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NIPPV linked to increased hospital mortality rates in small group of patients
Date:10/20/2011

PV, required subsequent placement on IMV," said Dr. Holguin, who also serves as the assistant director of the University of Pittsburgh Medical Center's Asthma Institute at the University of Pittsburgh School of Medicine. "It is notable that this finding is contrary to that found in the carefully monitored patient environment of clinical trials, where those transitioned from NIPPV to IMV did not have higher mortality than patients placed on IMV from the beginning."

Dr. Holguin added that the overall trend toward greater use of NIPPV was likely due to several factors, including clinical trials linking NIPPV with a decrease in hospital mortality, increased confidence in using NIPPV and the ability to use NIPPV outside of the intensive care unit.

"These results suggest that healthcare providers should continue to be aggressive with the use of noninvasive ventilation for patients with acute exacerbations, but definitely should intensively monitor sick patients, intervene early in the absence of improvement, and carefully examine if transitioning to IMV is in the interest of a patient with a poor prognosis," he said.


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Contact: Brian Kell
bkell@thoracic.org
212-315-6442
American Thoracic Society
Source:Eurekalert

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