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NIH expands study to better understand kidney disease progression
Date:7/29/2013

Researchers from the Chronic Renal Insufficiency Cohort (CRIC) study are embarking on another five years of work to identify risk factors for progression of early stage chronic kidney disease (CKD), better understand the importance of reduced kidney function in older persons, and learn what role CKD may play in other illnesses that require hospitalization. CRIC is supported by the National Institutes of Health.

A major goal of the next five years is to recruit 1,500 people to the existing group of nearly 4,000 study participants. According to Dr. Harold Feldman, the principal investigator of the study's Scientific and Data Coordinating Center at the University of Pennsylvania, Philadelphia, this additional time will allow researchers to collect more data needed to explore and build upon findings compiled over the past 10 years, and examine in much greater detail the broad range of illnesses experienced by people with CKD.

"The original volunteers have aged since the study began. By extending the study, we're able to look more closely at an older population a crucial time since most people who develop kidney failure that requires dialysis or a kidney transplant do so in their early 60s," said Dr. Robert Star, director of the Division of Kidney, Urologic, and Hematologic Diseases at NIH's National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). "Studying older individuals with CKD is an area of considerable interest, so unlike the original cohort where participants were broadly aged -- between 21 and 74 years at study entry -- those invited to join now will be between the ages of 45 and 79."

Dialysis is a treatment to filter wastes and excess fluid from the blood, a task normally performed by the kidneys. Most people with kidney failure are attached to a dialysis machine for three to four hours at a time, three times per week.

Another important feature of the new study participants is that they will hav
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Contact: Bill Polglase
NIDDKMedia@mail.nih.gov
301-496-3583
NIH/National Institute of Diabetes and Digestive and Kidney Diseases
Source:Eurekalert

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