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NYU Langone Medical Center receives NIH Director's Transformative Research Projects award
Date:9/30/2010

ental Medicine, and Microbiology and support multiple studies:

  • Scientists plan to assess the roles of gastric and colonic microbiota related to hormones and metabolism in both humans and mice. One focus is on the major gastric bacterium, H. pylori, that interacts with gastric mucosal neuroendocrine cells that produce leptin and ghrelin, hormones that are central to energy homeostasis.

  • A study will explore the maternal contribution and early development of the colonic microbiota, especially as perturbed by antibiotics, and examine host phenotypes relevant to altered metabolism.

  • A study will examine the relationship in children and young adults of H. pylori to their energy homeostasis hormones.

  • Another study will involve a cohort in the Netherlands which has already enrolled 10,000 pregnant women and has been following their children for 5-6 years.

  • The scientists will examine giving low doses of antibiotics to mice to see whether they gain weight and increase their fat mass, something that has already been documented.


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Contact: Dorie Klissas
dorie.klissas@nyumc.org
212-404-3555
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

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