Navigation Links
Nanoparticles to probe mystery sperm defects behind infertility
Date:11/15/2013

A way of using nanoparticles to investigate the mechanisms underlying 'mystery' cases of infertility has been developed by scientists at Oxford University.

The technique, published in Nanomedicine: Nanotechnology, Biology and Medicine, could eventually help researchers to discover the causes behind cases of unexplained infertility and develop treatments for affected couples. The method involves loading porous silica nanoparticle 'envelopes' with compounds to identify, diagnose or treat the causes of infertility.

The researchers demonstrated that the nanoparticles could be attached to boar sperm with no detrimental effects on their function.

'An attractive feature of nanoparticles is that they are like an empty envelope that can be loaded with a variety of compounds and inserted into cells,' says Dr Natalia Barkalina, lead author of the study from the Nuffield Department of Obstetrics and Gynaecology at Oxford University. 'The nanoparticles we use don't appear to interfere with the sperm, making them a perfect delivery vessel.

'We will start with compounds to investigate the biology of infertility, and within a few years may be able to explain or even diagnose rare cases in patients. In future we could even deliver treatments in a similar way.'

Sperm are difficult to study due to their small size, unusual shape and short lifetime outside of the body. Yet this is a vital part of infertility research, as senior author Dr Kevin Coward explains: 'To discover the causes of infertility, we need to investigate sperm to see where the problems start. Previous methods involved complicated procedures in animals and introduced months of delays before the sperm could be used.

'Now, we can simply expose sperm to nanoparticles in a petri dish. It's so simple that it can all be done quickly enough for the sperm to survive perfectly unharmed.'

The team, based at the Institute of Reproductive Sciences, used bo
'/>"/>

Contact: University of Oxford Press Office
press.office@admin.ox.ac.uk
44-018-652-80528
University of Oxford
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Shape of nanoparticles points the way toward more targeted drugs
2. New gene delivery method: magnetic nanoparticles
3. Shape-shifting nanoparticles flip from sphere to net in response to tumor signal
4. Mayo Clinic: How gold nanoparticles can help fight ovarian cancer
5. New technique can help nanoparticles deliver drug treatments
6. Nanoparticles loaded with bee venom kill HIV
7. Researchers show that lipid nanoparticles are ideal for delivering genes and drugs
8. New electrically-conductive polymer nanoparticles can generate heat to kill colorectal cancer cells
9. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
10. Nanoparticles detect biochemistry of inflammation
11. Improved nanoparticles deliver drugs into brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanoparticles to probe mystery sperm defects behind infertility
(Date:11/27/2014)... 27, 2014 "As a nurse I ... effects of urinary incontinence," said an inventor from Whiting, ... this specialized accessory to prevent leakage and keep them ... absorb urine leakage. This prevents stains on pants, skirts ... The pad ensures that the individual has time to ...
(Date:11/27/2014)... Most babies and young children don,t need medicines if ... Administration says. Over-the-counter (OTC) cold and cough medicine ... because they could cause serious and potentially deadly side ... three colds a year, but children get them more ... to give them pain relievers, decongestants and other medicines, ...
(Date:11/27/2014)... In order to enable people to adapt ... an easy way to avoid touching a toilet seat and/or ... a prototype of the patent-pending Toilet Tamer, a device that ... and/or lid in a more sanitary manner. It avoids direct ... Overall, it promotes good hygiene and peace of mind. The ...
(Date:11/27/2014)... (PRWEB) November 27, 2014 Now that ... season has officially launched, Emassagechair.com has announced ... Monday Discount Event. , Negotiating on behalf of ... top massage chair brands, Emassagechair.com has generated significant buzz ... deals and biggest discounts yet. , Shoppers are excited ...
(Date:11/27/2014)... 2014 VogueQueen.com is making every effort ... across the world. As the premier online supplier of ... proud to release a huge selection of sexy prom ... it is also providing many beautiful styles in its ... at discounted prices. , “VogueQueen.com hopes to provide ...
Breaking Medicine News(10 mins):Health News:Steer Clear of Cold Meds for Babies, FDA Advises 2Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 2Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 3Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 4Health News:A New Collection of Sexy Prom Dresses Has Been Released by the Reliable Online Supplier VogueQueen.com 2
... June 3 OrthoSynetics(TM), the largest,provider of business ... two new members to its IT team. Allen ... and David D,Entremont has,been hired as senior network ... facet of our organization, and,the addition of these ...
... be issued under second round of Critical Challenges ... The Michael J. Fox,Foundation for Parkinson,s Research ... test non-invasive imaging technologies that would allow,scientists to ... the living brain. Such techniques hold potential to,serve ...
... Public Relations, WALTHAM, Mass., June 3 ... relations agencies, today announced,that its co-founders, Steve and ... J. Malloy Crystal Bell Lifetime Achievement Award last ... Ringer Awards., (Logo: http://www.newscom.com/cgi-bin/prnh/20080603/NETU111 ), ...
... Growths are able to maintain significant testosterone ... June 3 (HealthDay News) -- U.S. researchers ... prostate cancer becomes resistant to androgen-deprivation therapy, ... promotes prostate cancer growth. , Androgen therapy, ...
... seen in those who had relatives with disease, study finds ... that increases the risk of developing colorectal cancer also seems ... study indicates. , People with colorectal cancer who had close ... die or to have a recurrence after treatment, according to ...
... at Cold Spring Harbor Laboratory (CSHL) have taken the ... a newly published paper, they confirm that a gene ... in living mice that its deletion, inactivation or loss ... cancer closely related to common human epithelial cancers of ...
Cached Medicine News:Health News:OrthoSynetics(TM) Adds Two Experienced Pros to IT Team 2Health News:Michael J. Fox Foundation for Parkinson's Research Commits up to $2 million to Visualize Alpha-Synuclein Protein in the Brain 2Health News:Michael J. Fox Foundation for Parkinson's Research Commits up to $2 million to Visualize Alpha-Synuclein Protein in the Brain 3Health News:Steve and Paula Mae Schwartz Honored With Publicity Club of New England's Crystal Bell Award 2Health News:Androgen Production Continues in Prostate Cancer Tumors 2Health News:Family History Might Improve Odds Against Colon Cancer 2Health News:CSHL scientists trace causal link between a tumor suppressor gene and liver cancer 2Health News:CSHL scientists trace causal link between a tumor suppressor gene and liver cancer 3
(Date:11/26/2014)... ALISO VIEJO, Calif. , Nov. 26, 2014 ... today announced that the U.S. Food and Drug ... to its New Drug Application (NDA) for AVP-825. ... of low-dose sumatriptan powder delivered intranasally utilizing a ... In the Complete Response letter, and consistent with ...
(Date:11/26/2014)... Scott Steiger lives in St. Louis ... for the past 20 years, he,s traveled extensively and prior to ... to six of the seven continents. Travel is a big part ... Photo - http://photos.prnewswire.com/prnh/20141126/161077 So when he ... idea of what,s required. His latest creation is the ...
(Date:11/26/2014)... 26, 2014 Zynerba Pharmaceuticals , Inc., ... innovative transdermal synthetic cannabinoid treatments, today announced that the ... Healthcare Conference 2014. The conference will be held December ... New York . Zynerba,s Chairman and ... pm on Tuesday, December 2. To listen ...
Breaking Medicine Technology:Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 2Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 4Steiger Has Created the First Pill Case Specifically Designed For Travel 2Zynerba Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2014 2
... Dec. 9 BrainLAB, a manufacturer of software-driven ... St. Luke,s Hospital in Cedar Rapids, Iowa, has acquired ... Digital Lightbox© with TraumaCad(TM), a pre-operative planning and digital ... North America to acquire this technologically advanced duo. ...
... , INDIANAPOLIS, Dec. 9 tw telecom ... voice, Internet and data networking solutions for businesses in Indianapolis ... has selected the company to provide advanced voice, data and ... Indiana. Indiana Blood Center will also utilize tw telecom, ...
Cached Medicine Technology:St. Luke's Hospital Acquires Pioneering Technology From BrainLAB 2St. Luke's Hospital Acquires Pioneering Technology From BrainLAB 3Indiana Blood Center Taps tw telecom for Data, Internet and IP Telephony Services 2
Shoulder rasp...
Arthrex has the most extensive offering of arthroscopic suture passing instruments,available anywhere in the world. We have speci? cally designed the function of our,instruments to work hand in hand ...
85 left angled suture passer....
45 right angled suture passer....
Medicine Products: