Navigation Links
NIH launches trial to evaluate anti-inflammatory treatment for preventing heart attacks, strokes, and cardiovascular deaths
Date:8/21/2012

An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health.

Inflammation, along with high blood pressure and high cholesterol, plays a major role in heart attack and stroke. The Cardiovascular Inflammation Reduction Trial (CIRT) will determine whether treatment with a drug specifically targeting inflammation reduces rates of cardiovascular events among adults who have had a heart attack within the past five years and who also have type 2 diabetes or metabolic syndrome. The trial will randomly assign participants to receive methotrexate given at 10 to 20 milligrams weekly for three to four years or a placebo. Methotrexate is an inexpensive generic drug commonly used at low doses to treat rheumatoid arthritis. It is also used at higher doses to treat certain forms of cancers such as leukemias and lymphomas.

"This trial could have global impact by potentially changing treatment recommendations for millions of individuals with heart disease," said Gary H. Gibbons, M.D., director of the NHLBI.

Each year, over 2 million people in the United States have heart attacks or strokes, and many of them die. "If this generic drug, which is already on the market at low cost, proves effective for reducing risk of heart attacks, stroke, or death, it has the potential for broad public health impact in saving lives and reducing disease," said Paul Ridker, M.D., M.P.H., an expert in inflammation biology as it relates to heart attack and stroke. Dr. Ridker, who will serve as principal investigator for CIRT, is the Eugene Braunwald Professor of Medicine at Harvard Medical School, and director of the Center for Cardiovascular Disease Prevention at the Brigham and Women's Ho
'/>"/>

Contact: NHLBI
NHLBI_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dallas Launches Insecticide Spraying Against West Nile Virus
2. Elsevier launches new journal: Performance Enhancement & Health
3. American Chemical Society launches 2012 edition of popular Prized Science video series
4. ASH launches multi-million-dollar grant program to support critical blood disease research
5. Oxford University Press launches Evolution, Medicine, and Public Health
6. Northwestern launches comprehensive program for patients with bicuspid aortic valve disease
7. LaStone Launches Merger with TIR Massage Stone To Further The Advancement of Massage Therapy Education in 2012
8. Washington Massage School Launches Private Practice Clinic
9. beyondblue Launches Depression & Anxiety website and Info Line for Men
10. Amirsys AnatomyOne Launches Today
11. Friends Life Care, a Pennsylvania Based Long-Term Care Provider, Launches VigR eMeetinghouse — An Interactive Online Community
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... Helix House, an Internet marketing firm that ... record demand for marketing services that take advantage of ... the country and throughout Arizona looking for innovative and ... turning to experienced Internet marketing firms like Helix House. ... features a dedicated and organized team of Internet marketers ...
(Date:8/27/2014)... August 27, 2014 Hastings and Hastings, ... greater Phoenix metropolitan area and all of Arizona is ... $160,000 on a $2 million settlement. This is ongoing ... those who have been injured through no fault of ... and time-consuming, however Hastings and Hastings is unrelenting as ...
(Date:8/27/2014)... 2014 According to market research report, ... Power Range (Micro, Low, Medium, High), Voltage (Low & ... Geography - Global Market Trends & Forecast to 2019” ... with an analysis and forecast of the market size. ... estimated $16.64 billion in 2014 to $22.73 billion by ...
(Date:8/27/2014)... 2014 Specialty Technical Publishers (STP) and ... Audit Protocol Consortium (IAPC) EHS audit protocol for Brazil ... the world use IAPC EHS audit protocols to understand ... collect, share, archive, and export audit findings in a ... prepared by AECOM in partnership with STP and focus ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 Main Street Dental ... announcing its advice on how long a toothbrush can be ... best oral care for teeth and gums. , “Replacing a ... fairly regular basis," says Dr. Harvey Schwartz, owner of Main ... every three to four months." , Dr. Schwartz explains that ...
Breaking Medicine News(10 mins):Health News:Helix House Reports Record Demand For Marketing Services That Take Advantage Of Social Media 2Health News:Helix House Reports Record Demand For Marketing Services That Take Advantage Of Social Media 3Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $166,700 On A Settlement Of $2,000,000 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $166,700 On A Settlement Of $2,000,000 3Health News:Variable Frequency Drives Market Worth $22.73 Billion by 2019 – New Report by MarketsandMarkets 2Health News:Specialty Technical Publishers and AECOM Publish Environmental, Health & Safety (EHS) Audit Protocol for Brazil (and the State of São Paulo) 2Health News:Specialty Technical Publishers and AECOM Publish Environmental, Health & Safety (EHS) Audit Protocol for Brazil (and the State of São Paulo) 3Health News:Specialty Technical Publishers and AECOM Publish Environmental, Health & Safety (EHS) Audit Protocol for Brazil (and the State of São Paulo) 4Health News:Main Street Dental Team, Unionville’s Most Innovative Dental Clinic, Advises on the Best Time to Replace a Toothbrush 2
... 2007 According to a study using a dynamic ... NASDAQ: SHPGY, TSX: SHQ) ulcerative colitis drug LIALDA (mesalamine) ... drugs active ingredient, 5-aminosalicyclic acid (5-ASA), is released over ... colon is the site of inflammation in ulcerative colitis. ...
... Humans may not be any more sensitive in detecting ... recently published in Journal of Vision, an online, free-access ... Ophthalmology (ARVO). , Dr Eric Hiris of St. Mary,s ... that although many papers on the subject begin with ...
... assistance,division of Recovery Resources Inc., is offering Cleveland-area ... October in,recognition of national Drug-Free Work Week (October ... effective drug free workplace program. The U.S. ... in an,effort to educate businesses about the importance ...
... LONDON, October 17 - With Photo ... Around the,World, Raising Awareness of Stroke and Funds for ... plc, and James Cracknell OBE,double Olympic gold medallist, today ... Stroke Association. The campaign aims to,highlight the positive benefits ...
... offered to 10,000 Medicare Choice PPO members at no additional ... ... 17 Effective January 1, 2008, Group,Health Incorporated (GHI) has announced that ... toll-free number to speak with,their own independent Personal Health Advocate (PHA) for ...
... cancer ... awareness walk, WASHINGTON, Oct. 17 In an effort ... of,water and a storage unit during the Annual Walk for Hope to Cure ... 2K or 5K walk or run,took place at the grounds of Cabin John ...
Cached Medicine News:Health News:LIALDA demonstrates prolonged release of mesalamine in an in vitro study using a simulated colon 2Health News:LIALDA demonstrates prolonged release of mesalamine in an in vitro study using a simulated colon 3Health News:AssistNow Offers Area Employers Complimentary Needs Assessment in Recognition of National Drug-Free Work Week 2Health News:James Cracknell Launches Siemens Stroke for Stroke Week 2Health News:James Cracknell Launches Siemens Stroke for Stroke Week 3Health News:James Cracknell Launches Siemens Stroke for Stroke Week 4Health News:GHI to Provide Independent Personal Health Advocate for Medicare Members 2
(Date:8/26/2014)... NORTH ANDOVER, Mass. , Aug. 26, 2014 ... and Eatontown, N.J ., is expanding.  ... & Fitness to form a new division, Acelleron Maternal Health ... to their clients by providing a full range of resources ... Vecchi has been named the director of maternal wellness. ...
(Date:8/26/2014)...  Royal Philips (NYSE: PHG, AEX: PHIA) introduces the ... to empower seniors to live independently while aging well. ... call center, the mobile app gives seniors 24-hour access ... Philips and the Global Social Enterprise Initiative (GSEI) ... 96 percent of senior respondents said it is important ...
(Date:8/26/2014)... 2014  Avanir Pharmaceuticals, Inc. (NASDAQ: ... first patient into a phase II study to ... for the adjunctive treatment of major depressive disorder ... of a combination of deuterium modified dextromethorphan and ... of people with MDD who remain depressed despite ...
Breaking Medicine Technology:Suzanne Vecchi Named Director of Newly Acquired Acelleron Maternal Health & Wellness 2Philips Lifeline introduces response app to connect seniors with access to help in the event of an emergency 2Philips Lifeline introduces response app to connect seniors with access to help in the event of an emergency 3Avanir Pharmaceuticals Announces Initiation of Phase II Study of AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 2Avanir Pharmaceuticals Announces Initiation of Phase II Study of AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 3Avanir Pharmaceuticals Announces Initiation of Phase II Study of AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 4Avanir Pharmaceuticals Announces Initiation of Phase II Study of AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 5Avanir Pharmaceuticals Announces Initiation of Phase II Study of AVP-786 for the Adjunctive Treatment of Major Depressive Disorder 6
... BEIJING , July 7 /PRNewswire-Asia-FirstCall/ -- Concord ... CCM ), operator of,the largest network of radiotherapy and ... has filed its annual report for the fiscal year ended, ... Securities and Exchange,Commission on June 30, 2010 . The ...
... HARBIN, China , July 6 /PRNewswire-Asia-FirstCall/ -- ... or the,"Company"), a leading developer, manufacturer and marketer of ... other,health and nutritional products in the People,s Republic ... the Global Hunter 2010 China Conference,on Tuesday, July ...
Cached Medicine Technology:Concord Medical Files 2009 Annual Report on Form 20-F 2Weikang Bio-Technology to Present at Global Hunter 2010 China Conference on July 13, 2010 2Weikang Bio-Technology to Present at Global Hunter 2010 China Conference on July 13, 2010 3
... Seal-Away CS and Alliance Catheter ... for the introduction of catheters ... sinus from a superior approach. ... Medical's outstanding peel-away introducer performance ...
... been a key participant in the area ... a decade. Previous Medtronic autotransfusion systems allowed ... as well as to determine requirements for ... plasma (PRP) for a small amount of ...
This unique hemostatic seal provides a simple option for beating heart CABG anastomoses, allowing you to use your own hand-suturing technique without the release of cerebral emboli associated with th...
... .018 Biliary Self-Expanding Stent System combines low-profile, high ... This .018" guide wire compatible stent system provides ... all diameters (5.0 - 10.0 mm). Now, with ... offered in five stent lengths (28, 38, 56, ...
Medicine Products: