Navigation Links
Nanoparticles loaded with bee venom kill HIV
Date:3/8/2013

nothing to stop initial infection, and some strains of the virus have found ways around these drugs and reproduce anyway.

"We are attacking an inherent physical property of HIV," Hood says. "Theoretically, there isn't any way for the virus to adapt to that. The virus has to have a protective coat, a double-layered membrane that covers the virus."

Beyond prevention in the form of a vaginal gel, Hood also sees potential for using nanoparticles with melittin as therapy for existing HIV infections, especially those that are drug-resistant. The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream.

"The basic particle that we are using in these experiments was developed many years ago as an artificial blood product," Hood says. "It didn't work very well for delivering oxygen, but it circulates safely in the body and gives us a nice platform that we can adapt to fight different kinds of infections."

Since melittin attacks double-layered membranes indiscriminately, this concept is not limited to HIV. Many viruses, including hepatitis B and C, rely on the same kind of protective envelope and would be vulnerable to melittin-loaded nanoparticles.

While this particular paper does not address contraception, Hood says the gel easily could be adapted to target sperm as well as HIV. But in some cases people may only want the HIV protection.

"We also are looking at this for couples where only one of the partners has HIV, and they want to have a baby," Hood says. "These particles by themselves are actually very safe for sperm, for the same reason they are safe for vaginal cells."

While this work was done in cells in a laboratory environment, Hood and his colleagues say the nanoparticles are easy to manufacture in large enough quantities to supply them for future clinical trials.


'/>"/>

Contact: Julia Evangelou Strait
straitj@wustl.edu
314-286-0141
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Researchers show that lipid nanoparticles are ideal for delivering genes and drugs
2. New electrically-conductive polymer nanoparticles can generate heat to kill colorectal cancer cells
3. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
4. Nanoparticles detect biochemistry of inflammation
5. Improved nanoparticles deliver drugs into brain
6. UCSB scientists examine effects of manufactured nanoparticles on soybean crops
7. New nanoparticles shrink tumors in mice
8. Researchers find gold nanoparticles capable of unzipping DNA
9. Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment
10. Applied nanobiomedicine: Exploiting nanoparticles to hunt for hidden cancer cells
11. Launch of CouponCanny.com Pre-loaded with Coupon Codes and Deals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanoparticles loaded with bee venom kill HIV
(Date:5/22/2015)... CA (PRWEB) May 22, 2015 ... Sunset Plaza Dental announces that they are now ... restorative and other dental treatments. At consultations, patients ... them. Questions regarding what certain treatments can achieve ... be covered during this initial appointment. If treatments ...
(Date:5/22/2015)... 22, 2015 A Phase 3 ... American Society of Clinical Oncology (ASCO)’s annual meeting ... rates for those patients who received bevacizumab in ... pemetrexed/cisplatin. Bevacizumab (Avastin® Genentech, Inc.) is an antibody ... is already routinely used to treat many other ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 In an ... Parker and Sons is offering to donate $5 dollars ... an AC unit or water softening system. Customers have ... Parker and Sons gets business; and the Special Olympics ... The Special Olympics helps over 4.4 million athletes, and ...
(Date:5/22/2015)... A new program for the "In America" television ... Physical Therapy. , James Earl Jones will host ... physical therapy and discusses how the exercises can decrease ... of ailments and injuries. Physical therapists work with ... enhances daily activities such as house cleaning and shopping, ...
(Date:5/22/2015)... 22, 2015 Yisrayl Hawkins, Pastor and Overseer ... a new letter calling on religious leaders to make changes ... was published on his blog, discusses the history of war, ... to stop it. Yisrayl says mankind was created to lead ... in today’s society. , “Yahweh created mankind, according to ...
Breaking Medicine News(10 mins):Health News:West Hollywood Dental Office, Sunset Plaza Dental is Now Offering Complimentary Consultations 2Health News:Mesothelioma Research Organization Excited About Imminent Improvement to Standard of Care 2Health News:Parker and Sons is Proud to Support the Special Olympics with Their Everybody Wins Program 2Health News:Yisrayl Hawkins Calls on All Religions to Wake Up and Make Drastic Changes to End Suffering in New Letter 2
... more attention to choosing the doctor, not the device ... as a safe and long-lasting way to alleviate hip-related ... fails, the problem more often lies with surgical error ... , , Dislocation of the implant was the most common ...
... gene is a key to understanding, and perhaps killing, ... only to reawaken years later, researchers at The University ... the December Journal of Clinical Investigation . , ... ARHI acts as a switch for autophagy, or self-cannibalization, ...
... that Lewy bodies, clumps of aggregated proteins inside ... Parkinson,s disease and other neurodegenerative diseases. , The ... protein recycling and waste disposal, leading to the ... cells? , One possible answer: by breaking a ...
... supplementation was found to be effective in relieving pain ... chronic pancreatitis (CP), reports a new study in ... the pancreas in which patients experience abdominal pain (in ... Pain is the major problem in 90 percent of ...
... from presence of salicylic acid in study participants , , ... key component that gives aspirin its anti-inflammatory and pain-relieving ... own, a new study suggests. , Salicylic acid (SA) ... who had not taken aspirin recently -- especially vegetarians. ...
... organ improved odds, study shows , , WEDNESDAY, Dec. 31 ... donated kidney raised the chances of a successful transplant ... European researchers report. , The study, published in the ... of Medicine , got generally favorable reviews from American ...
Cached Medicine News:Health News:Surgeons Often Are Blamed When Hip Replacements Fail 2Health News:Surgeons Often Are Blamed When Hip Replacements Fail 3Health News:Dormant cancer cells rely on cellular self-cannibalization to survive 2Health News:Toxicity mechanism identified for Parkinson's disease 2Health News:Antioxidants offer pain relief in patients with chronic pancreatitis 2Health News:A Better Method of Kidney Storage 2Health News:A Better Method of Kidney Storage 3
(Date:5/22/2015)... AcelRx Pharmaceuticals, Inc. (Nasdaq: ACRX ), ... commercialization of innovative therapies for the treatment of acute ... officer Howie Rosen will be presenting at ... Tim Morris will be presenting at JMP Securities ... as follows: Jefferies 2015 Healthcare Conference Date: ...
(Date:5/21/2015)... DUBLIN , May 21, 2015 ... has announced the addition of the "North ... & Graft), by Application (Surgical Wound, & Ulcer), ... Forecast to 2019" report to their offering. ... wound care market is estimated to grow at ...
(Date:5/21/2015)... , May 21, 2015  Cardica, Inc. (Nasdaq: ... employee Greg Watson , the company,s vice president of ... the company,s common stock, at a per share exercise price ... The stock option was granted pursuant to Cardica, Inc.,s Inducement ... in May 2015 under Rule 5653(c)(4) of the Nasdaq Global ...
Breaking Medicine Technology:AcelRx Pharmaceuticals to Present at Two Upcoming Investor Conferences In June 2North American Active Wound Care Market 2015-2019 with Smith and Nephew, Molyncke HealthCare & ConvaTec Dominating 2Cardica Announces New Employment Inducement Grant 2
... 1, 2011 Every year thousands of children are hospitalized ... for them. (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO) Teens share ... by colorful pills that look like candy. ... how you can prevent harm by locking your medicine up. ...
... N.J., Nov. 1, 2011 Quest Diagnostics Incorporated (NYSE: ... diagnostic testing, information and services, today announced the CE ... & RSV Direct test on the 3M™ Integrated Cycler. ... uses a proprietary technique to eliminate nucleic-acid sample extraction, ...
Cached Medicine Technology:Quest Diagnostics Announces Launch of Simplexa™ Direct Test for Influenza and Respiratory Viruses in Europe 2Quest Diagnostics Announces Launch of Simplexa™ Direct Test for Influenza and Respiratory Viruses in Europe 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: