Navigation Links
NSAID Drug Therapy Fails to Ease Back Pain
Date:11/9/2007

Trial also found no benefit from spinal manipulation

FRIDAY, Nov. 9 (HealthDay News) -- Two widely used treatments for acute low back pain -- nonsteroidal anti-inflammatory drugs (NSAIDs) and spinal manipulation -- did not help patients in a carefully controlled study, Australian researchers report.

That's not especially surprising, American specialists said, because the evidence for their effectiveness has never been overwhelming. In fact, new recommendations for treating lower back pain take the lack of effectiveness of these treatments into account.

However, this is one of very few studies to provide solid documentation of what happens -- or doesn't -- with the treatments, the experts said.

"They just don't work better than placebo control," said Dr. Todd J. Albert, professor of orthopedic surgery and neurosurgery at Jefferson Medical College, who was not involved in the research. "But they are two common things that physicians do all the time. Patients come to a hospital feeling entitled to a treatment, and doctors feel they have to treat," he said.

The Australian study, done at the University of Sydney, included 240 people who had been treated with acetaminophen for low back pain without getting major relief. They were divided into four groups -- one getting the NSAID diclofenac (sold as Voltaren) at 100 milligrams per day and manipulative therapy, another getting the drug and a fake manipulative therapy, a third getting real manipulative therapy and a placebo drug, and the fourth getting a placebo drug and the fake manipulative therapy.

"Neither diclofenac nor spinal manipulative therapy gave clinically useful effects on the primary outcome of time to recovery," the researchers report in the Nov. 10 issue of The Lancet.

New guidelines just issued by the American College of Physicians and the American Pain Society already advise against general use of the two therapies, noted Dr. Daniel Mazanec, associate director of the Cleveland Clinic Center for Spinal Health.

"For this group of patients, with acute nonspecific low back pain with an average duration of nine days, the guidelines recommend the importance of staying active and [taking] relatively simple painkillers such as acetaminophen," Mazanec said.

Still, "this is the first study in a well-characterized group of patients to support the guidelines," he said.

The potential side effects of NSAIDs make avoiding them advisable if possible, Albert said. But one or another of them may still be used in individual cases, since different people may get some relief from one NSAID but not another, he said.

"There is individuality to response," he said.

Other NSAIDs include aspirin, ibuprofen (Advil, Motrin) and naproxen (Aleve).

While diclofenac did not speed the progression to recovery from pain, "that doesn't mean it should not be used, because it may make patients more comfortable along the way," Albert said.

Side effects of NSAID treatment in the study included gastrointestinal disturbances, dizziness and heart palpitations. However, the incidence of such side effects was about the same in the group getting the placebo drug treatment, the researchers noted.

More information

There's more on back pain at the U.S. National Library of Medicine.



SOURCES: Todd J. Albert, M.D., professor, orthopedic surgery and neurosurgery, Jefferson Medical College, Philadelphia; Daniel Mazanec, M.D., associate director, Cleveland Clinic Center for Spinal Health; Nov. 10, 2007, The Lancet


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Using coxibs and NSAIDs to treat osteoarthritis
2. Link Uncovered Between Benign Prostatic Hyperplasia and NSAIDs, Says Harvard Mens Health Watch
3. NSAIDs Protect Against Parkinsons Disease
4. Vision restoration therapy shown to improve brain activity in brain injured patients
5. HIV therapy in pregnancy-data support WHO recommendations
6. Family-based treatment more effective than supportive psychotherapy in treating bulimia
7. Trial to Test Gene Therapy for Angina in Women
8. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
9. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
10. Chemotherapy may be culprit for fatigue in breast cancer survivors
11. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NSAID Drug Therapy Fails to Ease Back Pain
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, ... remain in the eye of the beholder, according to experts who offered insights and ... Journal of Managed Care. For the full issue, click here . , For ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... ... fertility once they have been diagnosed with endometriosis. These women need a treatment ... also require a comprehensive approach that can help for preservation of fertility and ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June ... -based mobile pulmonary function testing company, is now able to ... devices developed by ndd Medical Technologies , Inc. ... done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ... , can get any needed testing done in the comfort of ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... Ill. , June 23, 2016  In a startling report ... are failing their residents by lacking a comprehensive, proven plan to ... a definitive ranking of how states are tackling the worst ... to only four states – Kentucky , ... Vermont . Of the 28 failing states, three ...
Breaking Medicine Technology: