Navigation Links
NIH awards La Jolla Institute $18.8 million for major infectious disease study
Date:12/17/2009

asures a major public health concern.

For the malaria component, Dr. Sette and his research team will work with Denise Doolan, principal investigator on the malaria contract, and her team at the Queensland Institute of Medical Research in Australia, who are collecting blood samples from people exposed to the disease in Papua New Guinea, in collaboration with colleagues at the Papua New Guinea Institute for Medical Research.

Dr. Sette's team will provide key epitope information that the Queensland group can use in testing the blood samples. "We've looked at the malaria genome and have made bioinformatics predictions on which epitopes we think the immune system may recognize in malaria," said Dr. Sette. "Since the Queensland researchers are using blood samples from people previously infected, their immune systems' will have "memory" of the malaria parasite and will react to synthesized epitope pieces from it. It will become apparent, based on various body indicators, which epitopes triggered a defensive reaction from the immune system. We think this will provide some very exciting data that we hope may be useful in developing a first-ever malaria vaccine."

Institute researchers used the expansive resources of the Immune Epitope Database (IEDB), a major public health tool developed and hosted by the La Jolla Institute under a contract with the NIAID, to develop the malaria epitope predictions. The IEDB contains epitope data on a multitude of diseases, including malaria.

Regarding the dengue virus study, Dr. Sette said the Institute's research will be propelled by key advances in animal modeling made by researcher Sujan Shresta, Ph.D., who is co-investigator on the dengue study. In 2008, Dr. Shresta developed the world's first dengue virus mouse model showing key aspects of human infection. "For a long time, the central question in the field was, "Do the T cells protect or do they contribute to dengue virus disease?'" sai
'/>"/>

Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5

Related medicine news :

1. The Venza Group Received Top Honors at the American Society of Training & Development (ASTD) eLearning Excellence Awards Ceremony Held on December 10, 2009
2. BaylorHealth.com Wins National Healthcare Website Awards
3. Ascension Health Hospital Awards Streamline Health Contract to Ensure OSHA Compliance
4. The Kenneth Rainin Foundation Awards $457,000 in Grants to Support Dance, Theater, Film and Early Literacy in the San Francisco Bay Area
5. Tipping Point Community Announces $1 Million Gift at Third Annual Awards Breakfast
6. Wellness Manufacturer Wins Two 2009 American Spa Awards
7. CareTech Solutions Web Clients Earn Top Recognition in the Tenth Annual eHealthcare Leadership Awards Competition
8. Henninger Media Services Wins 9 TIVA Peer Awards
9. Arthritis Foundation Bestows Highest National Awards
10. CS3 Technology Announces Annual Employee Awards
11. ILS Technology and Customer ASML Recipients of Industry Recognition Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... that make energy to keep cells alive is a ... drug-resistant forms of cancer source of a serious ... a new study published in the journal ACS ... explain that doxorubicin and other common forms of chemotherapy ... cancer cells. Cancer cells divide and multiply faster than ...
(Date:5/22/2013)... Center at Hackensack University Medical Center, one of the ... cancer experts, for presentation and discussion of the latest ... in oncology, on Friday, June 7 from 7:00am to ... of the nation,s top immunology experts to review the ... both in solid and liquid tumors," said Andre Goy ...
(Date:5/22/2013)... 22, 2013 Peak Solar introduces unique, ... targeted to help potential customers make informed buying choices. ... to ensuring customer satisfaction is to give them the ... taken this advice to heart. Solar training seminars will ... implementation of different solar kits . , Poised ...
(Date:5/22/2013)... 22 (HealthDay News) -- Children and teens exposed to ... to develop cancer, according to a large, long-term study. ... group of 10,000 young people who each had one ... expected to occur within 10 years, according to researchers ... should carefully weight the risks to patients when making ...
(Date:5/22/2013)... the gene p53 turns off cancer. However, when existing drugs boost ... challenge. A study published in the journal Cell Reports ... reactivation create more of the protein p21 than the protein PUMA; ... first time, the current study shows a handful of genes that ... most commonly mutated cancer genes. Tumors turn it off and then ...
Breaking Medicine News(10 mins):Health News:Progress after recent breakthrough which opened new chapter in anti-cancer cell therapies 2Health News:Online Solar Training Seminars Aimed at Informing Consumers 2Health News:Children Who Have CT Scans May Face Higher Cancer Risk 2Health News:Study details genes that control whether tumors adapt or die when faced with p53 activating drugs 2
... -- There,s more evidence that use of the oral contraceptive ... some women experience during their period. Some previous research, ... could help women with painful periods, but a 2009 review ... such a conclusion. The new findings, from a Swedish ...
... MD Jan. 16, 2012 Listen up, pedestrians wearing ... you? Many probably can,t, especially young adult males. ... tripled in six years, according to new research from the ... Maryland Medical Center in Baltimore. In many cases, the ...
... Gordon HealthDay Reporter , TUESDAY, Jan. 17 (HealthDay News) ... American children are obese, new government reports show. That,s the ... years, those rates have remained roughly the same. "The stabilization ... this is not just the U.S. It,s happening all over the ...
... 17, 2012) Researchers at Columbia University Medical Center ... events that give rise to a type of esophageal ... the United States. The findings, published online today in ... origin and development of this deadly cancer and its ...
... the first time ever, stem cells from umbilical cords have ... lead to new treatment options for spinal cord injuries and ... "This is the first time this has been done ... Central Florida bioengineer and leader of the research group, whose ...
... HealthDay Reporter , TUESDAY, Jan. 17 (HealthDay News) ... but dissolvable, smokeless tobacco products aren,t for kids. The ... three-day U.S. Food and Drug Administration meeting this week. ... tobacco. These products are not stop-smoking aids. Instead, they are ...
Cached Medicine News:Health News:'The Pill' Can Help Ease Period Pain, Study Finds 2Health News:University of Maryland study: Headphone-distracted pedestrians face death, serious injury 2Health News:University of Maryland study: Headphone-distracted pedestrians face death, serious injury 3Health News:Americans Aren't Getting Any Skinnier 2Health News:Americans Aren't Getting Any Skinnier 3Health News:Study reveals origins of esophageal cancer 2Health News:Study reveals origins of esophageal cancer 3Health News:A first: Brain support cells from umbilical cord stem cells 2Health News:A first: Brain support cells from umbilical cord stem cells 3Health News:FDA to Weigh Safety of Tobacco Lozenges, Strips 2Health News:FDA to Weigh Safety of Tobacco Lozenges, Strips 3
(Date:5/22/2013)... , May 22, 2013 JenaValve Technology, Inc., a ... implantation (TAVI) systems for the treatment of aortic valve disease, ... enaValve Eval U ation of Long Term P erformance ... E vere Ao R tic Stenosis (JUPITER) Registry at EuroPCR ... registry to evaluate five-year long term safety and effectiveness of ...
(Date:5/22/2013)... and CAESAREA, Israel , May ... , New clinical data presented from the DEFLECT-I study ... Device reduces brain lesion volume during TAVR (Transcatheter Aortic ... Keystone Heart Scientific Advisory Board announces consensus on ... rising regarding the importance and need for cerebral protection ...
(Date:5/22/2013)...  The Lupus Research Institute (LRI) today is hosting ... for lupus nephritis, a serious kidney complication of lupus ... launched a new international alliance of researchers specializing in ... More than 50 of the world,s top ... focus on two critical questions: 1) Which new medicines ...
Breaking Medicine Technology:First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 2First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 3First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 4New Clinical Data Presented at EuroPCR Demonstrates that TriGuard Reduces Brain Lesion Volume during TAVR 2New Clinical Data Presented at EuroPCR Demonstrates that TriGuard Reduces Brain Lesion Volume during TAVR 3New Clinical Data Presented at EuroPCR Demonstrates that TriGuard Reduces Brain Lesion Volume during TAVR 4Lupus Research Institute Hosts First International Conference to Advance New Treatments for Lupus Nephritis 2
... The only portable 36/70 static/kinetic/multi-color perimeter that ... room and costs only slightly more than ... perimeter,The Centerfield automatically performs static and kinetic ... to 70 with a fixation shift. Offers ...
The new TOPCON 8800 Series of auto refractors and auto kerato-refractors satisfies the needs of today's demanding eyecare practice !...
The perfect tool to prepare for in-service or licensing exams, for recertification, or for use as a clinical refresher....
... Sun Med TruFlow™ Oxygen flowmeter with a ... warranty covering calibration and manufacturing defects. A ... meet most needs. Also available with all ... power take-off and double unit configurations. Our ...
Medicine Products: