Navigation Links
Nanoparticles + light = dead tumor cells
Date:7/29/2008

July 25, 2008 -- Medical physicists at the University of Virginia have created a novel way to kill tumor cells using nanoparticles and light. The technique, devised by Wensha Yang, an instructor in radiation oncology at the University of Virginia, and colleagues Ke Sheng, Paul W. Read, James M. Larner, and Brian P. Helmke, employs quantum dots. Quantum dots are semiconductor nanostructures, 25 billionths of a meter in diameter, which can confine electrons in three dimensions and emit light when exposed to ultraviolet radiation.

Yang and his colleagues realized that quantum dots also give off light when exposed to megavoltage x-rays, such as those used in cancer radiotherapy. That property, the scientists realized, makes quantum dots an ideal mediator in therapies employing light-activated compounds to treat cancer.

A compound called Photofrin is the only photosensitizer currently approved by the FDA. Photofrin is absorbed by cancer cells and, upon exposure to light, becomes active and kills cells. It is currently used to treat certain kinds of shallowly located tumors, but Yang and his colleagues realized that combing Photofrin with quantum dots could create an efficient method to kill even deeply seated cancer cells. Upon exposure to high doses of radiation, the dots become luminescent and emit light; that light triggers the cancer-killing activity of the Photofrin. In theory, the process, which so far has been studied only in cancer cells grown in culture, could work on tumors located too deep within the body to be reached by an external light source.

To prevent normal tissues from being affected by the treatment, the toxicity of the quantum dot-Photofrin conjugate is only activated when radiation is applied. Also, the area to be treated is targeted with conformal radiation, which is delivered with high precision within the three-dimensional contours of the tumor, with minimal spillover to surrounding healthy tissues. As a result
'/>"/>

Contact: Jason Bardi
jbardi@aip.org
301-209-3091
American Institute of Physics
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Using magenetic nanoparticles to combat cancer
2. Nanoparticles aid bone growth
3. Magnetic nanoparticles: Suitable for cancer therapy?
4. Brown chemists create cancer-detecting nanoparticles
5. Iowa State University researcher looks to use nanoparticles for food safety
6. Symposium to explore role nanoparticles may play in disease
7. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
8. Elekta Family of Companies to Highlight Cancer Treatment Solutions at 2008 AAPM Annual Meeting
9. Survey Highlights Physician Motivations for Working Locum Tenens Jobs
10. New approach sheds light on ways Circadian disruption affects human health
11. Democratic National Committee: Democrats Highlight McCains Plan to Privatize Social Security in New Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... York, NY (PRWEB) December 20, 2014 ... the healthcare sector have benefited the Massage Services ... the discretionary characteristics of industry products, the anticipated 1.0% ... five-year period has provided consumers with the means to ... that have received a massage in a given year ...
(Date:12/20/2014)... The print component of Healthy Aging is ... approximately 160,000 copies and an estimated readership of 420,000. ... social media strategy and across a network of top ... version of the campaign, click here . , ... ladies of CTV’s The Social. Lainey Lui, Melissa ...
(Date:12/20/2014)... 2014 The Doctor’s Office Urgent Care of ... part of a decade. They’ve treated over 40,000 patients ... healthcare alternative to the Paramus area. , ... additions to their staff of top-notch board certified physicians: Christine ... These new doctors will work tirelessly to carry ...
(Date:12/20/2014)... (PRWEB) December 20, 2014 Atore, Inc, ... company just launched first birthday focused portal on December ... BIRTHDAY MESSAGE” launched in both US and Japan. , ... MESSAGE : http://merrybirthday.net/message/ , MERRY BIRTHDAY MESSAGE ... birthday around the world. , Features, Choose from thousands ...
(Date:12/20/2014)... 2014 Developers of FCPX ... new plugin for Final Cut Pro X entitled TranSlice ... 5 allows users to create hand drawn text animations ... Austin, CEO of Pixel Film Studios. “TranSlice Volume 5 ... maintaining an easy to use interface.” , TranSlice Volume ...
Breaking Medicine News(10 mins):Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:The ladies of The Social urge Canadian women to put themselves first over the holiday season and into the new year in Mediaplanet’s “Women’s Health” campaign 2Health News:The Doctor's Office Urgent Care Adds 3 New Physicians to Their Growing Medical Team 2Health News:Atore, Inc. Releasing the First Birthday Portal 2Health News:Pixel Film Studios released a new transition entitled TranSlice Volume 5 exclusively for Final Cut Pro X 2
... that the scents of peppermint or cinnamon could make the ... for long stretches of time makes the drivers of the ... drivers who participated in the study under the conditions of ... control. The odors were added to the air inside the ...
... having fractures, are often routinely prescribed vitamin D and supplemental// ... light the fact that this may not be true. Calcium ... in the elderly people. ,The study had looked into ... people were mobile before they had a low trauma fracture. ...
... risk factor for multiple sclerosis. New study shows that ... suffering from multiple sclerosis. ,In a research done ... had been able to associate habitual smoking with rapid ... study comprising of 201 cases of multiple sclerosis and ...
... that it is possible to generate insulin from brain stem ... was given to patient suffering from type 1 diabetes mellitus, ... where there is availability of insulin, even there remains a ... such is inability of the patient to synthesize insulin in ...
... journal cancer Research, tobacco smoke have been linked with the ... 2 is a cellular protein that had been related to ... been related to rise in production of two proteins that ... lead to the production of the chemical Cox 2. ...
... that intake of calcium supplements over the years can ... of colon cancer.// ,Calcium supplements can reduce ... in colon. Calcium has chemo protective properties that can ... study was in a trial, which observed 930 patients ...
Cached Medicine News:
(Date:12/19/2014)... , Dec. 19, 2014 Breckenridge Pharmaceutical, Inc. ... agreement with MSN Laboratories Pvt. Ltd. ( Hyderabad, ... to commercialize several new ANDAs.  Under the terms of ... products exclusively to Breckenridge for the U.S. market, and ... label.  Breckenridge and MSN have agreed to develop an ...
(Date:12/19/2014)... CARDIFF-BY-THE-SEA, Calif. , Dec. 19, 2014 /PRNewswire/ ...  Sorrento), an oncology company developing new treatments for ... privately-held immuno-oncology company developing proprietary Neukoplast ® ... announced today that the companies have entered into ... CAR-TNK™ (pronounced as "Car-Tank") immunotherapies for the treatment ...
(Date:12/19/2014)... BURLINGTON, Mass. , Dec. 18, 2014  Decision ... the United States will increase ... Growth will be primarily driven by expansion in the ... direct energy devices will be increasingly adopted due to ... launched. Other key findings from Decision Resources ...
Breaking Medicine Technology:Breckenridge Pharmaceutical signs Multi-Product Generic Agreement with MSN Laboratories Pvt. Ltd. 2Sorrento and Conkwest Announce Exclusive Global Collaboration 2Sorrento and Conkwest Announce Exclusive Global Collaboration 3Sorrento and Conkwest Announce Exclusive Global Collaboration 4Sorrento and Conkwest Announce Exclusive Global Collaboration 5U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 2U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 3
... Platelet aggregometers allows to choose the ... Single, dual and four sample units ... or digital computer outputs. In addition ... measure platelet aggregation in platelet-rich-plasma (PRP), ...
... a four channel Platelet Aggregation Profiler with ... assay (Ristocetin cofactor), platelet aggregation and leukocyte ... for the evaluation and confirmation of Heparin ... tests to be run simultaneously and independently. ...
... in achieving improved cost efficiency in ... cut costs is constantly increasing. Optimize ... unnecessary manual interactions. Ensuring security of ... mechanisms like pipetting integrity check. Right ...
Synchron CX3 Delta is a critical care clinical system, providing unparalleled testing speed for the most frequently ordered chemistries-Glucose, BUN, Creatinine, Sodium, Potassium Chloride, CO2 Calci...
Medicine Products: