Navigation Links
NIH awards $8 million to UT Southwestern to study metabolism, obesity-related inflammation
Date:9/14/2010

DALLAS Sept. 14, 2010 An $8 million grant from the National Institutes of Health will enable UT Southwestern Medical Center to investigate how fat tissue "talks" to the brain and the liver to promote inflammation-related disorders such as diabetes, heart disease and obesity.

The five-year grant takes advantage of expertise across the UT Southwestern campus, including faculty in the Touchstone Center for Diabetes Research, the division of hypothalamic research, and the departments of molecular genetics, internal medicine, and pharmacology.

"We're excited about tackling the complexity of how adipose [fat] tissue, the brain and the liver talk to each other and how this cross talk affects metabolism and inflammation," said Dr. Philipp Scherer, director of the Touchstone Center and principal investigator of the new project. "Getting this grant validates that the UT Southwestern metabolism group is doing state-of-the-art science."

In 2007, the Task Force for Obesity Research at UT Southwestern (TORS) received a $22 million NIH grant to enhance the institution's groundbreaking obesity research.

Dr. Scherer said that while there is clearly synergy with the TORS grant, this new effort is unique because it is specifically focused on phenomena related to inflammation, considered an underlying cause of metabolic disorders in humans.

"We're especially interested in understanding how the brain and the liver influence inflammation and how inflammation influences metabolism within other organs. Those are just a few of the questions our team plans to tackle," Dr. Scherer said.

Large fat cells are a particular area of focus, Dr. Scherer said, because they typically lead to increased cell death and systemic insulin resistance. Under normal circumstances, fat cells continue to grow until the extracellular matrix they've built around themselves is so strong that it's no longer flexible. Once that happens, the cells become
'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. NSF awards stem cell bio-manufacturing research and education program to Georgia Tech
2. Penns Positive Psychology Center awards $2.9 million for research
3. Susan G. Komen awards Case Western Reserve nearly $500,000 to study breast cancer in older women
4. NIH awards Scripps Florida scientists $2.3 Million to develop drug addiction treatments
5. AOSSM presents prestigious research awards at annual meeting
6. Solar Eclipz's Portable Umbrella And Canopy Curtain, Called The ezShade, Wins Coveted Outstanding Product Award From Disney Owned iParenting Media Awards
7. Outstanding high school students receive AGA Foundation 2010 Student Research Fellowship Awards
8. Damon Runyon Cancer Research Foundation awards $3.1M to 8 top young clinical investigators
9. Parkinsons Disease Foundation announces research awards totaling $1.2 million
10. Nominations Wanted for Vascular Disease Foundation President's Awards
11. Dorland Health People Awards Accepting Entries through Friday, June 25, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... According to new market research ... Food & Beverage, Personal care & Pharmaceutical) & ... Electronics, Textile) & Geography - Global Trends & ... polylactic acid markets and segments with analyses and ... on their sub-segments, in terms of value and ...
(Date:8/21/2014)... San Luis Obispo, CA (PRWEB) August 21, 2014 ... July/August edition of Current Pedorthics, a bi-monthly publication of the ... the field of pedorthics. , Bunion Bootie ... as an alternative solution for bunion sufferers and their pain. ... be worn in nearly any shoe to eliminate the friction ...
(Date:8/21/2014)... WA (PRWEB) August 21, 2014 While ... Grant, found it hard to stay focused on his ... and mosquitoes. The constant whine, slapping and continual need ... researching innovative methods to stay protected from insects while ... successful career in the Financial Services/Investment Banking Industry, decided ...
(Date:8/21/2014)... 2014 Atlantic Information Services, Inc. (AIS) ... News and The AIS Report on Blue Cross & ... Blue Shield Association or its member companies) — is ... in AIS’s Management Insight Series. Bundled Payment Models: ... two insurers — Horizon Healthcare Services, Inc. and Arkansas ...
(Date:8/21/2014)... 2014 AttorneyOne.com, a recognized authority on ... information from the FDA on Dianeal Low Calcium ... announced on August 15, that two lots of Dianeal ... 5000mL (Ambu-Flex II), by Baxter International Inc., are ... , The reason for the recall is the ...
Breaking Medicine News(10 mins):Health News:Lactic Acid Market Worth $3,577.5 Million & Polylactic Acid Market Worth $4,840.1 Million by 2019 – New Report 2Health News:Lactic Acid Market Worth $3,577.5 Million & Polylactic Acid Market Worth $4,840.1 Million by 2019 – New Report 3Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 3Health News:Financial VP Fights Pesky Bugs with Launch of Biteback Sports Insect Shield® Golf Apparel 2Health News:New AIS Report Highlights Two Case Studies of Bundled Payment Models 2Health News:Dianeal Low Calcium (2.5mEq/L) Peritoneal Dialysis Solution with 2.5% Dextrose 5000mL (Ambu-Flex II) Recalled: AttorneyOne Monitors and Keeps Consumers Informed 2
... humans are genetically more suited to being vegetarians than meat-eaters ... conference by more then 300 leading scientists from New Zealand ... finding a cure for cancer is also under discussion at ... Convener of the conference says the finding that a human ...
... drawer, the time-honored lessons of helping organize one’s clothes learned ... to encode such categories as socks, shirts, or any other ... research from Harvard Medical School (HMS) investigators has identified an ... report in the advanced online Nature that they have identified ...
... Palmerston North high school, 500 will undergo testing this week ... students will be tested in the coming weeks. ... and laboratory tests have now confirmed the boy has tuberculosis. ... and parents revealed exposure to the infecting bacteria. The remaining ...
... skin lightening products are available over the counter but the ... over the counter skin lighteners that contain hydroquinone because studies ... causing. ,Dermatologist, Dr. Mathew Avram, of Massachusetts General Hospital ... here. I think they haven't seen the data to show ...
... that studies that were being conducted towards pest control ... ,Researchers from the University of California, have stated ... been identified by researchers who were initially looking for ... for people suffering from arthritis and other inflammatory diseases. ...
... present in almost every medicine cabinet, may help in easing ... Clinic.// ,Aspirin is known to help in the ... of cancer along with headaches. The researchers say that now ... to have been connected with enlarged prostates. ,It ...
Cached Medicine News:Health News:Brain's Filing System Uncovered 2Health News:Brain's Filing System Uncovered 3Health News:Pest Control research Leads to Pain Control Discovery 2Health News:Pest Control research Leads to Pain Control Discovery 3
(Date:8/20/2014)... -- Research and Markets  has announced the addition of ... their offering. Global Market Report of Pralmorelin ... and regionally ( Europe , Asia ... Latin America etc.). It captures Pralmorelin market trends, ... on three primary areas; manufacture methods & technology development, market ...
(Date:8/20/2014)... Ariz. , Aug. 20, 2014   ... the  Roche  Group, today announced that its VENTANA ... CE marked in the European Union for routine ... The system, consisting of VENTANA Virtuoso software coupled ... VENTANA iScan HT slide scanner, provides automated digital ...
(Date:8/20/2014)... PHOENIX , Aug. 20, 2014 /PRNewswire-USNewswire/ ... next-generation sequencing and proteomic diagnostics and biomarker driven ... collaboration with TESARO, Inc.  Paradigm will use its ... from clinical trials to better predict which patients ... may lead to more successful clinical trial outcomes ...
Breaking Medicine Technology:Global Market Report of Pralmorelin 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3Paradigm Announces Molecular Profiling Collaboration with TESARO, Inc. 2
... The BiPAP Pro with Bi-Flex bi-level system, ... that the BiPAP Pro takes to change ... Digital Auto-Trak Sensitivity™ which automatically triggers the ... pressures based on the patients breathing rhythm. ...
... Electrophoresis System (PGGE) is designed to ... density lipoproteins (LDL) and high density ... using nondenaturing pore gradient gel electrophoresis. ... short DNA sequencing runs. Temperature control ...
This control is intended for monitoring cell counts in patient cerebrospinal fluid samples, performed manually using a hemocytometer. Spinalscopics is fortified to target levels with purified chemica...
... Suitable for use with Leica ... bilirubinometers (pediatric) and all automated ... including Aeroset, AU Series, Cobas, ... These controls contain purified bilirubin ...
Medicine Products: