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NIH Recovery Act awards enable crucial health research technologies
Date:10/21/2010

the technology even further and allow them to see more details of the human brain, as well as the human torso and extremities, thereby improving disease detection and treatment monitoring.

  • Using nearly $8 million, investigators at the University of Maryland, Baltimore have purchased a powerful 950 megahertz nuclear magnetic resonance spectrometer, to study human tissues and cells in atomic detail. Researchers from across the mid-Atlantic region will use this imaging device one of just two in the country to identify new ways to treat cancer, HIV/AIDS and heart disease, and to design more effective drugs. These spectrometers apply strong magnetic fields to biological samples to extract information about the identity and locations of atoms within proteins, fats and other molecules. By analyzing cells and tissues in such detail, researchers can learn about disease processes and possible treatments.

  • To examine cell division in detail, researchers at the University of Washington in Seattle will use a nearly $215,000 award to develop a multicolor total internal reflection fluorescence microscope. This instrument overcomes a major obstacle of conventional fluorescence microscopy that leads to blurry images when fluorescent target molecules inside a cell are too close to one another. Using this microscope, researchers at the University of Washington plan to obtain detailed views of the cellular apparatus components responsible for pulling apart chromosomes as cells divide. The insights gained promise to revolutionize the design of cancer drugs that target these components.

    "Innovative research requires access to the latest technologies," said NCRR Director Barbara Alving, M.D. "These high-performance tools will ensure that NIH-funded investigators remain at the forefront of modern biomedical research."

    NCRR's instrumentation grants fall under two categories. The Shared Instrumentation Grant (SIG) program provides funding
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  • Contact: Bobbi Gardner
    bobbi.gardner@nih.gov
    310-443-9919
    NIH/National Center for Research Resources
    Source:Eurekalert

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