Navigation Links
NIH awards $10M to Einstein for diabetes research
Date:5/25/2010

May 25, 2010 (BRONX, NY) The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) has awarded Albert Einstein College of Medicine of Yeshiva University a five-year, $9.5 million grant for the continuation of its Diabetes Research and Training Center (DRTC). The DRTC was also awarded a $632,000 supplemental grant for equipment and additional pilot and feasibility studies through the American Recovery and Reinvestment Act (ARRA), bringing total NIH support to $10,177,000.

"These grants come at a critical time," said Jeffrey Pessin, Ph.D., principal investigator and director of Einstein's DRTC who holds the Judy R. and Alfred A. Rosenberg Professorial Chair in Diabetes Research and is also professor of medicine and of molecular pharmacology at Einstein.

"Diabetes is already a major threat to public health and its prevalence is quickly rising not only here in the Bronx, but also nationally and internationally," continued Dr. Pessin. "With this new funding, we will be able to continue our important work, which is to support research and training related to diabetes and its complications, and to translate new discoveries into better care for people with diabetes."

Einstein's DRTC was among the first group of diabetes centers established by the NIH in the 1970s. Today, it is the only comprehensive center in New York and one of only seven DRTCs nationwide.

The DRTC is part of a larger diabetes program at Einstein, the Diabetes Research Center (DRC), which supports basic, clinical, behavioral and translational research. The DRC also includes the Global Diabetes Initiative, which conducts research and education to combat the world's burgeoning diabetes epidemic.

"Einstein investigators have made major contributions to diabetes research since the DRTC's inception over three decades ago, a tribute to Norman Fleischer, M.D., the first DRTC director," said Allen M. Spiegel, M.D., the Marilyn and Stanley M. Katz Dean. "This award enables the DRTC to continue its vital role in improving prospects for prevention and treatment of types 1 and 2 diabetes under the new leadership of Dr. Pessin."

Dr. Spiegel added, "The opening of the Michael F. Price Center for Genetic and Translational Medicine/Harold and Muriel Block Research Pavilion has enabled Einstein to augment its strength in diabetes research with the recruitment of Dr. Pessin and several new outstanding diabetes investigators."

The Einstein DRTC supports a variety of basic research projects. Of particular note are studies involving the central nervous system's crucial role in diabetes a field pioneered by Einstein researchers about a decade ago. It's now known that the brain helps in controlling energy expenditure, metabolism, and insulin sensitivity.

Einstein researchers are also recognized for studies of the epigenetics of diabetes and obesity focusing on how environmental factors, such as chemical exposures, influence gene expression and lead to disease. In addition, the DRTC at Einstein has a strong research effort into diabetic complications, with a particular focus on kidney disease.

"The ultimate goal of these studies is to develop new therapies for the prevention or treatment of diabetes," said Dr. Pessin. "For example, we recently mapped a signaling pathway that controls energy expenditure in mice. By blocking this pathway, we can increase energy expenditure and cause weight loss in these animals. We're now trying to develop drugs that can interfere with this pathway in humans. If we're successful, we'll take our findings to clinical trials."

To support its various research efforts, Einstein's DRTC has established several research cores, which give individual investigators access to technologies, equipment, and expertise that they could not assemble on their own. There are now six research cores: animal physiology, hormone assay, analytical imaging, flow cytometry, epigenomics, and stable isotope & metabolomics. The metabolomics core provides novel approaches to analyze metabolism in individual cells, tissues, or whole organisms, including humans.

Einstein's DRTC is also noteworthy for its prevention and control component, through which interventions are developed to promote healthy lifestyle changes in adults and children as well as adherence to therapies for preventing or treating diabetes. In addition, members of this component conduct research aimed at reducing health disparities, working closely with the local community and other underserved minority populations. The Bronx is the poorest urban county in the U.S. and has a high prevalence of diabetes and obesity.


'/>"/>

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Related medicine news :

1. Senior Healthcare Executives to Lead Hospital Charitable Service Awards
2. USA Hockey Takes Gold at Brain Fitness Innovation Awards; Allstate & Nationwide Mutual Insurance Runners-up
3. Tahitian Noni International Named As Finalist In 2010 American Business Awards
4. FightSMA Awards $250,000 Grant to Gene Researcher at The Ohio State University
5. American Cancer Society awards 152 new research and training grants
6. IADR and GSK Consumer Healthcare announce winners of 2010 Innovation in Oral Care Awards
7. RAPS Seeks Nominations for Regulatory Awards, RAPS Fellows
8. iCMG Architecture Awards for Truly Outstanding Enterprise and IT Excellence
9. Mowers Recognized At 2010 Utah Genius Awards
10. NIH awards $2.7-million grant to Kent State to study cognitive impairment in heart failure patients
11. NIH awards $10 million to Rush University Medical Center to address health disparities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their ... Eyeglasses . , Millions of individuals in the United States and Canada wear eyeglasses. ... way to both correct vision and make a fashion statement. Even celebrities use glasses ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can ... Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey ... cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... , June 23, 2016  In a startling report released ... failing their residents by lacking a comprehensive, proven plan to eliminate ... a definitive ranking of how states are tackling the worst drug ... only four states – Kentucky , ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
Breaking Medicine Technology: