Navigation Links
NIH study sheds light on how to reset the addicted brain
Date:4/3/2013

Could drug addiction treatment of the future be as simple as an on/off switch in the brain? A study in rats has found that stimulating a key part of the brain reduces compulsive cocaine-seeking and suggests the possibility of changing addictive behavior generally. The study, published in Nature, was conducted by scientists at the Intramural Research Program of the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and the University of California, San Francisco.

"This exciting study offers a new direction of research for the treatment of cocaine and possibly other addictions," said NIDA Director Dr. Nora D. Volkow. "We already knew, mainly from human brain imaging studies, that deficits in the prefrontal cortex are involved in drug addiction. Now that we have learned how fundamental these deficits are, we feel more confident than ever about the therapeutic promise of targeting that part of the brain."

Compulsive drug-taking, despite negative health and social consequences, has been the most difficult challenge in human drug addiction. NIDA researchers used an animal model of cocaine addiction, in which some rats exhibited addictive behavior by pushing levers to get cocaine even when followed by a mild electric shock to the foot. Other rats did not exhibit addictive responses.

The NIDA scientists compared nerve cell firing patterns in both groups of rats by examining cells from the prefrontal cortex. They determined that cocaine produced greater functional brain deficits in the addicted rats. Scientists then used optogenetic techniques on both groups of rats -- essentially shining a light onto modified cells to increase or lessen activity in that part of the brain. In the addicted rats, activating the brain cells (thereby removing the deficits) reduced cocaine-seeking. In the non-addicted rats, deactivating the brain cells (thereby creating the deficits) increased compulsive cocaine seeking.'/>"/>

Contact: Press Office
media@nida.nih.gov
301-443-6245
NIH/National Institute on Drug Abuse
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Angeles, CA (PRWEB) August 21, 2014 ... features in-depth information and reviews of some of the ... many others, is pleased to announce that it is ... the systems. For seniors who are on a fixed ... medical device, this announcement comes as very welcome news. ...
(Date:8/20/2014)... 20, 2014 Coolercovers.com, a division ... the availability of select products on Amazon.com ... aims to increase product availability and customer resources. ... of canvas covers for air conditioners and evaporative ... Rheem, Payne, Armstrong, Amana, Carrier, Trane, Mitsubishi, Goodman, ...
(Date:8/20/2014)... (PRWEB) August 21, 2014 Recently, UWDress.com, ... its new selection of birthday party dresses for ... cute items are well-designed and exquisitely handmade by experienced ... to 58 percent off. , The company’s new items ... zipper gowns, short knee length frocks, long elegant backless ...
(Date:8/20/2014)... 21, 2014 Top10BestSEOHosting.com is a ... about hosting products. It is headed by a ... The site offers research-based information and factual studies ... in the current market. , Recently, Top10BestSEOHosting.com ... that GoDaddy and Bluehost are the ...
(Date:8/20/2014)... 2014 Park Avenue Dental, a leading ... Sherman, a top graduate of the University of Detroit ... of its website through an ultra-informative blog focused on ... of parkavenuedentalfl.com, the blog page is chock full of ... material, instead concentrating on important dental care tips ...
Breaking Medicine News(10 mins):Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 2Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 3Health News:Air Conditioner Covers for Most A/C Units Now Available Online at Coolercovers.com and Amazon.com 2Health News:Air Conditioner Covers for Most A/C Units Now Available Online at Coolercovers.com and Amazon.com 3Health News:Cheap Birthday Party Dresses for Girls Now Available at UWDress.com 2Health News:New Reviews For Linux Web Hosting Suppliers Announced By Top10BestSEOHosting.com 2Health News:Park Avenue Dental Provides Dental Care Tips for World Wide Community on New Website Blog 2Health News:Park Avenue Dental Provides Dental Care Tips for World Wide Community on New Website Blog 3
... $35 Cost Per Metric Ton of CO2 ... Ten Percent Cut in Emissions Possible, PITTSBURGH, May ... to continue to move the United States toward a,mandatory ... Mellon University researchers provides the clearest picture yet of,the ...
... HILL Stretching exercises may be more effective at reducing ... who have already experienced the condition and who do not ... of North Carolina at Chapel Hill School of Nursing. ... up to 8 percent of pregnancies every year and is ...
... Cascal N.V. (NYSE: HOO ) ("the,Company"), a leading ... announced that it plans to present at the 3rd ... York Hotel &,Towers in New York City on Tuesday, ... Richer, Cascal,s Chief Executive Officer, will provide an,overview of ...
... are remarks by,Attorney General Michael B. Mukasey on the ... you, and good afternoon. I,m pleased to be here ... Justice Department is doing to,fight health care fraud. I,d ... Criminal Division, and everyone here for your hard,work., ...
... , , WEDNESDAY, May 28 (HealthDay News) -- Much like the ... to arouse the brain may end up being ignored in ... Hong Kong researchers who compared the amount of arousal in ... in children with a history of bedwetting to a control ...
... advise nursing women of any potential risks , , WEDNESDAY, ... Wednesday changes to the labels on prescription drugs that ... women, their fetuses or their newborns. , If ... and Drug Administration, would provide doctors and pharmacists with ...
Cached Medicine News:Health News:Establishing a Price for Carbon Emissions in the U.S. Would Spur Immediate Reductions in Energy Consumption and More Efficient Use of Power Generators, Study by Carnegie Mellon Researchers Shows 2Health News:Establishing a Price for Carbon Emissions in the U.S. Would Spur Immediate Reductions in Energy Consumption and More Efficient Use of Power Generators, Study by Carnegie Mellon Researchers Shows 3Health News:Stretching exercises may reduce risk of pre-eclampsia during pregnancy 2Health News:Prepared Remarks of Attorney General Michael B. Mukasey on the Justice Department's Efforts to Combat Healthcare Fraud Nationwide 2Health News:Prepared Remarks of Attorney General Michael B. Mukasey on the Justice Department's Efforts to Combat Healthcare Fraud Nationwide 3Health News:Brain May Ignore Bladder Signals, Causing Bedwetting 2Health News:Brain May Ignore Bladder Signals, Causing Bedwetting 3Health News:FDA Proposes New Drug Labels for Pregnant Women 2Health News:FDA Proposes New Drug Labels for Pregnant Women 3
(Date:8/20/2014)... ApolloDx™ today announced it will unveil and ... event at the company,s office in Salt ... The event, which will start at 10:00 a.m., will ... .    "We believe our mobile diagnostic ... , Co-Founder and Managing Partner of ApolloDx. In addition ...
(Date:8/20/2014)... WORTH, Fla. , Aug. 20, 2014  Glades Drugs, ... , is proud to announce its expansion into a ... , which will feature an 8,000-square-foot office space and state ... currently accepting applications for 100 open positions for the new ... at 4560 Lantana Road will serve as the chain,s corporate ...
(Date:8/20/2014)... Breathe , the fastest growing online sleep apnea shopping destination ... received more than 4.5 million unique page views since the start ... many people are finding our blog and reading our articles," said ... making sleep apnea more widely known and hope that people continue ... news , troubleshooting advice , and new product launches ...
Breaking Medicine Technology:Glades Drugs Moves to New Corporate Headquarters, 100 Open Positions 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 3Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 4
... that a new market research report is available in ... PharmaVitae Profile http://www.reportlinker.com/p0201761/Eli-Lilly--Co-PharmaVitae-Profile.html ... and forecast performance for Eli Lilly in the prescription ... and pipeline analysis and assessment of financial per ...
... Sept. 23 OmniComm Systems, Inc. (OTC: OMCM), ... EDC marketplace, today announced that Beardsworth, a full ... difficult therapeutic areas, has selected OmniComm,s AE Reporting ... Reporting is an advanced adverse event reporting and ...
Cached Medicine Technology:Reportlinker Adds Eli Lilly & Co.: PharmaVitae Profile 2Reportlinker Adds Eli Lilly & Co.: PharmaVitae Profile 3Reportlinker Adds Eli Lilly & Co.: PharmaVitae Profile 4Reportlinker Adds Eli Lilly & Co.: PharmaVitae Profile 5Reportlinker Adds Eli Lilly & Co.: PharmaVitae Profile 6Reportlinker Adds Eli Lilly & Co.: PharmaVitae Profile 7Beardsworth® Selects OmniComm Systems® AE Reporting System 2Beardsworth® Selects OmniComm Systems® AE Reporting System 3
... pumps deliver critical performance for all vacuum ... optimizes pump performance to suit all applications. ... convenient checking of proper oil levels at ... is designed to work with all Thermo ...
Produces vacuum pressures required for 96 well kits...
Variable Speed Pump...
Inquire...
Medicine Products: