Navigation Links
Nanofiber Gel May Spur Growth of New Knee Cartilage

Animal study reveals new way to repair damage with natural tissue

THURSDAY, Feb. 4 (HealthDay News) -- A new nanofiber gel that promotes cartilage growth in joints has been developed by U.S. researchers.

The material is injected into the damaged joint and stimulates bone marrow stem cells to produce natural cartilage, without the need for expensive growth factors. No current therapy can do this, according to the researchers, from Northwestern University.

Many people -- including amateur and professional athletes and older adults -- have damaged cartilage, which can lead to joint pain and loss of physical function and eventually to osteoarthritis.

"Cartilage does not regenerate in adults. Once you are fully grown, you have all the cartilage you'll ever have," the study's lead author, Ramille N. Shah, an assistant professor of materials science and engineering at the McCormick School of Engineering and Applied Science and assistant professor of orthopedic surgery at the Feinberg School of Medicine, said in a university news release.

The nanoscopic material prompts stem cells in bone marrow to produce cartilage containing type II collagen and repair the damaged joint, the researchers explained. Type II collagen is the major protein in articular cartilage, which is the smooth, white connective tissue that covers the ends of bones where they meet to form joints.

"A procedure called microfracture is the most common technique currently used by doctors, but it tends to produce a cartilage having predominately type I collagen, which is more like scar tissue," Shah said.

In the microfracture procedure, small holes are drilled in the bone beneath the damaged cartilage to create a new blood supply to stimulate the growth of new cartilage.

Tests in lab animals showed that the nanoscopic material produced better results than the microfracture procedure alone, the researchers said.

The study was published online in this week's Proceedings of the National Academy of Sciences.

More information

The American Academy of Orthopaedic Surgeons has more about cartilage damage and repair.

-- Robert Preidt

SOURCE: Northwestern University, news release, Feb. 1, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Bioactive glass nanofibers produced
2. Natural Delivery OK in Cases of Intrauterine Growth Restriction
3. Melatonin precursor stimulates growth factor circuits in brain
4. MetricStream Achieves Record Revenue Growth in 2009 with Global Customer Adoption of its Enterprise GRC Platform and Solutions
5. 3-D scaffold provides clean, biodegradable structure for stem cell growth
6. Growth factor gene shown to be a key to cleft palate
7. Explosive Growth Fuels Expansion of ADVOCATE's Management Team
8. CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth
9. Centage Corporation Reports 16% Growth in 2009; Planning Maestro, Business Performance Management Software Implementations on the Rise
10. Treating Low Growth Hormone in Childhood May Thwart Later Ills
11. MessageSolution Awards Global Partners for Outstanding Global Support and Strategic Market Growth
Post Your Comments:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... for mental health professionals, announced today its affiliation with Tennessee Counseling Association. ... solutions to the network of the Tennessee Counseling Association, adding exclusive benefits and ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American Institutes ... Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , ... advance care planning, healthcare costs and patient and family engagement. , AIR researchers ...
(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced ... feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as a ... has released tools for healthy coping following a traumatic event. , Trauma sufferers tend ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Story Highlights: ... the health care industry is causing providers to review ... Deloitte offers a suite of solutions for health care ... cost optimization: labor resource analysis, revenue cycle optimization and ... outcomes and better economics ...
(Date:6/24/2016)... SOUTH SAN FRANCISCO, Calif. , June 24, ... GBT ), a biopharmaceutical company developing novel ... with significant unmet needs, today announced the closing ... 6,400,000 shares of common stock, at the public ... the shares in the offering were offered by ...
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
Breaking Medicine Technology: