Navigation Links
NYU School of Medicine announces new clinical trial for ulcerative colitis
Date:8/7/2012

New York (August 7, 2012) A new clinical trial designed to study how worm eggs may relieve symptoms of ulcerative colitis (UC) will begin enrolling patients at NYU School of Medicine's Clinical and Translational Science Institute. This unusual therapy has been used in previous clinical trials on patients with inflammatory bowel diseases, but the mechanism of action is unclear.

"The goal of this study is to understand the mechanisms that may explain why worm eggs can improve the symptoms of UC." says the study's Principal Investigator, P'ng Loke, PhD, assistant professor of microbiology. "Understanding these mechanisms may lead to new treatment strategies and also help identify people that are most likely to respond to treatment with worm eggs."

UC is a chronic disease that is characterized by open sores or ulcers in the lining of the colon. According to the Crohn's and Colitis Foundation of America, the disease is estimated to affect 700,000 Americans. Symptoms include abdominal pain and bloody diarrhea. While the cause is unknown, studies suggest that a defective response against commensal (normal microflora) gut bacteria could be responsible.

Colitis is common in North America and Northern Europe, where helminth (parasitic worm) infections are rare. Conversely, the disease is rare in Asia, Africa, and Latin America, where helminth infections are endemic, leading researchers to hypothesize that the worms offer protection against this inflammatory bowel disease. In animal models of autoimmunity these worms have suppressed inflammation, and clinical trials indicate that helminth therapy can be beneficial in relieving symptoms of inflammatory bowel diseases.

In 2005, Dr. Joel Weinstock and colleagues at the University of Iowa published a series of human studies showing that eggs from the pig whipworm Trichuris suis (TSO) had positive effects in both Crohn's disease as well as ulcerative colitis patients, which are two
'/>"/>

Contact: Lorinda Klein
lorindaann.klein@nyumc.org
212-404-3533
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Sugary Sports Drinks Plentiful at U.S. Schools: Study
2. Preschool children who can pay attention more likely to finish college
3. Expert Tips May Help Kids Avoid Allergens at School
4. Signs of ADHD Evident by Preschool, Expert Says
5. CWRU School of Medicine researchers discover gene that permanently stops cancer cell proliferation
6. Shots Should Be on College Kids Back-to-School List
7. LA BioMed offers unique educational and research opportunity to local high school seniors
8. Preschool TV Habits Linked to 4th-Grade Waist Size, Fitness
9. U.S. High Schools Lax in Preventing Dating Abuse: Study
10. U.S. Schools Throwing the Book at Unhealthy Drinks
11. Kids Born Even a Little Early Have Lower School Scores: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/2/2014)... Dennis Thompson HealthDay Reporter ... newborn,s risk of developing celiac disease isn,t reduced by breast-feeding. ... wheat called gluten to an infant,s diet help prevent celiac ... of new studies in the Oct. 2 New England ... rest hopes that a child could avoid celiac disease if ...
(Date:10/2/2014)... Dennis Thompson HealthDay Reporter ... and the District of Columbia now have a total of ... that has been infecting children since the summer, U.S. ... virus have died in recent weeks, but it,s not clear ... those deaths, officials said. Health officials are also trying ...
(Date:10/1/2014)... small protein beta-amyloid is strongly associated with Alzheimer,s disease; ... this peptide is the causal agent of the onset ... such confirmation is that beta-amyloid is not harmful when ... is when it self-assembles to form the so-called amyloid ... target, beta-amyloid alone, but with multiple ones because each ...
(Date:10/1/2014)... Computer modelling of the human eye, the brain of ... neuroscience and new technology, says a QUT leading robotics ... and Engineering Faculty says the new study uses new ... by high-density buildings or tunnels. , "This is a ... "It,s putting two halves of a thing together because ...
(Date:10/1/2014)... 1, 2014) Despite a policy focus on ... disabilities, this vulnerable population continues to have significant ... The Journal of the American Dental Association , ... Tufts University School of Dental Medicine report on ... at-home oral care provided by caregivers to adults ...
Breaking Medicine News(10 mins):Health News:Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds 2Health News:Infant's Early Diet Doesn't Change Celiac Disease Risk, Study Finds 3Health News:42 States Reporting Respiratory Virus That Targets Kids 2Health News:42 States Reporting Respiratory Virus That Targets Kids 3Health News:Laying siege to beta-amyloid, the key protein in Alzheimer's disease 2Health News:Robot researcher combines nature to nurture 'superhuman' navigation 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 3
... April 1 Edifecs announced ... implementation issues that providers, payers, clearinghouses and other healthcare ... new standards. In these sessions, Edifecs will offer ... Edifecs5010(TM) Migration -- a comprehensive set of products, online ...
... climate change and semi-arid regions turn to desert, people ... to be displaced. A mathematical approach to planned relocation ... Operational Research . , Decision scientist Sajjad Zahir at ... Sarker of the University of New South Wales, Canberra, ...
... Stem Cell Biotherapy ("SCB") announced that it filed ... against the Company,s Co-Founder and former President Casey Nabavi ... Nabavi giving rise to patient claims against Nabavi that ... medicine without a license, supervised the injection of stem ...
... the Nation,s Largest Independent Online Retailer of Beauty ... YORK, March 24 Sandow Media, parent company ... site SpaLook.com, and Salu Beauty, parent company of ... scale and reach for beauty product manufacturers. This ...
... is National STD Awareness Month , HARRISBURG, Pa., April ... of the continuing need for men and women to ... diseases, or STDs, as well as the importance of ... providers. "Although many STDs are treatable, screening and early ...
... Innovations, Inc. (NYSE: IMA ), a global leader ... home through the merger of rapid diagnostics and health management, ... elected to the company,s board of directors. Dr. Adashi, a ... and in the Life Sciences was also appointed to serve ...
Cached Medicine News:Health News:Edifecs Launches First of a Series of Edifecs5010(TM) Migration Educational Webinars Addressing 5010 Migration Challenges, Opportunities and Solutions 2Health News:Edifecs Launches First of a Series of Edifecs5010(TM) Migration Educational Webinars Addressing 5010 Migration Challenges, Opportunities and Solutions 3Health News:Relocation, relocation, relocation 2Health News:Stem Cell Biotherapy Sues Casey Nabavi, Co-Founder and Former President, for Conduct Resulting in Claims by SCB Patients Against Nabavi, Embezzling Money and Converting Other Assets Belonging to SCB and for Wrongfully Establishing Cellulogix Biosciences t 2Health News:NewBeauty Magazine and SpaLook.com Create Strategic Alliance With Salu Beauty and SkinStore.com 2Health News:NewBeauty Magazine and SpaLook.com Create Strategic Alliance With Salu Beauty and SkinStore.com 3Health News:Pennsylvania Department of Health Urges Greater Awareness of, Testing for Sexually Transmitted Diseases 2Health News:Eli Y. Adashi, MD, MS, FACOG, Joins Inverness Medical Innovations' Board of Directors 2
(Date:10/2/2014)... 2, 2014  InfinityQS International, Inc., the global ... announces key client speakers for Infusion Chicago, its ... The event will be held Oct. 9-10, 2014, ... include projects from Coloplast, The Kellogg Company, Biomet, ... King. The two-day event will also include best ...
(Date:10/2/2014)... , Oct. 2, 2014   Softworld, Inc. announced ... new practice solely focused on the specific needs of ... While Softworld has already been highly successful in the ... additional capabilities to support the quality, regulatory, and validation ... now a combination of the current Biometric team and ...
(Date:10/2/2014)... Oct. 2, 2014   West Pharmaceutical Services, Inc. ... in innovative solutions for injectable drug administration, announced today ... include a new site in Waterford, Ireland ... for insulin injector cartridges and other high-value packaging components, ... biotech customers. Once operational, this new site could bring ...
Breaking Medicine Technology:InfinityQS Infusion Chicago to Spotlight Manufacturers' Key Successes in Achieving Enterprise Quality 2InfinityQS Infusion Chicago to Spotlight Manufacturers' Key Successes in Achieving Enterprise Quality 3Softworld, Inc. Launches Strategic Division Dedicated to Life Sciences Consulting 2West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 2West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 3West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 4West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 5
... Jan. 12, 2011 Webmedx , the third largest ... provider in the U.S., today announced it has received the ... the 2010 Top 20 Best in KLAS Awards: Software ... Best in KLAS 2010 award, the company was also rated ...
... 2011 RESMED INC. (NYSE: RMD ), announced ... its results for the second quarter and six months of ... with ResMed,s results will be issued after 1:00 p.m. pacific ... webcast to review its results, market trends, and future outlook. ...
Cached Medicine Technology:Webmedx Named Best in KLAS and Ranked #1 Transcription Services Vendor for Second Year in a Row 2Webmedx Named Best in KLAS and Ranked #1 Transcription Services Vendor for Second Year in a Row 3ResMed Announces Conference Call and Webcast to Discuss Second Quarter 2011 Results 2
... circulating testosterone exists as unbound or free ... to SHBG with high affinity [1], while ... Both the albumin-bound and free fractions may ... testosterone action. Measurement of the free or ...
... active hormone synthesized within the follicular cells ... synthesized via a series of steps involving: ... (ii) iodination of tyrosine residues in the ... and 3,5-diiodotyrosine (MIT and DIT), and (iii) ...
... factor binding protein-3 (IGFBP-3) is the main binding ... as a component of the ~150 kDa ternary ... of IGF-I or IGF-II and ALS, allowing IGFBP-3, ... the IGFs. The molar concentration of IGFBP-3 in ...
... (GH) is a monomeric protein produced and ... gland. GH is released from the pituitary ... under the regulatory control of hypothalamic somatostatin ... timing and frequency of GH release appears ...
Medicine Products: