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Nanomedicine breakthrough could improve chemotherapy for childhood cancer
Date:11/20/2012

enerative diseases.

"If we can restore nitric oxide with these nanoparticles this could have implications for all the illnesses associated with NO deficiencies, including diabetes and neurodegenerative," he says.

The key medical challenge, says Boyer, has been figuring out a way to deliver appropriate doses to specific sites within the body, without provoking an adverse reaction. The Australian Centre for Nanomedicine which crosses science, engineering and medicine is investigating multi-disciplinary solutions.

Boyer says that while biologists have experimented with nitric oxide, mixing it with cancer cells and observing the reactions, "no one has tried to develop a platform to specifically deliver nitric oxide that is, where you want it, when you want it".

The next step is to test the nanoparticle on other cell lines, such as lung and colon cancer cells, and to proceed to in vivo tests. The team also included researchers from the Children's Cancer Institute Australia based at UNSW's Lowy Cancer Research Centre.


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Contact: Steve Offner
s.offner@unsw.edu.au
61-293-851-583
University of New South Wales
Source:Eurekalert

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