Navigation Links
Nanoscale 'stealth' probe slides into cell walls seamlessly, say Stanford engineers
Date:4/1/2010

ing suction, we can use high voltage to puncture holes in their membranes, both of which are fairly destructive," he said. "Many of the cells don't survive." That limits the duration of any observations, particularly electrical measurements of cell function.

The key to the probe's easy insertion and the membrane's desire to retain it is that Melosh and Almquist based its design on a type of protein naturally found in cell walls that acts as a gatekeeper, controlling which molecules are allowed in or out.

A cell membrane is essentially a walled fortress. Within the wall itself is a water-repellant, or hydrophobic, zone. Since almost all molecules in a living being are water soluble, the hydrophobic region acts as a barrier to keep the molecules from slipping through the cell wall. The only way in or out is via the specialized proteins that form bridges across the membrane.

Those "transmembrane" protein gateways match the architecture of the membrane, with a hydrophobic center section bounded by two water soluble, or hydrophilic, layers.

"What we have done is make an inorganic version of one of those membrane proteins, which sits in the membrane without disrupting it," Melosh said. "Now we can envision using it for doing our own gate keeping."

To build their probe, Melosh and Almquist appropriated nanofabrication methods from the semiconductor industry to make tiny silicon posts, the tips of which they coated with three thin layers of metal a layer of gold between two of chromium to match the sandwich structure of the membrane. They then coated the gold band with carbon molecules to render it hydrophobic; the chromium bands are naturally hydrophilic.

"Getting that hydrophobic band just a few nanometers in thickness was an incredible technical challenge," Melosh said. Applying such a thin layer to the tip of a probe only 200 nanometers in diameter was impossible using existing methods, so he and Almquist devised
'/>"/>

Contact: Louis Bergeron
louisb3@stanford.edu
650-725-1944
Stanford University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. NASA selects DNA Medicine Institutes Nanoscale Diagnostics Technology for Phase II SBIR
2. Fluorescent probes light up cancerous tumors
3. Gen-Probe to Webcast Presentation at the 21st Annual Piper Jaffray Health Care Conference Today
4. Palo Alto Networks Next-Generation Firewalls Deliver High-Performance Network Protection for Shinshu University
5. Mathematical innovation turns blood draw into information gold mine in Stanford study
6. Interleukin Genetics, Inc. and Stanford University Report Genetic Test Improves Weight Loss Success With Diets
7. Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California
8. AIDS Research Alliance Gains Exclusive Rights To New Technology from Stanford University
9. Stanford scientists identify protein that keeps stem cells poised for action
10. Muscle cell infusion shown to strengthen sphincters in animals in Stanford study
11. Artists, Product Designers, Printing Gurus, Game Developers, Manufacturing Engineers Will Converge at RAPID 2010/3D IMAGING Conference/Expo, May 18-20 in LA
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanoscale 'stealth' probe slides into cell walls seamlessly, say Stanford engineers
(Date:7/11/2014)... (PRWEB) July 11, 2014 Utilizing the ... own, Dr. William Koenig, has topped a record number ... he has performed over 400 successful procedures without the ... Koenig is well known across the country for his ... safety record has long been the foundation for numerous ...
(Date:7/11/2014)... July 11, 2014 (HealthDay News) -- U.S. health officials ... were exposed to live anthrax during a safety mishap ... Control and Prevention officials have announced a moratorium on ... high-level government labs. In a report issued Friday, ... to make sure a similar incident doesn,t occur again. ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 According to ... & Application Market by Communication Technology (ZigBee, Z-Wave, Bluetooth, ... Electronics, Industrial, Automotive & Transportation, Agriculture) & Geography - ... value of Internet of Things market was worth $1029.5 ... Billion by 2020, at an estimated CAGR of 4.08% ...
(Date:7/11/2014)... Toledo, Ohio (PRWEB) July 11, 2014 ... (Morgenson 7/10/14) and FiercePharma (Weintraub 7/11/14), a significant number ... in blood sugar, abdominal issues and even death from ... exposed. , According to the Times report , ... events in 2013 reported by patients was almost 14% ...
(Date:7/11/2014)... NY (PRWEB) July 11, 2014 The ... the five years to 2014 on the heels of ... 2010 prompted farmers to dedicate a larger share of ... production. More specifically, the regulations required the mixing of ... expanding biofuel production in the United States created a ...
Breaking Medicine News(10 mins):Health News:Rochester Surgeon Hits Milestone with Keller Funnel 2Health News:CDC Issues Tough Report on Anthrax Scare 2Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Internet of Things Technology & Application Market Worth $1423.09 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Acthar’s Deadly Adverse Events Revealed 2Health News:Acthar’s Deadly Adverse Events Revealed 3Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 2Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 3
... announced that it has raised over $20 million in ... raised approximately $15 million through equity contributions by existing ... Intel Capital, Saudi Venture Development Company, Unilever Technology Ventures ... as a new investor. On top of the ...
... Biomedical Corporation (TSX: RBM, OTCBB: RPBIF) announced that ... of the Year by LifeSciences British Columbia. This ... to recognize an organization that has made outstanding ... sciences industry and to increase public awareness and ...
... Until now, people could expect to need reading glasses ... an aging process called presbyopia. LASIK, a proven technique ... for presbyopia. But today, according to results from a ... M.D., and published in the Journal of Refractive Surgery, ...
... Information Technology CommunitySAN DIEGO and MCLEAN, Va., March 9 ... ) today announced that Federal Computer Week ... leaders who played pivotal roles in the federal information ... individuals from government, industry and academia. Shea and ...
... Bring Specialists Together in Local Meetings and Online; and Help ... the need for long term care insurance grows, agents and ... and with a high level of professionalism. And the public ... area. A new organization will aid the pros as well ...
... KABC-TV Anchor Phillip PalmerLOS ANGELES, March 9 A ... determined the life-or-death fate of kidney patients applying for ... March 12. Produced by Lori Hartwell and the Renal ... transplant recipients R. Martin Klein and Dale Wade Davis, ...
Cached Medicine News:Health News:Surface Logix Raises $20 Million in Financing and Starts Phase 2b Clinical Trial of SLx-4090 in Dyslipidemia and Diabetes 2Health News:Response Biomedical Named Medical Device Company of the Year by LifeSciences British Columbia 2Health News:SAIC's K. Stuart Shea Named Federal 100 Winner by Federal Computer Week 2Health News:Industry Leaders Applaud Formation of Long Term Care Insurance Guild 2Health News:Industry Leaders Applaud Formation of Long Term Care Insurance Guild 3Health News:'Who Lives?' to Open at Pico Playhouse on World Kidney Day This Thursday 2
(Date:7/11/2014)... Research and Markets has announced the addition ... Industry Report 2014" report to their offering. ... And Chinese Medical X-Ray Film Industry Report 2014 is ... of the Global medical X-ray film industry with a ... a basic overview of the industry including definitions, classifications, ...
(Date:7/11/2014)... 11, 2014  Kindred Hospital Houston Northwest, with ... opening of its new outpatient wound healing center.  ... people with chronic, hard to heal wounds. Chronic ... to amputation, lower leg wounds related to blood ... and traumatic injury wounds which are complex and ...
(Date:7/11/2014)... According to a new market ... (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) - Global ... the global endoscopy devices market was valued at USD ... at a CAGR of 6.8% from 2013 to 2019, ... in 2019. Browse the full Endoscopy Devices Market ...
Breaking Medicine Technology:Global and Chinese Medical X-ray Film Industry Report 2014 2Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6
... Findings Show Survival Improvement with Lower Doses ... and other,Drugs in Newly Diagnosed Myeloma -, ... -- The,International Myeloma Foundation (IMF) - supporting ... myeloma patients,families, researchers and physicians - today ...
... April 5, 2007-- Stent thrombosis,restenosis and lifelong prescriptions. ... used as part of their heart,operations may be ... than medical experts have ever publicly acknowledged. Recent,articles ... drug-eluting stents continue to take blood thinners, they,could ...
Cached Medicine Technology:The International Myeloma Foundation Says New Clinical Trial,Results Could Improve Survival While Reducing Side Effects For Many,Patients 2The International Myeloma Foundation Says New Clinical Trial,Results Could Improve Survival While Reducing Side Effects For Many,Patients 3New Cardioprotective Drug Could Provide Boost For Post-Bypass,Surgery Heart Health 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: