Navigation Links
Nanofiber Gel May Spur Growth of New Knee Cartilage
Date:2/4/2010

Animal study reveals new way to repair damage with natural tissue

THURSDAY, Feb. 4 (HealthDay News) -- A new nanofiber gel that promotes cartilage growth in joints has been developed by U.S. researchers.

The material is injected into the damaged joint and stimulates bone marrow stem cells to produce natural cartilage, without the need for expensive growth factors. No current therapy can do this, according to the researchers, from Northwestern University.

Many people -- including amateur and professional athletes and older adults -- have damaged cartilage, which can lead to joint pain and loss of physical function and eventually to osteoarthritis.

"Cartilage does not regenerate in adults. Once you are fully grown, you have all the cartilage you'll ever have," the study's lead author, Ramille N. Shah, an assistant professor of materials science and engineering at the McCormick School of Engineering and Applied Science and assistant professor of orthopedic surgery at the Feinberg School of Medicine, said in a university news release.

The nanoscopic material prompts stem cells in bone marrow to produce cartilage containing type II collagen and repair the damaged joint, the researchers explained. Type II collagen is the major protein in articular cartilage, which is the smooth, white connective tissue that covers the ends of bones where they meet to form joints.

"A procedure called microfracture is the most common technique currently used by doctors, but it tends to produce a cartilage having predominately type I collagen, which is more like scar tissue," Shah said.

In the microfracture procedure, small holes are drilled in the bone beneath the damaged cartilage to create a new blood supply to stimulate the growth of new cartilage.

Tests in lab animals showed that the nanoscopic material produced better results than the microfracture procedure alone, the researchers said.

The study was published online in this week's Proceedings of the National Academy of Sciences.

More information

The American Academy of Orthopaedic Surgeons has more about cartilage damage and repair.



-- Robert Preidt



SOURCE: Northwestern University, news release, Feb. 1, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Bioactive glass nanofibers produced
2. Natural Delivery OK in Cases of Intrauterine Growth Restriction
3. Melatonin precursor stimulates growth factor circuits in brain
4. MetricStream Achieves Record Revenue Growth in 2009 with Global Customer Adoption of its Enterprise GRC Platform and Solutions
5. 3-D scaffold provides clean, biodegradable structure for stem cell growth
6. Growth factor gene shown to be a key to cleft palate
7. Explosive Growth Fuels Expansion of ADVOCATE's Management Team
8. CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth
9. Centage Corporation Reports 16% Growth in 2009; Planning Maestro, Business Performance Management Software Implementations on the Rise
10. Treating Low Growth Hormone in Childhood May Thwart Later Ills
11. MessageSolution Awards Global Partners for Outstanding Global Support and Strategic Market Growth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... ... 20, 2017 , ... The Business Architecture Guild® is pleases ... Guide )v 6.0 is now available for member download. This release is dedicated ... , Non-members may download the Part 1 Introduction for free at ...
(Date:7/20/2017)... NC (PRWEB) , ... July 20, 2017 , ... LINET, ... the latest innovation to their product line: the AVE 2 birthing bed. , Perfectly ... helps bring a new level of comfort and efficiency to every phase of childbirth. ...
(Date:7/20/2017)... ... July 19, 2017 , ... At Creekwood Dental Arts, Drs. Donna G. ... treatment and dental implants in Waco, TX, using the latest dental technology ... by Tekscan®, they can capture details in the oral cavity for accurate diagnoses and ...
(Date:7/20/2017)... ... July 19, 2017 , ... Adolfson & Peterson ... manager, Josh Christensen. As a leader in healthcare construction, AP has successfully built ... resume in the Midwest with Josh now on board. , Josh brings ...
(Date:7/20/2017)... ... ... “Fidget”: a fun-filled, action-packed memoir of adventures. “Fidget” is the creation of ... who was a summa cum laude graduate of Gardner Webb University. She has won ... her retirement from public school, Lynn continued to pursue her love for music through ...
Breaking Medicine News(10 mins):
(Date:7/12/2017)... , July 12, 2017  Eli Lilly and Company (NYSE: ... with generic companies to resolve pending patent litigation in the ... Virginia regarding the Cialis ® (tadalafil) unit ... April 26, 2020. As part of the agreement, Cialis exclusivity ... 27, 2018. "The unit dose patent for Cialis ...
(Date:7/11/2017)... , July 11, 2017  Dr. Echenberg, founder of Echenberg Institute, ... program to patients who suffer from painful intercourse and other painful pelvic ... vaginal atrophy due to menopause. ... VuVatech LLC ... created by Sarasota, Florida -based start-up company, VuVatech LLC, ...
(Date:7/10/2017)... Calif. , July 10, 2017  The tenth ... Boston, MA at the Sheraton ... value and unparalleled access to global decision makers and ... draw 800+ life science leaders during two impactful days. ... and provides delegates with additional networking opportunities with 4,500+ ...
Breaking Medicine Technology: