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NYUCD awarded $2.2 million NIH grant to decode genome of caries-causing bacteria
Date:11/3/2011

iologist, demonstrated that these bacteria are transmitted from mother to infant during intimate contact.

"The findings from our new study, as well as the earlier research on Streptoccocus mutans, will help propel the development of a diagnostic test that dentists can administer chairside to identify those at risk," said Dr. Caufield.

"Severe early childhood caries is one of the most prevalent chronic diseases in underprivileged populations," added Dr. Li. "Much still needs to be learned about how the disease develops, and how it can be prevented. Our study will help to fill those gaps."

Co-investigators on the Lb study include Dr. Silvia Argimon, research scientist in cariology and comprehensive care; Dr. Charles Larsen, clinical assistant professor of pediatric dentistry, Dr. Untray T. Brown, clinical associate professor of pediatric dentistry; Dr. Robert Norman, research associate professor of epidemiology & health promotion; and Dr. Peter Catapano, Jr., clinical associate professor of pediatric dentistry, all of the NYU College of Dentistry. Dr. Catapano is also a clinical associate professor of pediatrics at the NYU School of Medicine and director of the pediatric dental clinic at Bellevue Hospital Center.

Additional co-investigators include Dr. Paul O'Toole, senior scientist at University College, Ireland; Dr. Julian Parkhill, senior scientist at the Wellcome Trust Sanger Institute; Dr. Rob Desalle, curator of the Sackler Institute for Comparative Genomics of the American Museum of Natural History; and Dr. Paul J. Planet, a research associate at the American Museum of Natural History and a fellow in the pediatric infectious disease division of the Columbia College of Physicians and Surgeons Children's Hospital of New York.

Drs. Caufield and Li are also focusing on how severe early childhood caries affects children living on American Indian reservations. They are participating in a series of outreaches to Indi
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Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University
Source:Eurekalert

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