Navigation Links
NYU Dentistry and Medicine are awarded a $840,864 collaborative grant by the Lustgarten Foundation
Date:3/26/2013

New York University College of Dentistry (NYUCD) and New York University School of Medicine (SOM) researchers have been awarded a four-year $840,864 collaborative grant by the Lustgarten Foundation to investigate a potential link between pancreatic cancer development and endogenous gut microbiota.

The co-investigators, Deepak Saxena, MS, PhD, Assistant Professor, Basic Science and Craniofacial Biology at NYUCD, and George Miller, MD, Assistant Professor; Departments of Surgery and Cell Biology at the SOM, seek to explore the links between the intestinal microbiome, Toll-like receptors (TLRs), and pancreatic cancer.

"Endogenous gut microbiota have recently been appreciated as important regulators of homeostasis in the healthy individual and contributors toward disease during microbiotic imbalance," said Saxena. "The microbiome is also emerging as a contributor to carcinogenesis in extra-pancreatic malignancies such as colon and liver cancer. However, there has been no direct link between pancreatic cancer development and endogenous gut microbiota," he noted.

There are tangential data, however, that support such an association. For example, the oral microbiome in patients with pancreatic cancer has been found to substantially differ from control subjects. Preliminary data suggest that the intestinal microbiome may be an important regulator of pancreatic cancer development in at-risk individuals.

The study proposes to:

  • Define the evolving intestinal microbiome in mice during pancreatic cancer development and progression as well as determine whether humans with pancreatic cancer harbor a distinct microbiome compared with age-matched control patients

  • Directly test whether endoluminal bacteria can affect pancreatic oncogenesis and determine whether selectively modulating the microbiome alters the rate of tumor progression

  • Test the hypothesis that luminal pathogens affect
    '/>"/>

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Melbourne, Florida Dentist Retires and Passes on Her Legacy of High Quality Dentistry
2. Dr. Teddi Olszewski Joins Northampton Family and Cosmetic Dentistry in Northampton, MA
3. Midtown Dentistry releases new Dental Education Video - "WHY DENTAL IMPLANTS?"
4. Dentist Ashburn 'Best of the Best' Awarded to Belmont Dentistry for Excellence by Follow Media Consulting, Inc. in March 2013.
5. Nashville Periodontal Group Is Expanding Their Sedation Dentistry To Include Patients In Forest Hills, TN Needing Dental Anxiety Relief
6. South Charlotte Dentistry Initiates New Emphasis on Comprehensive Dental Treatment
7. Dr. Robert Barr of Barr Family Dentistry in San Jose, CA Receives Top Reviews for Painless Laser Dental Procedures
8. Dr. Daniel Strader of Dallas Designer Smiles Receives Top Reviews as Local Dallas, TX Dentist for Biological Dentistry
9. Solomon Family Dentistry Announces that They are Now Open Seven Days a Week
10. Complimentary Dental Care in Mesa, AZ - One Day Only, February 15th - VibrantDentistry
11. Inaugural issue of the NYU College of Dentistrys JADE online now
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/6/2015)... Beach, Virginia (PRWEB) , ... July 06, 2015 ... ... States choose fat-reduction procedures each year for aesthetic reasons, which is why liposuction ... country. For a particular demographic, however, fat reduction has become more than a ...
(Date:7/6/2015)... Pleasant Grove, Utah (PRWEB) , ... July 06, 2015 , ... ... of Kirk Jowers to its executive management team. Most recently, Jowers held the position ... held for ten years. , After spending a decade building the institute, Jowers states ...
(Date:7/6/2015)... ... July 06, 2015 , ... Health care systems and genomics projects have ... field to access and use this “Big Data” to improve health and cut costs ... Officer of the Mount Sinai Health System in New York City. Physicians will have ...
(Date:7/6/2015)... ... July 06, 2015 , ... With a new community program in ... Save Our Youth and announced a new charity campaign to raise funds in support ... and drug abuse. Livonia Save Our Youth is a coalition created especially to educate ...
(Date:7/6/2015)... ... July 06, 2015 , ... Promero, ... Technologies selected Aspect Software Unified IP contact center solution hosted by Promero. ... Unified IP as its future call center platform. , Promero will implement ...
Breaking Medicine News(10 mins):Health News:Learn How CoolSculpting® and Liposuction in Virginia Beach Help Military Members Stay the Course 2Health News:Learn How CoolSculpting® and Liposuction in Virginia Beach Help Military Members Stay the Course 3Health News:doTERRA Welcomes Kirk Jowers to Its Executive Team 2Health News:doTERRA Welcomes Kirk Jowers to Its Executive Team 3Health News:doTERRA Welcomes Kirk Jowers to Its Executive Team 4Health News:Mount Sinai CEO Kenneth L. Davis, MD: Our Ability to Access Information in Real Time to Prevent Disease is Drawing Closer 2Health News:Mount Sinai CEO Kenneth L. Davis, MD: Our Ability to Access Information in Real Time to Prevent Disease is Drawing Closer 3Health News:Mount Sinai CEO Kenneth L. Davis, MD: Our Ability to Access Information in Real Time to Prevent Disease is Drawing Closer 4Health News:Mount Sinai CEO Kenneth L. Davis, MD: Our Ability to Access Information in Real Time to Prevent Disease is Drawing Closer 5Health News:Bowker Insurance Group and Nonprofit Livonia Save Our Youth Initiate New Charity Campaign in Livonia, MI to Provide for The Health and Safety of The Communities’ Youth 2Health News:Bowker Insurance Group and Nonprofit Livonia Save Our Youth Initiate New Charity Campaign in Livonia, MI to Provide for The Health and Safety of The Communities’ Youth 3Health News:Aspect Software Unified IP, Hosted by Promero, Selected by Randstad Technologies 2Health News:Aspect Software Unified IP, Hosted by Promero, Selected by Randstad Technologies 3
... 2011 (Toronto) A workplace,s key employees may be at ... according to a new study by the Centre for Addiction ... workers, 18 per cent reported that their job was "highly ... greater if workers were managers or professionals, if they thought ...
... News) -- For many people, their communication skills with ... In fact, spouses sometimes communicate with each other ... "People commonly believe that they communicate better ... lead people to overestimate how well they communicate, a ...
... American Association of Clinical Endocrinologists (AACE) has released new ... osteoporosis. Loyola physician Pauline Camacho, MD, was part of ... major public health issue. These recommendations were developed ... the quality of life for patients. They explain new ...
... , MONDAY, Jan. 24 (HealthDay News) -- Many middle-aged women ... their blood pressure, researchers say. High systolic blood pressure ... factor for cardiovascular disease and its common outcomes -- heart ... women around the world, according to the report released Jan. ...
... , MONDAY, Jan. 24 (HealthDay News) -- Continual ... of the brain that control fear, vigilance and emotion, a ... of brain scans taken among troops recently deployed to Afghanistan, ... journal Molecular Psychiatry . "For the first time ...
... , MONDAY, Jan. 24 (HealthDay News) -- Preparing small doses ... dangerous dosing errors for infants and small children, warns a ... potent drugs for young patients are often prepared from stock ... equipment does not permit the accurate measurement of volumes that ...
Cached Medicine News:Health News:Workers most invested in their jobs have highest stress levels, CAMH study shows 2Health News:Close Relationships Sometimes Mask Poor Communication 2Health News:Loyola physician helps develop national guidelines for osteoporosis 2Health News:Lowering BP Can Help Cut Women's Heart Disease Risk 2Health News:Stress of War Spurs Changes in Brain Activity, Study Finds 2Health News:Preparing Small Doses of Medication From Syringes Called Risky 2
(Date:7/6/2015)... N.J. , July 6, 2015 ... on developing novel therapeutics that target inflammation and ... Bradford , M.D., PhD, as Chief Medical Officer. ... company,s clinical development strategy and programs, which include ... other inflammatory and fibrotic conditions.  Bill is an ...
(Date:7/6/2015)... July 6, 2015   Cepheid (Nasdaq: CPHD ... for its 2015 second quarter ended June 30, 2015 ... the market. The Company will host a ... July 23, 2015, to discuss the results.  To access ... http://ir.cepheid.com at least 15 minutes before the scheduled ...
(Date:7/6/2015)... 2015 China Information Technology, Inc. (the "Company" ... integrated cloud-based platform, exchange, and big data solutions in ... Company launched its mobile app for Healthcare One Pass, ... on mobile devices. The Company jointly hosted the launch ... Bureau and Shenzhen News Net.   The mobile ...
Breaking Medicine Technology:Moerae Matrix, Inc. (Moerae) Appoints Bill Bradford, M.D., PhD, as Chief Medical Officer 2CNIT Launches the Mobile App for Healthcare One Pass 2CNIT Launches the Mobile App for Healthcare One Pass 3CNIT Launches the Mobile App for Healthcare One Pass 4
... with a low-profile, roomy pouch to ... site during arthroscopic surgery. Available with ... drainage. , ,The arthroscopy sheets ... pack, or in custom trays. For ...
The Abbott Commander is an automated, high-throughput immunoassay testing system. The Commander System consists of the Flexible Pipetting Center, the Parallel Processing Center, and the Dynamic Incub...
... Sequence Detection System is a complete, ... quantitates nulceic acid sequences. In real-time ... product is made possible by combining ... software in a single instrument. Quantitative ...
... CELL-DYN 3200 sets a benchmark of ... scatter for WBC, RBC, PLT and ... the needs of today's laboratory. The ... differential analysis, automated sample handling, comprehensive ...
Medicine Products: