Navigation Links
NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Date:3/26/2008

r genes is frequently found in many types of human cancer and is a crucial step for tumorigenesis. Recently, a number of de-methylating agents have been reported to exhibit potent anti-cancer effects in vitro and in vivo. Therefore, these agents are considered to be useful for cancer therapy. As a matter of fact, two de-methylating drugs 5-Azacitidine and 5-Aza-2-deoxycytidine (decitabine) have been approved for the treatment of myelodysplastic syndromes, a heterogenous group of hematopoietic stem cell disorders that are multifactorial in their etiology. Hung says our results indicate that NSAIDs may function as de-methylating agents via inhibition of DNMTs and may provide a new strategy for the treatment or prevention of cancer. Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine, agrees and said These unique findings by Dr. Hung and colleagues suggest an entirely new function for non-steroidal anti-inflamatory drugs in cancer therapy. This is an exciting advance for the field of Cancer biology.


'/>"/>

Contact: Dr. Wen-Chung Hung
hung1228@ms10.hinet.net
886-752-52000 x5817
Society for Experimental Biology and Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Cerimon to Conduct a Proof of Concept Study for Basiliximab for Noninfectious Uveitis, a Potentially Sight-Threatening Inflammation of the Eye
2. Sirion Therapeutics Receives NDA Acceptance and Priority Review From the FDA for Durezol(TM) in the Treatment of Postoperative Ocular Inflammation
3. A Once-Daily Oral Drug for Chronic Obstructive Pulmonary Disease That Treats COPD-Related Inflammation Could Achieve Blockbuster Status
4. Overweight Hispanic children shown to have vascular inflammation
5. Anti-Inflammatory Drug Improves Glycemia, Lowers Inflammation in Obese, Young Adults
6. TNF-alpha antagonist stops inflammation-induced colon cancer in its tracks
7. Cell-death receptor links cancer susceptibility and inflammation
8. iNOS expression may links chronic biliary inflammation to malignant transformation
9. Diabetes Linked to Blood Vessel Inflammation
10. Low-carb diet reduces inflammation and blood saturated fat in metabolic syndrome
11. Researchers develop powerful tool to study the genetics of inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... , ... July 30, 2015 , ... ... the ‘Mary Jo Lawyer-Spano Mesothelioma Patient Registry Act of 2015’. The bill ... Chris Collins (R-NY), Peter King (R-NY), Betty McCollum (D-MN), Joe Kennedy (D-MA), and ...
(Date:7/30/2015)... ... , ... Using the latest online digital technologies, happiness expert Kay Walker is ... and manage major depression. , “Suicide is 100% preventable. The problem is the medical ... and die needlessly everyday,” says Walker. “I’m out to end suicide. Some may say ...
(Date:7/30/2015)... ... July 30, 2015 , ... Boston Web ... annual All-Stars Summit. Google Partners is the platform for search marketing agencies to ... support and tools necessary to run successful search marketing campaigns. Google Partners also ...
(Date:7/30/2015)... ... July 30, 2015 , ... Between 2012 and 2014 HIV infection rates ... Florida on June 17th. Those untreated heroin use disorders share their needles and ... of dirty needles throughout the community. Ultimately Florida’s HIV infection rates have bolstered to ...
(Date:7/30/2015)... ... 30, 2015 , ... Ocean Hills Recovery has officially been accredited by CARF ... No recommendations means CARF found no areas in the OHR program that needed improvement, ... of all facilities receive. In addition, Ocean Hills was granted the maximum certification period ...
Breaking Medicine News(10 mins):Health News:Bill to Create Patient Registry for Deadly Cancer Introduced in Congress 2Health News:Happiness Expert Develops Pioneering Online Tools for Sufferers of Major Depression, and Who may be Suicidal 2Health News:Happiness Expert Develops Pioneering Online Tools for Sufferers of Major Depression, and Who may be Suicidal 3Health News:Boston Web Marketing Attends Google Partners All-Stars Summit 2Health News:HIV Rates Rise in S. Florida, Harbor Village Comments on Health News Florida's Recent Article 2Health News:HIV Rates Rise in S. Florida, Harbor Village Comments on Health News Florida's Recent Article 3Health News:Ocean Hills Recovery Receives Accreditation from CARF International 2
... of Breast Cancer Awareness Month, a campaign that has boosted better ... it is possible that even they may be a victim // ... to be worse than for women, mainly because of the lack ... off” the symptoms: a lump, pain or sensitivity, or a clear ...
... has been denied Herceptin earlier has won her case so ... treatment. , ,Herceptin is a drug mostly used for ... are prescribed the drug, as Barbara Clark only had a ... this year, the doctors denied giving her Herceptin. Because, Herceptin ...
... version of a human protein has been found to alleviate ... could be the basis for developing a new drug for ... been found to function by blocking the transmission of chemical ... idea that the protein, called pre-ligand assembly domain protein or ...
... the most common causes of sexually transmitted infection (STI) in ... most of which are harmless. HPV is a virus, which ... in the anal, genital, oral cavities or respiratory locations of ... easily recognized sign of genital HPV infection. The presence an ...
... has been reported at a seniors' home in Toronto and experts ... of four residents at the home. ,Infectious diseases expert Dr. Neil ... outbreak and stressed that the virus could not only be the ... is always a potential for a new virus to cause a ...
... study which helps to understand the benefits of reflexology, ... patients to ease the pain they face due to ... be carried out by Researchers from Michigan State University. ... therapy methods reflexology, guided imagery and reminiscence therapy. “Reflexology ...
Cached Medicine News:Health News:Men Victims Of Breast Cancer? 2Health News:Synthetic protein found to relieve arthritis symptoms in animal model 2
(Date:7/30/2015)... , July 30, 2015 ... focused on gynecologic disease, announced today it ... results after the market close on Thursday, ... conference call and webcast at 4:30pm Eastern.Conference ... 2015 at 4:30pm Eastern/1:30pm Pacific  Domestic: ...
(Date:7/30/2015)... 30, 2015   Sentrian , the Remote ... hospitalization, recently received confirmation from the Food & ... (RPI) solution meets the definition of a "medical ... "Enforcement Discretion." The designation identifies ... FDA regulatory requirements at this time" and clears ...
(Date:7/30/2015)... LONDON , July 30, 2015 ... devices market ? Which areas are going to grow ... report shows you potential revenues to 2025, assessing data, ... report provides 176 tables, charts, and graphs. ... the future market prospects. Our new study lets you ...
Breaking Medicine Technology:FDA Clears Way for Commercial Marketing of Sentrian Remote Patient Intelligence Solution 2FDA Clears Way for Commercial Marketing of Sentrian Remote Patient Intelligence Solution 3Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 2Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 3Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 4Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 5Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 6
... , , NEW YORK, ... customizable webcasting and streaming media solutions and services, will ... Midwest Chapter Event: September Education Program to a virtual ... presentation by Disney Destinations for the leading organization of ...
... , , , Timing is ... , ROSEMONT, Ill., Sept. 1 Trauma patients who sustain ... they arrive at the emergency department. A review article published in ... Academy of Orthopaedic Surgeons (JAAOS) explains that trauma patients who ...
Cached Medicine Technology:Stream57 to Webcast PCMA Midwest Chapter Meeting Live on Sept. 30th 2Trauma 411: Prolonged Surgery Should be Avoided in Certain Cases 2Trauma 411: Prolonged Surgery Should be Avoided in Certain Cases 3
BioVintages Biotin-Trapper™ Streptavidin Magnetic Beads (1 mm - 2 mm) are designed for single-step capture of biotinylated molecules such as DNA, RNA or protein from cell lysates or hybridizatio...
QuantumPlex is a bead kit for multiple analyte-detection research applications in flow cytometry. The beads may be analyzed with any standard cytometer and do not require the use of specialized softw...
... For the detection of ... (Pf HRP-2), P.vivax specific ... for the specific detection of ... malaria, differentiation of other malarial ...
192 Test Enzyme Immunoassay for the detection of Human IgG antibodies to all four forms of Malaria....
Medicine Products: