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NYUCN receives $4.2 million NIH/NIDA grant to study injecting drug users in Kenya
Date:10/28/2011

a peer case manager to link the person to ART at study-participating HIV clinics, support ART and PwP adherence and care retention.

Both peer case managers and subjects will receive small conditional cash transfers for subject's adherence to HIV care visits. Primary study outcomes will include time to successful linkage to care, time to ART, and community viral load before and after the TLC-IDU initiation. 'Community viral load' will be ascertained by collecting specimens from around nine randomly-selected HIV-positives at each of the 25 sites. This sampling will be done in eight waves over time, to document changes in infectivity (median viral load). This will give good power to detect HIV viral load changes when comparing pre- and post-intervention periods..

Aim 2: Conduct mathematical modeling to estimate community viral load in IDU injecting and sexual networks, and to assess potential population-level impact of the TLC-IDU intervention on numbers of infections averted,and quality-adjusted life expectancy.

Aim 3: Assess the incremental cost-effectiveness ratio of the TLC-IDU model, using a national payer perspective.

This study will provide among the world's first data regarding implementation of the seek, test, treat and retain paradigm with IDUs in sub-Saharan Africa. It will demonstrate the degree to which a combination of structural, biomedical and behavioral interventions can reduce infectivity.

"Partnership with Kenya's national HIV program will allow lessons learned from this study to inform other countries considering how best to address the growing IDU contribution to the HIV epidemic in this high-HIV-burden region," said Kurth.


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Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University
Source:Eurekalert

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