Navigation Links
NYU Langone expert calls for awareness, research of sudden death in patients with epilepsy
Date:11/10/2011

Over time, epileptic seizures can lead to major health issues, including significant cognitive decline and even death, warns Orrin Devinsky, MD, professor, Departments of Neurology, Neurosurgery and Psychiatry at NYU Langone Medical Center. In a review article in the Nov. 10, 2011 issue of the New England Journal of Medicine, Devinsky addresses the magnitude of sudden, unexpected death in epilepsy (SUDEP) and offers guidance to patients, physicians and families of those with epilepsy about the risk factors, possible causes and interventional measures.

"Although most people with epilepsy live full and productive lives, doctors may too readily assure patients that seizures will never hurt the brain and are never fatal," writes Devinsky. "If patients are aware that seizures can be deadly, they may be more motivated to adhere to antiepileptic drug regimens and avoid lifestyle choices that increase the likelihood of them."

According to the article, SUDEP usually occurs in chronic, severe cases of epilepsy. But it is estimated that 2.7 million Americans suffer from some form of epilepsy and, even under specialized care, 25 percent of these patients fail to achieve adequate control of their seizures, making therapies less effective and requiring more intensive and comprehensive care than is available through a regular neurologist.

According to Devinsky, the rate of SUDEP increases with the duration and severity of epilepsy. While the exact mechanisms are not known, Devinsky identifies several risk factors associated with known cases of SUDEP, which includes a high prevalence of seizure just prior to an event, an impaired respiratory condition, slowing or shutting down of cerebral functions and cardiac events.

Devinsky points to a long-term cohort study conducted in Finland of 245 patients diagnosed with epilepsy as children which found that SUDEP may have been responsible for 38 percent of the 60 deaths that occurred over the 40 year span. The overall incidence of SUDEP is likely underestimated, adds Devinsky, because of incomplete databases and the fact that the cause may not be appropriately identified by coroners, medical examiners and physicians who are unaware of the diagnostic criteria for SUDEP. A reduction in sudden deaths among patients with epilepsy may be achieved through:

  • Increased awareness by the general public and medical community
  • Improved prevention and treatments of epilepsy
  • Further development and use of devices that detect seizures and can alert caretakers
  • Improved understanding of the mechanisms of SUDEP
  • Conducting interventional trials to prevent the progression of life-threatening seizure to sudden death

'/>"/>
Contact: Craig Andrews
craig.andrews@nyumc.org
212-404-3511
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Related medicine news :

1. NYU Langone rheumatologists share insight with online RA community
2. NYU Langone Medical Center awarded $4.5 million for breast cancer research
3. NYU Langone Medical Center cardiologists present at ACC 60th Annual Scientific Session
4. NYU Langone offers new imaging technique to advance robotic surgery for patients
5. NYU Langone Department of Orthopaedic Surgery chosen to participate in joint replacement registry
6. NYU Langone Medical Center receives NIH Directors Transformative Research Projects award
7. NYU Langone scientists find key pathway implicated in progression of childhood cancer
8. NYU Langone offers vascular-targeted photodynamic therapy for localized prostate cancer
9. Experts Debate Tylenols Safety for Asthmatic Kids
10. NSF-funded research fellowship program to focus on producing experts to aid people with disabilities
11. Experts challenge government on special needs reforms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Yisrayl Hawkins, ... week that explains one of the most popular and least understood books in the ... cryptic and puzzling descriptions that have baffled scholars for centuries. Many have tossed it ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance ... management, will showcase a range of technology and learning solutions at the 68th ... and Expo to be held October 14–18, 2017 at the Mandalay Bay Resort ...
(Date:10/12/2017)... ... , ... The American College of Medical Informatics (ACMI) will present the 2017 ... Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is ... pioneer in the field of medical informatics, this prestigious award is presented to an ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s ... the 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. ... Center for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, ...
(Date:10/12/2017)... FL (PRWEB) , ... October 12, 2017 , ... ... presenting the latest in wound care advancements to physician colleagues, skilled nursing facility ... is titled, "Navigating the Treacherous Waters of Wound Care." , "At many of ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017  Eli Lilly and Company (NYSE: ... for the third quarter of 2017 on Tuesday, October ... on that day with the investment community and media ... The conference call will begin at 9 a.m. Eastern ... a live webcast of the conference call through a ...
(Date:9/28/2017)... -- Hill-Rom Holdings, Inc. (NYSE: HRC), will host its ... on Friday, November 3, 2017, beginning at 7:00 a.m. ... 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... and guidance for 2018, Hill-Rom executives will also highlight ... and long-range financial outlook through 2020. ...
(Date:9/25/2017)... AMSTERDAM , Sept. 25, 2017   ... Trial Master File solutions, today—from the IQPC Trial ... Amsterdam , NL)—announced that EastHORN Clinical Services ... its clinical programs and TMF management. EastHORN, a ... Montrium,s eTMF platform to increase transparency to enable ...
Breaking Medicine Technology: