Navigation Links
NIH Grant to support Mount Sinai Research Program to Create Biological Network Model of Alzheimer’s Disease in partnership with New York Stem Cell Foundation
Date:9/18/2013

lines from a large number of patients in a massively parallel process. “Existing approaches have failed to identify new Alzheimer’s therapeutics and I believe that through this multifaceted approach we will collaborate to identify and validate new drug targets for Alzheimer’s patients,” said Dr. Noggle.

Sam Gandy, MD, PhD, Director of the Center for Cognitive Health at Mount Sinai, and a principal investigator in the study, said, “This research is of paramount importance. Currently, no effective disease-modifying or preventive drugs exist for common, late onset Alzheimer’s Disease. Despite decades of intensive conventional research, the causal chain of mechanisms behind sporadic Alzheimer’s Disease has remained elusive. This multi-scale, computational strategy, combined with target validation in mouse brain, in fly brain, and in stem cell models, is already providing clues to unanticipated pathways and new drug discovery opportunities.”

The NIH grant (NIA grant AG 046170-01) was developed under a recent initiative specifically aimed at understanding the complexity of Alzheimer’s disease. This approach assumes that Alzheimer’s might best be explained and treated by focusing on genes that serve as “hubs” that interconnect a group of genes. These hubs are important because when they malfunction and cause Alzheimer’s, they cause predictable malfunctions of the entire group of connected genes. This approach leverages big data and high-end analytical approaches to develop predictive network models of disease. As a key source of data, the Mount Sinai investigators will study gene expression in brains from the Mount Sinai Alzheimer’s Disease Research Center Brain Bank that specializes in identifying the very earliest stages of Alzheimer’s. This brain bank was established over 35 years ago and is considered to be one of the best such resources in the world.

About The Mount Sinai Medical Center
The Mount Sinai Medical Center encompas
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Federal Grant of $275,000 Funds Study of Young Adult Attitudes Toward Flavored Tobacco
2. Federal grant of $275,000 funds study of young adult attitudes toward flavored tobacco
3. Life Sciences Discovery Fund announces $3.7m in research and development grants
4. Tri-County Electric People Fund Awards Grant To Eagle Village
5. Mount Sinai Grants Exclusive License to Plexcera Therapeutics to Develop Treatments for Farber Disease and Cystic Fibrosis
6. New NIH grants to investigate disease-related variations in genetic makeup
7. Rice University wins neuroengineering grant
8. Mount Sinai Receives NIH Grant to Increase the Engagement of African Americans in Colorectal Cancer Screening
9. Mount Sinai receives NIH grant to increase colorectal cancer screenings in African Americans
10. NIH grants Brown University $11M for brain research
11. Parascript Granted FDA Approval for Mammography Computer-Aided Detection System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... July 24, 2014 (HealthDay News) -- Drinking caffeine may ... roughly two-thirds of women as they go through menopause, ... preliminary, our study suggests that limiting caffeine intake may ... hot flashes and night sweats," said researcher Dr. Stephanie ... Mayo Clinic in Rochester, Minn. But caffeine -- ...
(Date:7/24/2014)... Hospital and the University of Tennessee Health Science Center ... drug shown to safely reduce the viral load and ... respiratory syncytial virus (RSV). RSV is the most common ... in the United States and worldwide. , The ... John DeVincenzo, MD. DeVincenzo,s Le Bonheur lab has been ...
(Date:7/24/2014)... As the age of marriage and childbirth ... a way to ensure future family building options by ... reproductive age. Vitrification technology, a fast freeze method for ... that allows a woman to have multiple eggs retrieved ... are then stored for future use. When circumstances allow, ...
(Date:7/24/2014)... 24, 2014 In a recent report by ... officially put an end to criminal penalties associated with possession ... era for marijuana reform in Washington DC, giving it one ... law replaces criminal penalties for possession of one ounce of ... the possession of more than an ounce of marijuana remain ...
(Date:7/24/2014)... PROVIDENCE, R.I. Lynn E. Taylor, M.D., director ... states in the July, 2014 Rhode Island ... C" that eliminating hepatitis c virus infection (hep ... benefits, enhance capacity to address other health challenges, ... HCV in the United States, Taylor says, include ...
Breaking Medicine News(10 mins):Health News:Is Coffee Aggravating Your Hot Flashes? 2Health News:RSV research breakthrough to help infected children 2Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 2Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 3Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 4Health News:Washington D.C. Decriminalizes Marijuana 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 3Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 4
... Nov. 6 Those biopharmaceutical companies that are ... their business models will be best positioned to ... according to a white paper published today by ... equity firm, and Health Advances, a leading healthcare ...
... 6 Bulletproof Blog , the ... with former Speaker of the U.S. House of Representatives ... to effect America,s business landscape. , In the interview, ... impacting the crossroads of business and government, including healthcare ...
... Nov. 6 Allied World Assurance,Company Holdings, Ltd ... World U.S.,Nicole Baummer, Assistant Vice President for Private/Not-for-Profit ... Lines,Claims, will be speaking at this year,s Professional ... in Chicago, Illinois,November 11-13, 2009. , ...
... 6 We Work for Health, an alliance of ... released the results of a first-of-its-kind economic impact study ... passed many of the traditional resource-based industries on which ... same range of importance as some of the new, ...
... Nov. 6 The current health care debate in the ... choices and life expectancy have been suggested but seldom clearly ... year on health care for every 80 year old, while ... octogenarians have a 20 percent less chance of dying than ...
... food choices in study , FRIDAY, Nov. 6 (HealthDay News) ... choices, researchers say. , The new study included 542 male ... irregular shifts. The average age of the participants was 49, ... sleep medicine division at Harvard Medical School found that adequate ...
Cached Medicine News:Health News:Surviving Healthcare Reform: How Biopharma Companies Can Come Out on Top 2Health News:Former House Speaker Newt Gingrich Shares Insights on Healthcare Reform and the Federal Pay Czar with BulletproofBlog.com 2Health News:Allied World's Nicole Baummer and Marjorie Thompson to Speak at PLUS International Conference 2Health News:Allied World's Nicole Baummer and Marjorie Thompson to Speak at PLUS International Conference 3Health News:New Study: Life Science Jobs Total 77,000 in Washington State 2Health News:New Study: Life Science Jobs Total 77,000 in Washington State 3Health News:Carnegie Mellon Researcher Links Health Care Debate to Risk of Dying in the U.S. and Europe 2Health News:Carnegie Mellon Researcher Links Health Care Debate to Risk of Dying in the U.S. and Europe 3Health News:Carnegie Mellon Researcher Links Health Care Debate to Risk of Dying in the U.S. and Europe 4
(Date:7/24/2014)... , July 24, 2014 LSI Medience ... an Agreement with Kineticos, a Raleigh-Durham, ... Kineticos will support LSI Medience in identifying opportunities ... to demonstrate utility in clinical trials. ... utility in diagnosis of sepsis, prognosis of septic ...
(Date:7/24/2014)... , July 24, 2014  Lazarus Effect, ... of novel interventional devices to facilitate removal of ... Patent and Trademark Office has issued a new ... behind the company,s Lazarus Cover TM and ... Lazarus ReCover is a single-component stent-retriever (stentriever) with ...
(Date:7/24/2014)... July 24, 2014 /PRNewswire-iReach/ -- "North America Orthopedic Braces ... data on the North America Orthopedic Braces and Supports ... dollars, and volume (in units) and average price data ... Knee Braces and Supports , Ankle Braces and ... Upper Extremities Braces and Supports. ...
Breaking Medicine Technology:LSI Medience Corporation and Kineticos Sign Agreement Related to the Presepsin Biomarker in Sepsis Management and Treatment 2Lazarus Effect Receives Notice of Allowance for New US Patent Covering Core Protection Technology 2North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 2North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 3North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 4North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 5
... , POTOMAC FALLS, Va., Nov. 9 TessArae® ... announces the launch of new integrated product solutions ... human hereditary diseases. The combination of TessArae,s ... basecalling algorithms and analysis software enables screening for ...
... /PRNewswire/ -- On Sept. 11, 2001, thousands of ... save as many lives as possible in New York City. ... responders. Now he is fighting to save his own life. ... cancer in 2006. He has undergone surgery and extensive chemotherapy ...
Cached Medicine Technology:TessArae Delivers Lower Cost Option to Genetic Testing Market 2The SCOOTER Store Surprises 9/11 First Responder & Merrick Firefighter With Power Chair 2The SCOOTER Store Surprises 9/11 First Responder & Merrick Firefighter With Power Chair 3
... Basic ergonomic chairs with concave seats ... • Select options like seats, backrests, ... BTC/1Q chairs are recommended for the ... room, static control, health care and ...
... concave seats and standard-sized backrests with ... seats, backrests, armrests, and casters and ... for the following environments: industry, education, ... care and office. • With cast ...
... ergonomic chairs with concave seats and ... Select options like seats, backrests, armrests, ... chairs are recommended for the following ... static control, health care and office. ...
... chairs with concave seats and standard-sized ... options like seats, backrests, armrests, and ... are recommended for the following environments: ... control, health care and office. • ...
Medicine Products: