Navigation Links
NIH grant to support Translational Research Center for PCOS

RICHMOND, Va. (May 12, 2008) The Virginia Commonwealth University School of Medicine has received a competitive grant totaling nearly $6 million from the National Institutes of Healths National Institute on Child Health & Human Development to examine polycystic ovary syndrome, a disorder of the endocrine system that affects as many as 5 million women.

Polycystic ovary syndrome, or PCOS, causes hormonal imbalances leading to irregular menstrual cycles, excess facial and body hair, weight gain and adult acne. Women with PCOS are at high risk for developing Type II diabetes and at increased risk for cardiovascular disease.

The five-year grant will support an interdisciplinary and translational research center in PCOS, making VCU one of only15 Specialized Cooperative Centers Program in Reproduction and Infertility Research (SCCPRIR) in the country.

This research program initiative expands the existing PCOS program at VCU, allowing interdisciplinary and collaborative studies with partnering institutions, and will enhance our ability to bring research discoveries from the laboratory bench quickly to the clinical care of women with PCOS, said John Nestler, M.D., vice chair of the Department of Internal Medicine and chair of the Division of Endocrinology and Metabolism at the VCU School of Medicine. Nestler, a pioneer in PCOS research, is the primary investigator for the project.

VCUs SCCPRIR program focuses on the use of genetics to identify risk for PCOS in an individual woman and pharmacogenomics, designed to identify the optimal treatment for an individual patient, he said.

The SCCPRIR is administered by the Reproductive Sciences Branch of the NICHD, and provides funding for a limited number of research centers in the reproductive sciences. The purpose of these centers is to provide an arena for multidisciplinary interactions among basic and clinical scientists interested in establishing high-quality programs in reproduction and infertility research. The centers also serve as national resources for the training and career development of new scientists electing to pursue research in high priority areas of reproduction and infertility research.

In the 1980s, Nestler was among the first scientists in the world to suggest that insulin was an important reproductive hormone. His pioneering work to induce ovulation through the use of such insulin-sensitizing drugs as metformin has led to the common use of metformin to treat infertility in women with PCOS. In 1998, in an article in the New England Journal of Medicine, Nestler's research team was the first to publish findings on the combination therapy of metformin and clomiphene to promote ovulation.


Contact: Sathy Achia Abraham
Virginia Commonwealth University

Related medicine news :

1. Brainfood Awarded $25,000 Grant from General Mills Foundation through DC Mayor Fentys New Health Communities Program
2. St. Davids HealthCare Granted the States Top Honor for Quality and Performance Excellence
3. NIH awards LIAI major grant to test safety of new smallpox treatment
4. International Diabetes Federation gives grant to Philippine diabetes education program
5. Hospitals in Louisiana and Mississippi to Receive More Katrina Recovery Grants
6. NBCHs Community Coalitions Health Institute Receives CDC Grant
7. Making the Outdoors Safer for Communities: the American Academy of Dermatology Announces 2008 AAD Shade Structure Program Grant Recipients
8. USDA Grants Organic Certification to Ayalas Herbal Water(TM)
9. Courage Center Receives $150,000 Grant From Minneapolis Foundation
10. SCAI awards 46 grants for interventional cardiology training fellowships
11. Inscent, Inc. Receives Federal Grant to Develop Honeybee Repellents
Post Your Comments:
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released ... understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture ... Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that is ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the ... published author, William Nowers. Captain Nowers and his wife, Millie, have six children, ... in the Navy. Following his career as a naval aviator and carrier pilot, ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 ... characterized by frequent cessation in breathing. Oral appliances can offer significant relief to ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... products to meet the demand of today’s consumer and regulatory authorities worldwide. From ... probiotic experts and tested to meet the highest standard. , These products ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare ... CPR training aide "cprCUBE" on Kickstarter. The device will ... during cardiac arrests with better efficiency compared to the ... offers real-time feedback on efficacy of the compression for ... campaign has a goal to raise $5,000. ...
(Date:10/2/2017)... 2, 2017  AllianceRx Walgreens Prime, the combined central ... and pharmacy benefit manager Prime Therapeutics LLC (Prime), today ... included the unveiling of new signage at its headquarters ... as at a few other company-owned facilities across the ... patients, some of whom will begin to see the ...
(Date:9/27/2017)... , Sept. 27, 2017  Commended for their devotion to ... awards. Ranked as number one in the South Florida Business ... in Inc. 5000 yearly list, the national specialty pharmacy has ... Armando Bardisa will soon be honored by SFBJ as ... Set to receive his award in October, ...
Breaking Medicine Technology: