Navigation Links
NIH grant advances dentistry school's work on psychosocial stress
Date:11/6/2007

Every day, trauma centers throughout the country provide acute care to patients with intentional injuries. The focus is on treating the physical injury of the patients; there is precious little time for attending to the underlying risky behaviors that gave rise to the injury or to what its psychosocial aftereffects may be.

Vivek Shetty, an oral and maxillofacial surgeon at the UCLA School of Dentistry who treats patients with facial trauma, recently proposed that introducing technology to this scenario could lead to a better way to screen for and detect the psychological impact of injuries and thus unite the complementary skills of various health care providers to deliver comprehensive care to patients.

The National Institutes of Health found merit in this unique approach and agreed to fund Shetty's idea.

The UCLA School of Dentistry is among the first research institutions to receive a grant from the NIH's new Genetics, Environment and Health Initiative. Among other goals, the initiative seeks to develop new technologies to measure psychosocial stress and the use of addictive substances, both licit and illicit, in large-scale studies of diverse populations. The four-year, $1,876,920 award to Shetty, the grant's principal investigator, will culminate in the implementation of an innovative new tool that will provide rapid and reliable assessments of the stress response to trauma as evidenced in saliva.

Shetty's previous studies have shown that traumatic facial injury provokes an immediate, intense psychological response from the victim, and a significant number of patients manifest post-traumatic stress disorder-like symptoms even one year after the injury. Nevertheless, a busy trauma center is not the ideal setting for administering the detailed questionnaires that help identify related mental health issues, whether they exist before or develop after injuries.

For these reasons, Shetty felt it important to develop an effective transdisciplinary approach that sets the stage for early integrated case management and interventions across a broad range of allied specialties. If surgeons, nurses and social workers can easily identify at-risk patients who could benefit from psychological treatment and make the appropriate referrals for targeted interventions and follow-up care, they might be able to prevent further trips to the emergency room.

"A handheld salivary biosensor of stress could help health care providers treat not merely the physical injury but the whole person," said Shetty, a professor of oral and maxillofacial surgery at the UCLA School of Dentistry.

In recent years, the concept of using saliva as a reliable, noninvasive and highly informative diagnostic tool has come into its own. As the technology of salivary diagnostics improves, the idea of using a saliva-based expression of the individual stress response as the basis for point-of-use detection becomes a reality.

"Such a tool could have a profound impact on how we screen, triage and treat injured patients," Shetty said. "Enabling surgeons to rapidly assess the risk for future psychological and substance-use problems will set the stage for expanded, high-quality post-trauma care that is specific to the needs of each patient and incorporates appropriate mental health interventions."

For the past decade, the UCLA School of Dentistry has been a leader in the burgeoning field of salivary diagnostics research, which portends dramatic changes in the future of clinical diagnostics. Currently, the school's scientists are engaged in projects that use saliva to assess the risk of dental caries; create smart, targeted antibiotics that preserve beneficial flora; and diagnose various systemic illnesses, from oral and breast cancer to autoimmune diseases and diabetes.

The research currently being conducted by Shetty builds on research on collaborative-care interventions made possible by an ongoing five-year, $3.8 million grant from the National Institute on Drug Abuse.

"UCLA takes great pride in its researchers operating at the cutting-edge of salivary diagnostics. Our objective is to translate the discoveries we make in the laboratory into new tools that will transform the standard of clinical care," said No-Hee Park, dean of the UCLA School of Dentistry. "Dr. Shetty's research brings together the fields of surgery, biostatistics, biomedical engineering and psychology to expand the use of saliva as a diagnostic tool beyond physical illness to include psychological illness."


'/>"/>

Contact: Sandra Shagat
sshagat@dentistry.ucla.edu
310-206-0835
University of California - Los Angeles
Source:Eurekalert

Related medicine news :

1. UVa researcher awarded $3.6 million grant to fight drug-resistant bacteria
2. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
3. $21.8 Million NIH Grant for Fragile X Research
4. Bioniche Receives $2 Million Government Grant For Market Development Related to its E. coli O157:H7 Cattle Vaccine
5. Boston University School of Medicine researcher recipient of Memory Ride Grant
6. RAND researchers offer options to improve immigrant health care quality, access
7. Pennsylvania Department of Aging Receives Grant to Improve Alzheimers Support
8. CAS Medical Systems, Inc. Awarded $2.8 Million Grant by National Institutes of Health
9. NIH awards Einstein multimillion dollar grant to extend studies of exceptional longevity
10. Johns Hopkins receives $100 million grant to speed research from clinic to community
11. Major grant advances UWs clinical and translational research enterprise
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... , ... May 02, 2016 , ... According to an ... one in four girls are sexually abused before the age of 18. Of those ... to tell her story and others. , In her new book, Lyah! Lyah! ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... urgent care facilities designed to automate and improve the rapid diagnosis, triage and ... is demonstrating their platform, application, and mobile experience for the first time at ...
(Date:5/2/2016)... ... ... Dr. Jonathan Kulbersh of Carolina Facial Plastics isn’t surprised that Charlotte, NC, the city where ... 5 US Cities with the Highest Plastic Rates .” The other cities that made ... calculated using a survey by RealSelf and combining that data with the number ...
(Date:5/2/2016)... ... ... For many artists, the act of blending paint is based on intuition ... , Using the new, highly precise METTLER TOLEDO ML204T balance to weigh and ... to his works. What’s more, it has allowed him to recreate these shades and ...
(Date:5/2/2016)... ... May 02, 2016 , ... One of Hollywood’s best kept secrets for ... & Laser Center, in Milford, Penn. “Patients with busy lives want noninvasive options for ... and go home or back to work without having to wear recovery garments or ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016 , Net Sales of $1.90 billion ... the prior year period, and an increase of 1.2% on ... EPS for the first quarter were $0.52 reported, a decrease ... an increase of 29.9% over the prior year period ... guidance for 2016 Zimmer Biomet Holdings, Inc. (NYSE ...
(Date:4/28/2016)... April 28, 2016  ValGenesis, Inc., the ... Solutions (VLMS) today announced that a prominent ... sufferers of chronic kidney failure has selected ... their corporate validation process. The global medical ... solution to manage their validation processes electronically. ...
(Date:4/27/2016)... 27, 2016 ... in Zürich gab Strekin AG den Start ... zur Erhaltung des Resthörvermögens von Patienten, denen ... die umfassende Phase-II-Doppelblindstudie mit Placebo-Kontrollgruppe werden momentan ... wird während der Operation direkt ins Mittelohr ...
Breaking Medicine Technology: