Navigation Links
NIH grant to support Translational Research Center for PCOS

RICHMOND, Va. (May 12, 2008) The Virginia Commonwealth University School of Medicine has received a competitive grant totaling nearly $6 million from the National Institutes of Healths National Institute on Child Health & Human Development to examine polycystic ovary syndrome, a disorder of the endocrine system that affects as many as 5 million women.

Polycystic ovary syndrome, or PCOS, causes hormonal imbalances leading to irregular menstrual cycles, excess facial and body hair, weight gain and adult acne. Women with PCOS are at high risk for developing Type II diabetes and at increased risk for cardiovascular disease.

The five-year grant will support an interdisciplinary and translational research center in PCOS, making VCU one of only15 Specialized Cooperative Centers Program in Reproduction and Infertility Research (SCCPRIR) in the country.

This research program initiative expands the existing PCOS program at VCU, allowing interdisciplinary and collaborative studies with partnering institutions, and will enhance our ability to bring research discoveries from the laboratory bench quickly to the clinical care of women with PCOS, said John Nestler, M.D., vice chair of the Department of Internal Medicine and chair of the Division of Endocrinology and Metabolism at the VCU School of Medicine. Nestler, a pioneer in PCOS research, is the primary investigator for the project.

VCUs SCCPRIR program focuses on the use of genetics to identify risk for PCOS in an individual woman and pharmacogenomics, designed to identify the optimal treatment for an individual patient, he said.

The SCCPRIR is administered by the Reproductive Sciences Branch of the NICHD, and provides funding for a limited number of research centers in the reproductive sciences. The purpose of these centers is to provide an arena for multidisciplinary interactions among basic and clinical scientists interested in establishing high-quality programs in reproduction and infertility research. The centers also serve as national resources for the training and career development of new scientists electing to pursue research in high priority areas of reproduction and infertility research.

In the 1980s, Nestler was among the first scientists in the world to suggest that insulin was an important reproductive hormone. His pioneering work to induce ovulation through the use of such insulin-sensitizing drugs as metformin has led to the common use of metformin to treat infertility in women with PCOS. In 1998, in an article in the New England Journal of Medicine, Nestler's research team was the first to publish findings on the combination therapy of metformin and clomiphene to promote ovulation.


Contact: Sathy Achia Abraham
Virginia Commonwealth University

Related medicine news :

1. Brainfood Awarded $25,000 Grant from General Mills Foundation through DC Mayor Fentys New Health Communities Program
2. St. Davids HealthCare Granted the States Top Honor for Quality and Performance Excellence
3. NIH awards LIAI major grant to test safety of new smallpox treatment
4. International Diabetes Federation gives grant to Philippine diabetes education program
5. Hospitals in Louisiana and Mississippi to Receive More Katrina Recovery Grants
6. NBCHs Community Coalitions Health Institute Receives CDC Grant
7. Making the Outdoors Safer for Communities: the American Academy of Dermatology Announces 2008 AAD Shade Structure Program Grant Recipients
8. USDA Grants Organic Certification to Ayalas Herbal Water(TM)
9. Courage Center Receives $150,000 Grant From Minneapolis Foundation
10. SCAI awards 46 grants for interventional cardiology training fellowships
11. Inscent, Inc. Receives Federal Grant to Develop Honeybee Repellents
Post Your Comments:
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... ... ... crisis. Her son James, eight, was out of control. Prone to extreme mood shifts and ... him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife on ... say he was going to kill them. If we were driving on the freeway, ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... ... ... Comfort Keepers® of San Diego, CA is excited to announce they are ... drive cancer patients to and from their cancer treatments. Comfort Keepers provides quality ... and ongoing independence. Getting to and from medical treatments is one of the ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016 One of Australia,s successful ... of a new biotechnology company, Noxopharm Limited [ABN 50 608 966 ... and to list on the ASX. Noxopharm is a ... enter a Phase 1 clinical study later this year. ... of the biggest problems facing cancer patients - the ability of ...
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
Breaking Medicine Technology: