Navigation Links
NYU researchers identify new neurological deficit behind lazy eye

Researchers at New York University's Center for Neural Science have identified a new neurological deficit behind amblyopia, or "lazy eye." Their findings, which appear in the most recent issue of the Journal of Neuroscience, shed additional light on how amblyopia results from disrupted links between the brain and normal visual processing.

Amblyopia results from developmental problems in the brain. When the parts of the brain concerned with visual processing do not function properly, problems ensue with such visual functions as the perception of movement, depth, and fine detail. It is most prevalent neurological defect of vision in children and adults, affecting 1-3 percent of the population.

Previous research on amblyopia has largely focused on one aspect of visual processingthat in the primary visual cortex, or V1.

However, while abnormalities in V1 explain some amblyopic visual problems, they fail to account for the full range of losses suffered by those with amblyopiaincluding motion perception. With this in mind, the NYU researchers studied a brain area called MT, which has a well-established role in processing information about moving visual objects.

To do this, the researchers studied the visual processing of macaque monkeys, examining those who had normal vision and those whose vision was impaired by amblyopia. The researchers recorded both the monkeys' ability to detect motion and how MT's neurons functioned in this process.

Their results showed striking changes in neuron activity in MT. In monkeys with normal vision, the MT neurons responded through both eyes. However, in those with amblyopia, the MT neurons showed stronger response in one eyeusually the one not affected by the disorder. Normal visual motion perception relies on neurons that integrate information about the position of moving objects as they cross the visual image. The NYU researchers found that this ability to integrate motion information was defective in neurons driven through the affected eye, which might explain the animal's deficits in motion perception.

"This study shows that amblyopia results from changes in the brain that extend beyond the primary visual cortex," said J. Anthony Movshon, director of the Center for Neural Science and the paper's senior author, adding that many other affected neurological regions remain undiscovered.


Contact: James Devitt
New York University

Related medicine news :

1. SWOG names 5 cancer researchers outstanding Young Investigators
2. Adults demonstrate modified immune response after receiving massage, Cedars-Sinai researchers show
3. Researchers identify gene set that shows which patients benefit from chemo after surgery
4. Researchers will test suicide prevention program in high schools
5. Mount Sinai researchers find new target to improve pain management
6. Non-invasive therapy significantly improves depression, UCLA researchers say
7. For the first time, researchers identify and isolate adult mammary stem cells in mice
8. UNH researchers develop improved tool for cycling fitness
9. Sodium MRI gives new insights into detecting osteoarthritis, NYU researchers find
10. Researchers urge reclassification of traumatic brain injury as chronic disease
11. Researchers closer to development of drug to prevent deadly immune response
Post Your Comments:
(Date:11/25/2015)... , ... November 25, 2015 , ... ... has focused on providing comprehensive solutions involving adult stem cell therapies to patients ... officially deemed the “Regenestem” name as a Registered Trademark (RTM). , Organizations are ...
(Date:11/25/2015)... ... 25, 2015 , ... Bunion Bootie , the newest ... of the early holiday shopping season. Starting Wednesday November 25th, Bunion Booties are ... Friday promotional pricing is in addition to any automatic discounts applied when buying ...
(Date:11/24/2015)... ... November 24, 2015 , ... Eric C. Seidel, ... many benefits of the revolutionary BIOLASE WaterLase iPlus 2.0™ system. This advanced laser ... used by a dentist in Gettysburg, PA . From routine visits to ...
(Date:11/24/2015)... ... , ... New patients who wish to seek treatment for missing teeth can ... her Mississauga, ON practice. Dr. Williams has been providing dental service for over 34 ... Missing teeth can lead to a variety of complications if they are not replaced ...
(Date:11/24/2015)... ... ... Charitable giving is at its peak during the holidays. In fact, ... the year totalling over $358 billion in 2014. With more than 1.5 million ... individuals who want to “give back” during the holidays. , “With so many charities ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015 Research and Markets ( ) ... - Global Forecast to 2020" report to their ... for 37.21% of the total market share in 2014. ... region is projected to growth at the highest CAGR ... primarily to the fast growing water, industrial gas treatment, ...
(Date:11/24/2015)... 25, 2015 WuXi PharmaTech (Cayman) Inc. ("WuXi" ... open-access R&D capability and technology platform company serving the ... China and the ... extraordinary general meeting of shareholders held today, the Company,s ... and approve the previously announced agreement and plan of ...
(Date:11/24/2015)... N.C. , Nov. 24, 2015  In the ... projects in an effort to quickly uncover new insights, ... --> --> However, ... a market research project and ensure that all rules ... and industry standards. Another major barrier to efficiently launching ...
Breaking Medicine Technology: