Navigation Links
NIH scientists identify maternal and fetal genes that increase preterm birth risk
Date:2/4/2010

issues. The maternal and fetal genes that Dr. Romero and his colleagues identified regulate the amount of extracellular matrix in the uterus. The extracellular matrix of the uterine cervix and of the membranes containing the embryonic fluid are broken down at the beginning of labor.

To conduct the study, the scientists evaluated 190 genes and more than 700 DNA variants in samples from 229 women and 179 premature infants, and a large number of women who delivered at term. The study was conducted on a population of women in Chile. All of the women in the study were of Hispanic origin (of largely white and Native American backgrounds.). The study is one of the few to look at the genetic factors governing birth in an exclusively Hispanic population.

Infants who carried the DNA variant in the gene for the Interleukin 6 receptor were more likely to be born premature than those who did not. Interleukin 6 is produced by cells in response to infection and is involved in inflammation. In previous studies, Dr. Romero and his team found that high levels of Interleukin 6 in the amniotic fluid and in the fetal blood are associated with the beginning of premature labor.

Dr. Romero noted that molecules responsible for inflammation such as Interleukins 1 and 6 predate the human species and even mammals. He added that Interleukin 1-like molecules are even present in primitive organisms, such as sponges (which do not undergo labor). The primary function of these molecules is to fight infection. However, in most mammals, these molecules are not only used by the immune system to fight infection, but also play a role in triggering the onset of labor.


