Navigation Links
Nanofiber Gel May Spur Growth of New Knee Cartilage
Date:2/4/2010

Animal study reveals new way to repair damage with natural tissue

THURSDAY, Feb. 4 (HealthDay News) -- A new nanofiber gel that promotes cartilage growth in joints has been developed by U.S. researchers.

The material is injected into the damaged joint and stimulates bone marrow stem cells to produce natural cartilage, without the need for expensive growth factors. No current therapy can do this, according to the researchers, from Northwestern University.

Many people -- including amateur and professional athletes and older adults -- have damaged cartilage, which can lead to joint pain and loss of physical function and eventually to osteoarthritis.

"Cartilage does not regenerate in adults. Once you are fully grown, you have all the cartilage you'll ever have," the study's lead author, Ramille N. Shah, an assistant professor of materials science and engineering at the McCormick School of Engineering and Applied Science and assistant professor of orthopedic surgery at the Feinberg School of Medicine, said in a university news release.

The nanoscopic material prompts stem cells in bone marrow to produce cartilage containing type II collagen and repair the damaged joint, the researchers explained. Type II collagen is the major protein in articular cartilage, which is the smooth, white connective tissue that covers the ends of bones where they meet to form joints.

"A procedure called microfracture is the most common technique currently used by doctors, but it tends to produce a cartilage having predominately type I collagen, which is more like scar tissue," Shah said.

In the microfracture procedure, small holes are drilled in the bone beneath the damaged cartilage to create a new blood supply to stimulate the growth of new cartilage.

Tests in lab animals showed that the nanoscopic material produced better results than the microfracture procedure alone, the researchers said.

The study was published online in this week's Proceedings of the National Academy of Sciences.

More information

The American Academy of Orthopaedic Surgeons has more about cartilage damage and repair.



-- Robert Preidt



SOURCE: Northwestern University, news release, Feb. 1, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Bioactive glass nanofibers produced
2. Natural Delivery OK in Cases of Intrauterine Growth Restriction
3. Melatonin precursor stimulates growth factor circuits in brain
4. MetricStream Achieves Record Revenue Growth in 2009 with Global Customer Adoption of its Enterprise GRC Platform and Solutions
5. 3-D scaffold provides clean, biodegradable structure for stem cell growth
6. Growth factor gene shown to be a key to cleft palate
7. Explosive Growth Fuels Expansion of ADVOCATE's Management Team
8. CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth
9. Centage Corporation Reports 16% Growth in 2009; Planning Maestro, Business Performance Management Software Implementations on the Rise
10. Treating Low Growth Hormone in Childhood May Thwart Later Ills
11. MessageSolution Awards Global Partners for Outstanding Global Support and Strategic Market Growth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: