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NIH awards WSU researcher $1.39M to study chromatin's role in cell division
Date:8/16/2011

bitors, or HDIs. To refine HDIs, Pile will uncover the mechanisms of the target, HDAC chromatin modifiers. She will test a particular HDAC called Swi-independent SIN3 and determine whether SIN3 does, in fact, regulate cell growth and multiplication and, if so, how it affects deacetylation and gene repression.

"Inhibiting HDACs, the agents that fuel unregulated cell division, is anticipated to be an effective approach to preventing cancer progression," said Pile.


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Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

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