'/>"/>

Contact: Robert Bock
bockr@mail.nih.gov
301-496-5133
NIH/National Institute of Child Health and Human Development
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
2. Scientists Probe Sepsis Deadly Secrets
3. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
4. Scientists Develop Natural Protection for Stored Foods
5. Scientists detect presence of marburg virus in african fruit bats
6. Scientists Spot Brains Free Will Center
7. Scientists ID Likely Culprit in Popcorn Lung
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Scripps Research scientists shed new light on how antibodies fight HIV
10. Scientists, physicians present latest findings in personalized cancer treatment and prevention
11. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... 17, 2014 In a continuing effort ... Nile virus threats, Mosquito Shield of the South Shore ... with the Hanover Youth Athletic Association to treat area ... daily practices going until dusk, prime mosquito feeding time, ... athletes, coaches, and parents involved in outdoor athletic activities. ...
(Date:9/17/2014)... 2014 Stand Up for Heroes, New ... to the Theater at Madison Square Garden, Wednesday, Nov. ... Foundation (BWF) and New York Comedy Festival (NYCF), the ... veterans and their families. , The charitable event ... Oliver, Bruce Springsteen, Brian Williams and other surprise guests. ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 Health ... increase efficiency. Today, Pharmacy Healthcare Solutions, a wholly ... web-based analysis and forecasting tool that enables hospitals ... the impact of medications on improved patient outcomes. ... uses pharmacy purchase data to identify areas of ...
(Date:9/17/2014)... 16, 2014) A study led by St. Jude ... dose threshold below which male childhood cancer survivors ... study appears in September 17 edition of the ... which patients are at highest risk for reduced ... to eventually increase use of pre-treatment fertility preservation ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 MarijuanaStock.net, ... http://www.marijuanastock.net , recently launched a “Video” section that ... cannabis companies in the marijuana industry made available ... a website visitor is given access to numerous ... to marijuana-related businesses and the issues they face. ...
Breaking Medicine News(10 mins):Health News:Mosquito Shield of South Shore Again Partners with Hanover Youth Athletic Association 2Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 2Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 3Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 4Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 5Health News:Pharmacy Healthcare Solutions Launches TARxGET™ Reporting 2Health News:Pharmacy Healthcare Solutions Launches TARxGET™ Reporting 3Health News:Improved risk identification will aid fertility preservation in young male cancer patients 2Health News:Improved risk identification will aid fertility preservation in young male cancer patients 3Health News:MarijuanaStock.net Adds Business News Video Section to Their Website 2
... drilling, new energy technologies, science at the LHC, tests of gravity ... edge science will be featured in talks at this year,s April ... April 30 to May 3 at the Hyatt Hotel Orange County ... free of charge. Registration information can be found at the end ...
... be at increased risk of damage to the same brain ... by researchers at Washington University School of Medicine in St. ... that scientists have linked to neurological problems including Parkinson,s disease-like ... than 1 million workers who perform welding as a part ...
... the School of Public Health at the University of ... of depression may have long-term benefits. The data ... a longitudinal Canadian study, and showed depressed adults who ... depressed eight years later, compared to depressed adults who ...
... , WEDNESDAY, April 6 (HealthDay News) -- Long-term users ... damage, warns a new study. Brain scans showed an ... and a lower proportion of overall gray matter among long-term ... that people who use ecstasy can develop serious memory problems, ...
... THURSDAY, April 7 (HealthDay News) -- For American parents, doctors ... of children,s vaccines, a new study indicates. Researchers conducted ... and younger, and found that 76 percent said they trusted ... information about vaccine safety. Other sources trusted "a lot" ...
... (HealthDay News) -- A new report reveals that 98.8 percent ... to 64 with untreated alcohol abuse disorders don,t believe they ... nearly 6 million American adults with untreated alcohol dependence recognize ... to increase public awareness about adult problem drinking, how to ...
Cached Medicine News:Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 2Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 3Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 4Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 5Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 6Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 7Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 8Health News:Welders may be at increased risk for brain damage 2Health News:Treatment for depression a long-term solution 2Health News:Long-Term Ecstasy Users at Risk for Brain Damage, Study Warns 2Health News:Doctors Most Trusted Source of Vaccine Information, Study Finds 2Health News:Only 1.2% of Alcohol Abusers Know They Need Help: Report 2
(Date:9/17/2014)... 2014  Millions of people suffer from neck and arm ... Recently the FDA approved the launch of a clinical ... device developed by Spinal Kinetics, which may offer relief to ... arm pain. Hospital for Special Surgery (HSS), the number one ... New York City and in the ...
(Date:9/17/2014)... Texas , Sept. 17, 2014  Lightbeam ... Direct Accountable Care Organization (Physician Direct ACO) to ... their physicians in providing better care while reducing ... Physician Direct Accountable Care Organization ... Network Services (OPNS). The OPNS mission is to ...
(Date:9/17/2014)... COLUMBUS, Ohio , Sept. 17, 2014 /PRNewswire/ ... Riverside Radiology and Interventional Associates announced today ... Systems to enhance its image sharing capabilities ... case of any network failures. In addition, the ... to help navigate disparate PACS systems to more ...
Breaking Medicine Technology:Cervical Disc Clinical Trial for People with Neck and Arm Pain Set to Begin at Hospital for Special Surgery 2Physician Direct Accountable Care Organization Selects Lightbeam Health to Enable Better Care at a Lower Cost 2Physician Direct Accountable Care Organization Selects Lightbeam Health to Enable Better Care at a Lower Cost 3Dicom Systems' Innovative Software Provides Enhanced Imaging Sharing Capabilities, as Well as Connection Reliability in the Case of Network Failure 2Dicom Systems' Innovative Software Provides Enhanced Imaging Sharing Capabilities, as Well as Connection Reliability in the Case of Network Failure 3
... Health Solutions, Inc. (NYSE: MHS ) will webcast its Annual Meeting ...  The presentations by David B. Snow Jr. , chairman and CEO, and ... , , ... Investor Relations section at www.medco.com/investor . The webcast will be available for ...
... May, AllerAir is supporting Multiple Chemical Sensitivities and Chemical Injury ...   , , , ... chemical awareness tips and a $50.00 gift certificate available via ... articles will be dedicated to Multiple Chemical Sensitivities ...
Cached Medicine Technology:Medco Announces Webcast for Annual Meeting of Shareholders 2Multiple Chemical Sensitivities Are Real 2Multiple Chemical Sensitivities Are Real 3
... Bird and Cronin, Inc. ... of Patient Footwear, Orthopedic ... Care Products. Our products ... quality and available in ...
... Aspen® CTO combines highly effective immobilization of ... a level of comfort that makes it ... substantially progressive immobilization in going from a ... and then on to a four-post orthosis. ...
... Shoulder Immobilizer with Contoured ... Navy cotton sling with foam-padded ... body straps. Quick-release closure buckles. ... 35 covered abduction wedge to ...
The Humeral Stabilizing System is a terrific option for immobilization of stable humeral fractures, stablesupracondular fractures, and biceps/triceps repairs....
Medicine Products: