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NUCRYST Announces Management Realignment and R&D Portfolio Change
Date:4/30/2008

Turner for her contributions during her tenure at NUCRYST, and we wish her success in her future endeavors."

About Clostridium difficile

Clostridium difficile (also called C. difficile or C. diff) is a bacterium that is recognized as the major causative agent of colitis (inflammation of the colon) and diarrhea that may occur following antibiotic intake. C. difficile infection represents one of the most widespread hospital infections around the world. C. difficile may complicate the course of ulcerative colitis or Crohn's disease and it is responsible for a significant occurrence of diarrhea in AIDS patients. According to the Centers for Disease Control and Prevention, each year in the United States C. difficile is responsible for tens of thousands of cases of diarrhea and at least 5,000 deaths.

About NUCRYST Pharmaceuticals

NUCRYST Pharmaceuticals (NASDAQ: NCST; TSX: NCS) develops, manufactures and commercializes medical products that fight infection and inflammation using its patented atomically disordered nanocrystalline silver technology. Smith & Nephew plc sell a range of advanced wound care products under their Acticoat(TM) trade mark. Acticoat(TM) products incorporate NUCRYST's SILCRYST(TM) coatings and are sold in over 30 countries. NUCRYST is also developing pharmaceutical products to address medical conditions that are characterized by both infection and inflammation. The Company has developed its proprietary nanocrystalline silver in a powder form, referred to as NPI 32101 for use in medical devices and as an active pharmaceutical ingredient.

Acticoat(TM) is a trademark of Smith & Nephew plc

SILCRYST(TM) is a trademark of NUCRYST Pharmaceuticals Corp.

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SOURCE NUCRYST Pharmaceuticals Corp.
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