Navigation Links
NSF grant will aid Wayne State professors' mathematical modeling of fatty liver predictors
Date:1/19/2012

sponse to disturbances, we can actually achieve a better model with narrower levels of error associated with our predictions," Matthew said.

A preliminary model using cultured liver cells already has achieved some reasonably good results, he said. The current NSF award is geared toward refining that model and collecting more accurate dynamic data.

The team will use perfusion systems that allow researchers to maintain precise levels of metabolites outside cells and to change them instantaneously, looking at response rates of cells to disturbances. Fluorescent lipids will be used so researchers can detect which ones the cells are taking up and how fast they are being redistributed. The team then can model the nature of metabolites being distributed.

"We're looking for changes that occur in minutes to hours in order to refine the model," Matthew said. "The liver typically begins responding within minutes."

Researchers must ascertain the accuracy of prediction at the cellular level before moving to animals and beyond, he said.

"We want our model to predict with a limited amount of data in order to identify which areas might be the key differences between individuals," Matthew said. "That allows biologists and physicians to narrow their focus to particular areas and possibly screen particular enzymes as drug targets.

"Our long-term goal is to use these kinds of models to find out why different people respond to treatments in different ways, so that we can develop a personalized medicine approach to treating the liver or any other tissues."


'/>"/>
Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Childhood cancer research grant awarded to the Research Institute at Nationwide Childrens Hospital
2. Wayne State receives DOD grant; study may give insight to slow or halt breast cancer
3. Autism Speaks awards 47 new research grants funding
4. Boston University researcher awarded 2 NIH grants
5. Emory and US CDC partner to continue building global public health network with $6 million grant
6. UW Medical Center granted magnet status for excellence in nursing care
7. RI Hospital receives $1.5 million grant to study treatments for body dysmorphic disorder
8. University of Kentucky researchers awarded CDC grant to study cancer survival in Appalachia
9. Kessler Foundation receives grant to study cognitive reserve in traumatic brain injury
10. Kessler Foundation receives grants to study health disparities in people with disabilities
11. $3.8 million grant investigates link between sleep apnea and atrial fibrillation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... December 26, 2014 DW-InductionHeating.com (DaWei Induction ... designing, researching and developing, producing and marketing of a ... the business announces their new series of induction ... of the company, induction brazing refers to ... special filler material and heat. The manager says that ...
(Date:12/25/2014)... TX (PRWEB) December 26, 2014 This ... state of the global Sterilizers industry with a focus ... on the market status of the Sterilizers manufacturers and ... companies and individuals interested in the industry. This report ... definition, applications and manufacturing technology. In this part, the ...
(Date:12/25/2014)... The report “TS-1 (Colorectal Cancer) – Forecast ... treatment landscape, unmet needs, current pipeline and commercial opportunities ... drug which is typically used for treating colorectal cancer. ... treating gastric cancer and pancreatic cancer. TS-1 is composed ... first approved in 1999 in Japan for the treatment ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of ... its new selection of black one-shoulder cocktail dresses . ... they are available at discounted prices, up to 70% off. ... last for three weeks only. You know, we have thousands ... interested in our new items can visit our website for ...
(Date:12/25/2014)... Recently, BellasDress has launched its ... dresses. BellasDress has chosen their best-selling lace wedding dresses, ... the holiday season. , Now, BellasDress.com features popular ... here at discount prices. The business hopes everyone can ... , “All our elegant products are made ...
Breaking Medicine News(10 mins):Health News:Induction Brazing Equipment Series From DaWei Induction Heating Co., A Reliable Supplier Of Induction Heating Equipment 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:BellasDress.com’s Christmas Sale: Trendy Wedding Dresses With Big Discounts 2
... performance and lifestyle brand is paired with LensCrafters, ... 500 North American stores, MASON, Ohio, June ... at more than 500 select LensCrafters locations, North ... customers the,combined benefits of Oakley,s popular and innovative ...
... The Pennsylvania Breast Cancer Coalition announces special press,availability ... 12 The following is,being issued by the ... PA Breast Cancer Coalition (PBCC) and the Pennsylvania ... a Homerun Derby event,sliding through each of the ...
... treating high cholesterol, researchers say , , THURSDAY, June 12 ... found a protein in the liver involved in regulating ... provide a new target for treating high cholesterol or ... factor that regulates lipid synthesis in the liver," said ...
... up with Crohn,s & Colitis Foundation of America for this year,s ... Take ... of America (CCFA) is happy to announce that Salix,Pharmaceuticals, a leader in gastroenterology, ... 4 p.m. starting with family,festivities in Overland Park, Kansas a suburb of Kansas ...
... Light Technology and Ancient Relaxation ... Sleep Assistant, PORTLAND, Ore., June 12 For ... sleep but find traditional remedies such as drugs,sound machines ... Resources, Inc. is announcing the first sleep-assisting device,that silently ...
... International (VMI),recently donated a wheelchair-accessible Honda Odyssey ... Foundation. American Honda Motor Co., Inc., (AHM),supplied ... Northstar conversion, which,provides a powered in-floor ramp ... all types of wheelchairs., (Photo: ...
Cached Medicine News:Health News:Oakley Prescription Eyewear Now at Lenscrafters 2Health News:Oakley Prescription Eyewear Now at Lenscrafters 3Health News:Oakley Prescription Eyewear Now at Lenscrafters 4Health News:Scientists Discover Protein Involved in Fat Production 2Health News:National Pharmaceutical Company to Sponsor Popular Kansas City Walk 2Health News:National Pharmaceutical Company to Sponsor Popular Kansas City Walk 3Health News:New Drug-Free Solution for Insomnia 2Health News:Sam Schmidt Receives a Honda Odyssey Converted for Wheelchair Accessibility 2Health News:Sam Schmidt Receives a Honda Odyssey Converted for Wheelchair Accessibility 3
(Date:12/24/2014)... 2014  Commonwealth Cornerstone Group (CCG) today announced the completion ... Tuesday to help fund the expansion and consolidation of healthcare ... Sharon . PHN is the largest ... . It is the largest employer in Sharon,s ... on staff. Currently, PHN Sharon offers scattered services ...
(Date:12/24/2014)... 2014  The International Trade Commission (ITC) issued its final ... Medical. In a notice issued on December 23, the ITC ... on its humidifier was invalid. BMC President, ... are very excited with the ITC,s decision in this case. ... taken since the very beginning on the key patents in ...
(Date:12/24/2014)... LONDON , December 24, 2014 /PRNewswire/ ... expected to grow at an average rate of 8.1%. ... and volume. Hip, knee and spine surgeries are the ... emerging economies they have a lower penetration. Increased number ... use of composites. Non-metallic orthopedic devices have gained popularity ...
Breaking Medicine Technology:Commonwealth Cornerstone Group Announces $8 Million in Tax Credits to Expand and Consolidate Healthcare Services in Sharon 2Commonwealth Cornerstone Group Announces $8 Million in Tax Credits to Expand and Consolidate Healthcare Services in Sharon 3ITC Final Decision Goes Against ResMed (RMD) Monumental Win for 3B/BMC 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3
NS2000 Bipolar Generator provides precise coagulation without tissue sticking....
The Sabre 2400 provides high power performance and key user features to meet today's demanding electrosurgical needs. It is an ideal general-purpose electrosurgical generator....
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
Standard bipolar coagulator...
Medicine Products: