Navigation Links
NIH awards $8 million to UT Southwestern to study metabolism, obesity-related inflammation
Date:9/14/2010

DALLAS Sept. 14, 2010 An $8 million grant from the National Institutes of Health will enable UT Southwestern Medical Center to investigate how fat tissue "talks" to the brain and the liver to promote inflammation-related disorders such as diabetes, heart disease and obesity.

The five-year grant takes advantage of expertise across the UT Southwestern campus, including faculty in the Touchstone Center for Diabetes Research, the division of hypothalamic research, and the departments of molecular genetics, internal medicine, and pharmacology.

"We're excited about tackling the complexity of how adipose [fat] tissue, the brain and the liver talk to each other and how this cross talk affects metabolism and inflammation," said Dr. Philipp Scherer, director of the Touchstone Center and principal investigator of the new project. "Getting this grant validates that the UT Southwestern metabolism group is doing state-of-the-art science."

In 2007, the Task Force for Obesity Research at UT Southwestern (TORS) received a $22 million NIH grant to enhance the institution's groundbreaking obesity research.

Dr. Scherer said that while there is clearly synergy with the TORS grant, this new effort is unique because it is specifically focused on phenomena related to inflammation, considered an underlying cause of metabolic disorders in humans.

"We're especially interested in understanding how the brain and the liver influence inflammation and how inflammation influences metabolism within other organs. Those are just a few of the questions our team plans to tackle," Dr. Scherer said.

Large fat cells are a particular area of focus, Dr. Scherer said, because they typically lead to increased cell death and systemic insulin resistance. Under normal circumstances, fat cells continue to grow until the extracellular matrix they've built around themselves is so strong that it's no longer flexible. Once that happens, the cells become
'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. NSF awards stem cell bio-manufacturing research and education program to Georgia Tech
2. Penns Positive Psychology Center awards $2.9 million for research
3. Susan G. Komen awards Case Western Reserve nearly $500,000 to study breast cancer in older women
4. NIH awards Scripps Florida scientists $2.3 Million to develop drug addiction treatments
5. AOSSM presents prestigious research awards at annual meeting
6. Solar Eclipz's Portable Umbrella And Canopy Curtain, Called The ezShade, Wins Coveted Outstanding Product Award From Disney Owned iParenting Media Awards
7. Outstanding high school students receive AGA Foundation 2010 Student Research Fellowship Awards
8. Damon Runyon Cancer Research Foundation awards $3.1M to 8 top young clinical investigators
9. Parkinsons Disease Foundation announces research awards totaling $1.2 million
10. Nominations Wanted for Vascular Disease Foundation President's Awards
11. Dorland Health People Awards Accepting Entries through Friday, June 25, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Biology and Medicine a multidisciplinary research team ... in the Institute of Genomic Biology (IGB) on ... describe their recent work on subcellular redox homeostasis. ... functions including energy metabolism, signaling, and transcriptional processes. ... cellular behavior, redox status has been recognized as ...
(Date:4/17/2014)... Pediatrician-in-Chief Jon McCullers, MD, was recently invited to ... Nature Reviews Microbiology , one of the ... world-renowned infectious disease specialist, and chair of the ... Health Science Center, analyzed the epidemiology and microbiology ... pandemics, as well as more recent 2009 novel ...
(Date:4/17/2014)... that as many as 10 million older Americans suffer ... and isolation. , However, new research a project ... Americans for six years found that Internet use ... by more than 30 percent. , "That,s a very ... professor of telecommunication, information studies and media who led ...
(Date:4/17/2014)... BostonResearchers from Boston University School of Medicine (BUSM) ... alcohol consumption in an experimental model. The findings, ... and Alcohol Abuse , may lead to more ... alcohol is one of the leading causes of ... significant negative economic impact by limiting the productivity ...
(Date:4/17/2014)... led by Cesar A. Arias, M.D., Ph.D., at The ... has identified a new superbug that caused a bloodstream ... the April 17 issue of The New England ... part of a class of highly-resistant bacteria known as ... a major cause of hospital and community-associated infections. The ...
Breaking Medicine News(10 mins):Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Internet use can help ward off depression among elderly 2Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2Health News:New MRSA superbug emerges in Brazil 2
... Blue Shield of Minnesota has received three awards for excellence from the ... management programs. The awards are in recognition of Blue Cross, performance in ... Cross, disease management efforts improved quality of care in: , , ... , asthma , ...
... Mich., Feb. 9 my1HIE and ... association with the my1HIE(SM) health information exchange. ... and participate in myWorkspace(SM), the physician web portal, ... by physicians for physicians and under development with ...
... SOUTHBOROUGH, Mass., Feb. 9 Throughout February, Kaz, ... is marking its second annual "National Care About ... other organizations such as the National Parent Teacher ... ), Honeywell Home Comfort Products is working to ...
... SAN JOSE, Calif., Feb. 9 VNUS(R) Medical,Technologies, Inc. ... medical devices for,the minimally invasive treatment of venous reflux ... 21st Annual OC Growth Stock Conference, to be,held February ... Dana Point, California.,The management speaker will be Peter Osborne, ...
... SSNMR, is a valuable tool to image and ... biomolecules. But the imaging process is time-consuming and ... study. , Yoshitaka Ishii, associate professor of chemistry ... he has found a quicker and more efficient ...
... beach, boosts well-being, study suggests, , , MONDAY, Feb. 9 ... can,t buy happiness, purchasing life experiences instead of material ... In a study that asked more than 150 older ... make them happy, researchers found that people were more ...
Cached Medicine News:Health News:Blue Cross Receives Disease Management Awards 2Health News:Blue Cross Receives Disease Management Awards 3Health News:Huron Valley Physicians Association to Participate with my1HIE 2Health News:Huron Valley Physicians Association to Participate with my1HIE 3Health News:Honeywell Home Comfort Products' Second Annual 'National Care About Your Indoor Air' Month 2Health News:Honeywell Home Comfort Products' Second Annual 'National Care About Your Indoor Air' Month 3Health News:New technique boosts protein NMR imaging speeds 2Health News:Experiences Bring More Joy Than Possessions Do 2Health News:Experiences Bring More Joy Than Possessions Do 3
(Date:1/14/2014)... Pa. , Jan. 14, 2014 Dynamic Healthcare Services, ... announced today that it acquired Progressive Home Medical Equipment, Inc. ... 7, 2014. The terms of the acquisition were not disclosed. ... equipment ("DME") company providing a wide range of sleep, mobility, ...
(Date:1/14/2014)... Critical Care, a LifeCentre partner practice, located at 165 Fort Evans ... in Loudoun County to receive a small ... Barnes , Medical Director, is a well-seasoned veterinarian of more than ... are avid scuba divers. "As altitude skiers and hikers, we recognize ...
(Date:1/14/2014)... Jan. 14, 2014 NineSigma , Inc., the ... Innovation Leadership Summit , May 14-16, 2014 at ... Cleveland Ohio . This is ... committed to breakthrough achievements through open innovation. Participants will ...
Breaking Medicine Technology:Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 2Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 3Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: