... Dr. Larry Kaplan and concerned leading dentists ... Experts Benefit Dinner May 30, in St. Petersburg, FL. ... funds for the Improving Youth Literacy Campaign, in support ... The funds raised are providing hundreds of thousands of ... break the cycle of poverty. , Notables who ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 The ... insight into the specific market segment called disposable ... segment within the global healthcare equipment and supplies ... with needles, prefilled syringes, disposable medical catheters, wound ... gloves, adult incontinence products, blood glucose test strips, ...
(Date:7/22/2014)... Cloud+MD Office 2.0 is ... of medical software and services, designed by experienced ... produces “Actionable Information” to help Independent Physician Practices, ... Billing Services optimize a wide range of business ... Efficiency, Noticeable Cost Reductions and Better Patient Care. ...
Breaking Medicine News(10 mins):Health News:SkillSurvey to Present Research on Contingent Workers at National Association for Health Care Recruitment IMAGE 2014 Conference 2Health News:Human Insulin Market Worth $42 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Human Insulin Market Worth $42 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Human Insulin Market Worth $42 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Human Insulin Market Worth $42 Billion by 2019 - New Report by MarketsandMarkets 5Health News:Dr. Larry Kaplan Successfully Attacks a Major Source of Economic Destruction in the Battle Against Illiteracy and Poverty 2Health News:Dr. Larry Kaplan Successfully Attacks a Major Source of Economic Destruction in the Battle Against Illiteracy and Poverty 3Health News:Growth of Disposable Medical Supplies Market to 2019 Report Available at RnRMarketResearch.com 2Health News:Growth of Disposable Medical Supplies Market to 2019 Report Available at RnRMarketResearch.com 3Health News:Growth of Disposable Medical Supplies Market to 2019 Report Available at RnRMarketResearch.com 4Health News:Growth of Disposable Medical Supplies Market to 2019 Report Available at RnRMarketResearch.com 5Health News:Cloud-MD Software will soon Receive MU2 Certification 2
... joint becomes inflamed. Treatment is often difficult and recovery ... the pain of this common condition. ,Now, an ... with extracorporeal shock wave therapy. During the therapy, ultrasound ... takes two to three 20-minute shock wave treatments to ...
... located at the base of the hair follicle. Hair ... In many people with hair loss, however, // the ... of abnormal follicles entering longer resting phases and producing ... University of Pennsylvania School of Medicine have isolated stem ...
... say there could be a new way to help prevent ... // increase high-density lipoprotein levels, also known as good cholesterol. ... for heart disease. They are commonly used to lower low-density ... target is a low level of good cholesterol. In fact, ...
... Toronto conducted a study to examine whether current procedures ... antibiotics // unnecessarily. Out of an estimated 6.7 million ... Doctors also researched the use of throat cultures and ... who were prompted to seek medical help for their ...
... attention deficit/hyperactivity disorder (ADHD) affects up to 12 percent of ... increased attention problems at age 7 among kids was seen ... toddlers.The study tracked the number of hours kids watched television ... two hours of television a day. Three-year-olds watched about three ...
... warnings from the Food and Drug Administration may leave ... what they claim.// ,Some of the products ... Blocker, and Zone Fat Blocker.Many of these supplements claim ... consumers to lose weight without making any lifestyle changes. ...
Cached Medicine News:
(Date:7/22/2014)... Fla. , July 22, 2014  Neurotrope Bioscience, ... signed a world-wide, exclusive license agreement with the Icahn ... ( Mount Sinai ) to utilize ... of Bryostatin-1 in the treatment of Niemann-Pick Type C ... are afflicted with Alzheimer-like symptoms. The license also covers ...
(Date:7/22/2014)... , July 22, 2014  ConvaTec, a privately-held ... Nigel Clerkin has been appointed chief financial officer ... Mr. Clerkin was previously executive vice president and chief ... -based biotechnology company.  Mr. Clerkin was part of ... at Elan, culminating in its sale to Perrigo, a ...
(Date:7/22/2014)... The steady decline of pharmaceutical sales ... rep-friendly specialties, according to the spring 2014 AccessMonitor™ ... ZS Associates.      AccessMonitor™ aggregates sales-call ... teams. The report examines how often approximately 325,000 ... sales reps who visit their offices. ...
Breaking Medicine Technology:Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 2Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 3Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 4Neurotrope Enters Collaborative Agreement with Icahn School of Medicine at Mount Sinai for use of Bryostatin-1 in the Treatment of Niemann-Pick Disease Type C 5ConvaTec Names Nigel Clerkin Chief Financial Officer 2Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 2Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 3Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 4Even traditionally rep-friendly specialists will see fewer pharmaceutical sales reps this year, according to ZS Associates 5
... ALIF Allograft is processed from 100% cortical ... support. The graft is machined with a ... to graft migration. The intermedulary canal accommodates ... ALIF Allografts contain a relief orientation in ...
Lumbar Allograft with Osteoactive advantage. Promotes bone formation and faster incorporation. Derived from the proven technology behind Grafton DBM. Maintains structural integrity and strength....
Williams Micro Discectomy Instruments are designed to be used in the microsurgical treatment of herniated disks....
... Anteater Titanium Microdiscectomy System offers strength ... surgery. The boss anteater titanium microdiscectomy ... intervertebral discs provides for less invasive ... retractor is designed to provide low ...
Medicine Products: