Navigation Links
Nanofiber Gel May Spur Growth of New Knee Cartilage
Date:2/4/2010

Animal study reveals new way to repair damage with natural tissue

THURSDAY, Feb. 4 (HealthDay News) -- A new nanofiber gel that promotes cartilage growth in joints has been developed by U.S. researchers.

The material is injected into the damaged joint and stimulates bone marrow stem cells to produce natural cartilage, without the need for expensive growth factors. No current therapy can do this, according to the researchers, from Northwestern University.

Many people -- including amateur and professional athletes and older adults -- have damaged cartilage, which can lead to joint pain and loss of physical function and eventually to osteoarthritis.

"Cartilage does not regenerate in adults. Once you are fully grown, you have all the cartilage you'll ever have," the study's lead author, Ramille N. Shah, an assistant professor of materials science and engineering at the McCormick School of Engineering and Applied Science and assistant professor of orthopedic surgery at the Feinberg School of Medicine, said in a university news release.

The nanoscopic material prompts stem cells in bone marrow to produce cartilage containing type II collagen and repair the damaged joint, the researchers explained. Type II collagen is the major protein in articular cartilage, which is the smooth, white connective tissue that covers the ends of bones where they meet to form joints.

"A procedure called microfracture is the most common technique currently used by doctors, but it tends to produce a cartilage having predominately type I collagen, which is more like scar tissue," Shah said.

In the microfracture procedure, small holes are drilled in the bone beneath the damaged cartilage to create a new blood supply to stimulate the growth of new cartilage.

Tests in lab animals showed that the nanoscopic material produced better results than the microfracture procedure alone, the researchers said.

The study was published online in this week's Proceedings of the National Academy of Sciences.

More information

The American Academy of Orthopaedic Surgeons has more about cartilage damage and repair.



-- Robert Preidt



SOURCE: Northwestern University, news release, Feb. 1, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Bioactive glass nanofibers produced
2. Natural Delivery OK in Cases of Intrauterine Growth Restriction
3. Melatonin precursor stimulates growth factor circuits in brain
4. MetricStream Achieves Record Revenue Growth in 2009 with Global Customer Adoption of its Enterprise GRC Platform and Solutions
5. 3-D scaffold provides clean, biodegradable structure for stem cell growth
6. Growth factor gene shown to be a key to cleft palate
7. Explosive Growth Fuels Expansion of ADVOCATE's Management Team
8. CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth
9. Centage Corporation Reports 16% Growth in 2009; Planning Maestro, Business Performance Management Software Implementations on the Rise
10. Treating Low Growth Hormone in Childhood May Thwart Later Ills
11. MessageSolution Awards Global Partners for Outstanding Global Support and Strategic Market Growth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... ... ... blind and certified personal trainer is helping to develop a weight loss fitness plan that ... the two major problems leading the fitness industry today:, , All ... They don’t eliminate all the reasons people quit their exercise program , ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... ... the United States, named Dr. Sesan Ogunleye, as the Medical Director of its new ... the facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Analysis 2016 - Forecast to 2022" report to their ... contains up to date financial data derived from varied research ... trends with potential impact on the market during the next ... which comprises of sub markets, regional and country level analysis. ...
(Date:6/23/2016)... , June 23, 2016 Research ... Pharma News Issue 52" report to their offering. ... in influenza treatment creates a favourable commercial environment for MedImmune ... growing patient base that will serve to drive considerable growth ... vaccine would serve to cap sales considerably, but development is ...
(Date:6/23/2016)... , June 23, 2016 , ... Thursday, July 7, 2016 , , , , LOCATION: , ... , , , , EXPERT PANELISTS:  , , , Frost ... Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh ... The global pharmaceutical industry is witnessing an exceptional era. Several ...
Breaking Medicine Technology: