Navigation Links
NIH awards $8 million to UT Southwestern to study metabolism, obesity-related inflammation
Date:9/14/2010

DALLAS Sept. 14, 2010 An $8 million grant from the National Institutes of Health will enable UT Southwestern Medical Center to investigate how fat tissue "talks" to the brain and the liver to promote inflammation-related disorders such as diabetes, heart disease and obesity.

The five-year grant takes advantage of expertise across the UT Southwestern campus, including faculty in the Touchstone Center for Diabetes Research, the division of hypothalamic research, and the departments of molecular genetics, internal medicine, and pharmacology.

"We're excited about tackling the complexity of how adipose [fat] tissue, the brain and the liver talk to each other and how this cross talk affects metabolism and inflammation," said Dr. Philipp Scherer, director of the Touchstone Center and principal investigator of the new project. "Getting this grant validates that the UT Southwestern metabolism group is doing state-of-the-art science."

In 2007, the Task Force for Obesity Research at UT Southwestern (TORS) received a $22 million NIH grant to enhance the institution's groundbreaking obesity research.

Dr. Scherer said that while there is clearly synergy with the TORS grant, this new effort is unique because it is specifically focused on phenomena related to inflammation, considered an underlying cause of metabolic disorders in humans.

"We're especially interested in understanding how the brain and the liver influence inflammation and how inflammation influences metabolism within other organs. Those are just a few of the questions our team plans to tackle," Dr. Scherer said.

Large fat cells are a particular area of focus, Dr. Scherer said, because they typically lead to increased cell death and systemic insulin resistance. Under normal circumstances, fat cells continue to grow until the extracellular matrix they've built around themselves is so strong that it's no longer flexible. Once that happens, the cells become
'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. NSF awards stem cell bio-manufacturing research and education program to Georgia Tech
2. Penns Positive Psychology Center awards $2.9 million for research
3. Susan G. Komen awards Case Western Reserve nearly $500,000 to study breast cancer in older women
4. NIH awards Scripps Florida scientists $2.3 Million to develop drug addiction treatments
5. AOSSM presents prestigious research awards at annual meeting
6. Solar Eclipz's Portable Umbrella And Canopy Curtain, Called The ezShade, Wins Coveted Outstanding Product Award From Disney Owned iParenting Media Awards
7. Outstanding high school students receive AGA Foundation 2010 Student Research Fellowship Awards
8. Damon Runyon Cancer Research Foundation awards $3.1M to 8 top young clinical investigators
9. Parkinsons Disease Foundation announces research awards totaling $1.2 million
10. Nominations Wanted for Vascular Disease Foundation President's Awards
11. Dorland Health People Awards Accepting Entries through Friday, June 25, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... (PRWEB) September 21, 2014 Hundreds ... move forward in Pennsylvania’s Philadelphia Court of Common ... documents, the proceeding’s next monthly meeting has been ... number 100300296) , “Our Firm is representing a ... in this litigation. We are pleased with its ...
(Date:9/21/2014)... Dallas, Texas (PRWEB) September 21, 2014 ... Administration (FDA) in 1996, GSK’s Flovent (fluticasone propionate) ... activity. It is used for the maintenance treatment ... is now available in two formulations, Diskus and ... and 2004, respectively. Flovent’s active ingredient, fluticasone propionate, ...
(Date:9/21/2014)... An experienced review website in the global market, Top10BestSEOHosting.com, ... announced that FatCow ( http://www.top10bestseohosting.com/go/FatCow.com/ ), GoDaddy and Bluehost ... has been a boom in websites in recent years, ... in the number of web hosting companies that offer ... VPS (Virtual Private Server) is the method of partitioning ...
(Date:9/21/2014)... 2014 C8 lawsuits move forward in ... the list of 20 possible C8 lawsuits selected ... six, reports Wright & Schulte LLC. Court records show ... 2500 C8 lawsuits filed that represent individuals who purportedly ... a result of being exposed to water contaminated by ...
(Date:9/20/2014)... Diabetes Protocol , a breakthrough new ... thousands of people learn how to naturally manage and ... prescriptions has caught the attention of Shane Michaels, prompting ... of millions of people in the U.S. today who ... and unfortunately, big pharma makes a killing just by ...
Breaking Medicine News(10 mins):Health News:Risperdal Lawsuits Move Forward in Pennsylvania Litigation, As Court Schedules October Meeting, Bernstein Liebhard LLP Reports 2Health News:Risperdal Lawsuits Move Forward in Pennsylvania Litigation, As Court Schedules October Meeting, Bernstein Liebhard LLP Reports 3Health News:Risperdal Lawsuits Move Forward in Pennsylvania Litigation, As Court Schedules October Meeting, Bernstein Liebhard LLP Reports 4Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News:Top10BestSEOHosting.com: FatCow, GoDaddy And Bluehost Are The Best VPS Hosting Suppliers 2Health News:C8 Lawsuit Claims Move Forward as Six Possible Cases for Bellwether Trials Selected in DuPont Water Contamination Lawsuits, Reports Wright & Schulte LLC 2Health News:C8 Lawsuit Claims Move Forward as Six Possible Cases for Bellwether Trials Selected in DuPont Water Contamination Lawsuits, Reports Wright & Schulte LLC 3Health News:C8 Lawsuit Claims Move Forward as Six Possible Cases for Bellwether Trials Selected in DuPont Water Contamination Lawsuits, Reports Wright & Schulte LLC 4Health News:Diabetes Protocol: Review Exposes Kenneth Pullman’s Breakthrough Discovery About Diabetes Management 2
... Recovery for Many Facing Health CrisesCHICAGO, Jan. 15 Does ... challenges have found support and compassion through online communities such ... love is more than a dozen roses or candlelit dinner ... and defying the odds for survival. Just ask Lisa, ...
... information on its revamped website. AccessRx has provided tens of ... 1998. , ... (PRWEB) January 15, ... consumer information on its revamped website. AccessRx has provided tens ...
... Two radon-induced lung cancer survivors will be joined by ... Council Radon Awards Ceremony at the National Press ... the U.S. EPA, the ceremony is part of National ... and winners of the National Radon Poster Contest; but ...
... & Nephew,s Advanced Wound Management division (LSE: SN; NYSE: ... Court in the High Court of Justice of England and ... a temporary injunction prohibiting Smith & Nephew from commercializing foam ... Kingdom. The temporary injunction will remain in place until the ...
... Nationally; Many People May Not Realize They,re InfectedHARRISBURG, Pa., ... in the number of reported cases of gonorrhea and ... testing by men and women, according to the Department ... common bacterial sexually transmitted diseases is below the national ...
... with CorVel Corporation,s (Nasdaq: CRVL ) quarterly earnings release, CorVel will be ... 3rd at 11:30 am Eastern Time. , , Event: ... Dan Starck, President and CEO, ... Date: 11:30 am Eastern Time, Tuesday, ...
Cached Medicine News:Health News:More than Just a Box of Chocolates 2Health News:More than Just a Box of Chocolates 3Health News:AccessRx.com Launches Redesigned Website, Adds Content and Builds Online Community 2Health News:Radiation Victims to Rally In Washington - Demand Congressional Action to Protect Homebuyers; Organization Labels EPA's Radon Program a 'Deadly Failure' 2Health News:Radiation Victims to Rally In Washington - Demand Congressional Action to Protect Homebuyers; Organization Labels EPA's Radon Program a 'Deadly Failure' 3Health News:Smith & Nephew Advanced Wound Management Comments on Temporary Injunction in United Kingdom 2Health News:Smith & Nephew Advanced Wound Management Comments on Temporary Injunction in United Kingdom 3Health News:CorVel Corporation Announces Earnings Release Webcast 2
(Date:9/19/2014)... HILL, N.C. , Sept. 19, 2014 /PRNewswire/ ... role in forging relationships with key opinion leaders ... market and competition. Despite the critical nature of ... created many challenges, including altering the landscape for ... According to research, the oversight responsibility ...
(Date:9/19/2014)... , Sept. 19, 2014 A pharmaceutical executive ... LLC with three issues he wanted the research and ... of external personnel (especially for secondary research) to maximize ... face of increased workload , Automation of market ... management , How to implement and manage those ...
(Date:9/19/2014)... Sept. 19, 2014 "Copay coupons," ... sales of brand drugs among patients with prescription drug ... to a new report  from the Department ... Inspector General (OIG). Federal anti-kickback laws prohibit suppliers ... are subsidized by the federal government. ...
Breaking Medicine Technology:Role of Medical Science Liaisons Shifting in Healthcare Industry 2In Era of Competing Needs, Market Research Groups Under Pressure to Utilize Automation and External Staffing 2PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2
... NxStage Medical, Inc. (Nasdaq: NXTM ), a leading ... its financial results for the third quarter ended September 30, ... of the financial markets. , NxStage will also host a ... 5, 2009 to discuss its third quarter financial results. To ...
... Conn., Oct. 15 AmeriCares has awarded its annual ... the largest health care products and services companies in ... the award today at the Healthcare Distribution Management Association,s ... Power of Partnership Award was created by AmeriCares and ...
Cached Medicine Technology:NxStage(R) to Report Third Quarter 2009 Financial Results 2AmeriCares Honors Cardinal Health with Power of Partnership Award 2AmeriCares Honors Cardinal Health with Power of Partnership Award 3
... Eliminate the need for makeshift, modified nebulizer ... waste time gathering parts when your patient ... to deliver the utmost in Heliox rescue ... is fast becoming the standard of care ...
... Graham-Field has been developing diverse ... 58 years. Our medical-surgical products ... for innovation, quality and customer ... include the Labtron® line of ...
... Entrainment Nebulizers deliver particulate humidity in the ... chronic secretion patients. For your convenience, Thera-Mist® ... supply of sterile water., ,The P30000N, ... of 20-50% with a total flow range ...
... For use with metered dose inhalers., ... aerosolized medication from MDI canisters. Its versatile ... a ventilator circuit, in conjunction with an ... routine, oral inhalation. ACE may also be ...
Medicine Products: