Navigation Links
NIH awards $12.4 million grant to fund Henry Ford Hospital hypertension research

DETROIT A senior staff scientist and his team at Henry Ford Hospital have been awarded a five-year, $12.4 million grant by the National Institutes of Health for their research into the damaging effects of high blood pressure on various organs in the body.

Hypertension is a major public health issue in the United States with an estimated 75 million Americans with the disease, which can also contribute to other major health problems such as heart attack and stroke.

Oscar A. Carretero, M.D., of Henry Ford's Hypertension and Vascular Research Division, is investigating how autacoids, which are small molecules and hormones produced by various cells in the body, regulate kidney function and blood pressure, leading to hypertension and tissue and organ damage.

Although these biological substances and hormones generally affect cells next to or near where they are secreted, they can be transported through the bloodstream. Carretero's research is investigating how, when this happens, they can damage distant tissue and organs. In particular, the various projects are examining the mechanisms by which various autacoids either exacerbate or reduce the pro-hypertensive effects of the hormone angiotensin II.

"I am very proud and grateful to my research team," Carretero said when he learned of the award. "This project took a lot of teamwork and all of the members deserve credit. They worked very hard under a lot of pressure to make this grant possible."

The NIH grant will provide $2,472,318 each year for five years to fund four related projects. Carretero, who is the principal investigator, also heads two of the projects.

Besides Carretero, key among the 18 people involved in the scientific and administrative functions of the grant are Henry Ford's Pamela Harding, Ph.D.; Jeff Garvin, Ph.D.; Xiao-Ping Yang, M.D.; Ed Shesely, Ph.D.; and Ed Peterson, Ph.D.

This research proposal began in 1982 and will now continue through the end of January 2018, continuing NIH funding for 35 years.


Contact: Dwight Angell
Henry Ford Health System

Related medicine news :

1. RWJF awards $1.9 million grant to PatientsLikeMe to create open research platform
2. Kathleen Prasad’s New Book Reiki for Dogs Included in Red Carpet Gift Bags for 85th Academy Awards
3. TraceLink Life Sciences Cloud Named Edison Awards Finalist
4. Empowered Products Releases Its Lists of Best Movies for Lovers in Time for Valentine's Day and Academy Awards Night
5. Clinovations' COO, Kevin Coloton, Chosen for SmartCEO’S 2012 Executive Management Awards
6. Announces Winners of 2013 Dental Excellence Awards
7. eLocal Awards $1000 to The Eliminate Project
8. Johns Hopkins neuroscientists win National Academy of Science Awards
9. IRSF awards $1.5 million for novel basic and translational research programs
10. Biophysical Society announces winners of 2013 Minority Affairs Committee travel awards
11. Author, Speaker, Healer, Nina Brown Recognized by 2012 USA Best Book Awards
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... The ... of USA Today in Atlanta, Dallas, New York, Minneapolis, South Florida, with a ... component is distributed nationally, through a vast social media strategy and across a ...
(Date:11/27/2015)... ... November 27, 2015 , ... Consistent with ... the 2016 Building Better Radiology Marketing Programs meeting will showcase some ... March 6, 2016, at Caesars Palace in Las Vegas with a pre-conference session ...
(Date:11/27/2015)... ... 2015 , ... The moment you stop improving is the ... the needs of advisers and clients but going above and beyond to find ... service. However, there's always room for improvement, which is why the entire Consulting ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... most successful and prominent nonprofit healthcare organizations in the country. They have overseen ... various organizations, and helped advance the healthcare industry as a whole through their ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... contact center software Q-Suite, announces the incorporation of Asterisk 11 LTS (Long Term ... fully supported Asterisk 11 LTS brings Q-Suite 5.10 up-to-date with a version of ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... YORK , November 27, 2015 ... system is set to go online. The potential to ... processes is vast and far from fully exploited as ... to patient health records, either via mobile tablet or ... ) --> ) --> ...
(Date:11/26/2015)... , November 27, 2015 ... --> --> ... emergency response system (PERS) market ... for 5 years with APAC ... expected to see a high ...
(Date:11/26/2015)... 2015 --> --> ... to find optimal contrast weighting of MRI for patients ... signed a research agreement with SyntheticMR in order to use ... it is possible to generate multiple contrast images from a ... has left, thus making it possible to both fine tune ...
Breaking Medicine Technology: