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NIH-funded twin study finds occupational chemical exposure may be linked to Parkinson's risk
Date:11/13/2011

d have also demonstrated that TCE causes neurodegeneration in animal models.

The analysis described in this report expands on preliminary findings presented at the 2010 American Academy of Neurology meeting. The new paper quantifies the individuals' exposures to the chemicals in terms of successive years and cumulative exposure over their lifetime.

Dr. Tanner notes that while the association between chemical exposure and Parkinson's is strong, one limitation of the research is the small number of individuals studied. "It will be important to replicate these results in additional populations with well-characterized exposure histories," she commented.

Wendy Galpern, M.D., Ph.D., program director at NINDS, agreed that replication of these results is necessary. "This epidemiologic study is a noteworthy addition to our growing understanding of the association between environmental exposures and Parkinson's disease," Dr. Galpern said. "The identification of specific chemicals linked to this neurodegenerative disorder may have implications for disease prevention and an improved understanding of how Parkinson's develops."


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Contact: Nicole Garbarini
nindspressteam@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke
Source:Eurekalert

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