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NYSCF - Robertson investigator publishes research to better understand pluripotent stem cells
Date:3/8/2011

NEW YORK CITY (March 7, 2011) Paul Tesar, PhD, of Case Western Reserve University, a member of the inaugural class of The New York Stem Cell Foundation Robertson Investigators, published his research on the ability to isolate epiblast stem cells from preimplantation mouse embryos. This research enhances our understanding of the many forms of pluriportent stem cells that scientists use for researching so many debilitating diseases.

"I think that this paper will change the way people think about what human ES cells represent from a developmental perspective," said Dr. Kevin Eggan, NYSCF Chief Scientific Officer and Associate Professor of Stem Cell and Regenerative Biology at the Harvard Stem Cell Institute.

The study, "Isolation of Epiblast Stem Cells from Preimplantation Mouse Embryos", was published in Cell Stem Cell on March 4th, 2011. In 2007, Dr. Tesar was the lead author on the study that first isolated mouse epiblast stem cells from post-implantation mouse embryos when he was a graduate student in the NIH-Oxford Biomedical Research Scholars program, splitting his time between the two institutions.

Dr. Tesar's research focuses on understanding how different cell types in the nervous system are initially formed during development and how they are maintained throughout adult life. "My hope is that by understanding these basic questions we will be able to prevent or repair damage caused by disease, aging, and injury," said Dr. Tesar. "Research in my lab has the potential to impact a number of devastating neurodegenerative and mental health conditions such as Parkinson's disease, ALS, Hungtington's disease, autism, and multiple sclerosis."

Research in the Tesar lab aims to develop new strategies to restore function in patients afflicted with myelin-based disorders. Loss of myelin results in an impairment in the body's ability to send signals along the neurons. "Dr. Tesar is a wonderful young scientist and the research he is
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Contact: Nadine Woloshin
nwoloshin@rubenstein.com
212-843-8041
New York Stem Cell Foundation
Source:Eurekalert

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