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Nanoparticle gives antimicrobial ability to fight Listeria longer
Date:12/7/2010

e attracted to each other.

"Both strategies may work together to allow nanoparticles to attract and stabilize nisin," Yao said, "This could substantially reduce the depletion of nisin in various systems."

For practical use, Yao said a solution containing the nanoparticles and free nisin could be sprayed onto foods or included in packaging. The solution requires a balance of free nisin and nisin on the nanoparticles.

"When you reduce the amount of free nisin, it will trigger a release of more nisin from the nanoparticles to re-establish the equilibrium," Yao said. "There will be a substantial amount of nisin preserved to counteract the Listeria."

Using a model, Yao said a sufficient amount of nisin to combat Listeria could be preserved for up to 21 days.

Yao and his colleagues are working on using other food-based antimicrobial peptides and nano-constructs to combat Listeria other foodborne pathogens such as E. coli O157:H7 and salmonella. The U.S. Department of Agriculture and the National Science Foundation funded their research.


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Contact: Brian Wallheimer
bwallhei@purdue.edu
765-496-2050
Purdue University
Source:Eurekalert

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