Navigation Links
NIH Grant to support Mount Sinai Research Program to Create Biological Network Model of Alzheimer’s Disease in partnership with New York Stem Cell Foundation
Date:9/18/2013

lines from a large number of patients in a massively parallel process. “Existing approaches have failed to identify new Alzheimer’s therapeutics and I believe that through this multifaceted approach we will collaborate to identify and validate new drug targets for Alzheimer’s patients,” said Dr. Noggle.

Sam Gandy, MD, PhD, Director of the Center for Cognitive Health at Mount Sinai, and a principal investigator in the study, said, “This research is of paramount importance. Currently, no effective disease-modifying or preventive drugs exist for common, late onset Alzheimer’s Disease. Despite decades of intensive conventional research, the causal chain of mechanisms behind sporadic Alzheimer’s Disease has remained elusive. This multi-scale, computational strategy, combined with target validation in mouse brain, in fly brain, and in stem cell models, is already providing clues to unanticipated pathways and new drug discovery opportunities.”

The NIH grant (NIA grant AG 046170-01) was developed under a recent initiative specifically aimed at understanding the complexity of Alzheimer’s disease. This approach assumes that Alzheimer’s might best be explained and treated by focusing on genes that serve as “hubs” that interconnect a group of genes. These hubs are important because when they malfunction and cause Alzheimer’s, they cause predictable malfunctions of the entire group of connected genes. This approach leverages big data and high-end analytical approaches to develop predictive network models of disease. As a key source of data, the Mount Sinai investigators will study gene expression in brains from the Mount Sinai Alzheimer’s Disease Research Center Brain Bank that specializes in identifying the very earliest stages of Alzheimer’s. This brain bank was established over 35 years ago and is considered to be one of the best such resources in the world.

About The Mount Sinai Medical Center
The Mount Sinai Medical Center encompas
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Federal Grant of $275,000 Funds Study of Young Adult Attitudes Toward Flavored Tobacco
2. Federal grant of $275,000 funds study of young adult attitudes toward flavored tobacco
3. Life Sciences Discovery Fund announces $3.7m in research and development grants
4. Tri-County Electric People Fund Awards Grant To Eagle Village
5. Mount Sinai Grants Exclusive License to Plexcera Therapeutics to Develop Treatments for Farber Disease and Cystic Fibrosis
6. New NIH grants to investigate disease-related variations in genetic makeup
7. Rice University wins neuroengineering grant
8. Mount Sinai Receives NIH Grant to Increase the Engagement of African Americans in Colorectal Cancer Screening
9. Mount Sinai receives NIH grant to increase colorectal cancer screenings in African Americans
10. NIH grants Brown University $11M for brain research
11. Parascript Granted FDA Approval for Mammography Computer-Aided Detection System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has ... View website of AngelWeddingDress.com to find more ... dresses online for a bridal party. AngelWeddingDress offers a ... them. Its maternity wedding dresses are specially designed for ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining the ... . , Auto insurance quotes help many drivers find ... necessary to call an agent or visit an agency for ... single website: http://autocarinsurancebest.com/ . , Every business who relies ...
(Date:1/22/2015)... 2015 Yesterday, Senator Holly Mitchell ... Kristin Olsen (R-Modesto) were honored by the California ... biotechnology, biomedical science, medical device and pharmaceutical innovation ... the “2014 Life Sciences Champion” award from CHI ...
(Date:1/22/2015)... January 22, 2015 EBSCO Information Services ... are expanding their relationship in an effort to further promote ... world. While EBSCO has long made AMA journals available via ... agent for The JAMA Network. , Long known ...
(Date:1/22/2015)... Step into a macabre world where ... of Virginia. Wicked Plants, the Museum’s latest featured exhibition, ... poisonous, carnivorous and diabolical plants inside of a dilapidated, ... the biochemical, physical and neurological processes between botanicals and ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... patients with coronary artery disease were almost three times ... interventional treatment to arterial plaque than their White European ... IJCP, the International Journal of Clinical Practice . ... emergency and require urgent treatment. Researchers carried out ...
... in sexual activity, the more likely they are to ... to new research presented in Boston at The Gerontological ... This finding is based on the 2004� General Social ... representative sample of non-institutionalized English and Spanish-speaking person 18 ...
... FRIDAY, Nov. 18 (HealthDay News) -- New research suggests that ... communicating via email or instant messages rather than when they ... What,s new is that we lie even more online," said ... at the University of Massachusetts-Amherst. In the study, the ...
... - IBM,s Watson computing system broke new ground earlier this ... Jeopardy! game show. Now, The Scripps Research Institute is hoping ... health with part of the prize money from that tournament: ... the public,s help. To that end, Scripps Research ...
... at the University of California, San Diego School of Medicine ... colleagues in Boston and South Korea, say they have identified ... of glioblastoma (GBM), the most common type of malignant brain ... online edition of the journal Cancer Research . ...
... 2011 - The Canadian Diabetes Association is pleased to ... Elsevier to publish the Canadian Journal of Diabetes ... CJD is Canada,s only diabetes-oriented, peer-reviewed, interdisciplinary ... the sharing and enhancement of knowledge to advance the ...
Cached Medicine News:Health News:South Asian patients require 3 times as much repeat angioplasty as white Europeans 2Health News:South Asian patients require 3 times as much repeat angioplasty as white Europeans 3Health News:Study finds sex a significant predictor of happiness among married seniors 2Health News:People May Lie More Often in Emails, Instant Messages 2Health News:Jeopardy! winnings spur IBM and Scripps Research Institute collaboration to fight against malaria 2Health News:Jeopardy! winnings spur IBM and Scripps Research Institute collaboration to fight against malaria 3Health News:Old drugs find new target for treating brain tumor 2Health News:Old drugs find new target for treating brain tumor 3
(Date:1/23/2015)... , Jan. 23, 2015  MedScope ( www.medscope.org ), the ... for a 2015 Connected World magazine Connected ... System (mPERS), that can be used anywhere, anytime. The ... In nominating MedScope, Landon Garner ...
(Date:1/23/2015)... Rose, baseball,s all-time hits leader, is the new spokesperson for ... Pharma has announced. "Pete,s a Hall of Famer ... on board with Myoflex," said Ducere Pharma Chief Executive Officer ... is known across all generations. The passion and intensity that ...
(Date:1/23/2015)... , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. (OTCQB: LIXT), ... I trial of Lixte,s lead compound, LB‑100, is being conducted, ... John S. Kovach , M.D., the founder and President ... be completed at a single site. Accrual of patients, however, ...
Breaking Medicine Technology:MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2Pete Rose bets on Myoflex to relieve aches and pains 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3
... Denali Concrete Management Inc. (OTCBB: DCMG) announced today ... acquisition of Denali by Can-Fite BioPharma Ltd. (TASE: CFBI) ... outstanding shares of EyeFite Ltd., a private company incorporated ... exclusive license over CF101 for ophthalmic indications. Concurrently, Denali ...
... 22, 2011 Par Pharmaceutical Companies, Inc. (NYSE: ... approved the promotions of Thomas J. Haughey to the role ... Chief Operating Officer of the Company and its subsidiaries, effective ... LePore who will retain his title of Chairman of the ...
Cached Medicine Technology:Denali Concrete Management Inc. Announces its Acquisition of CF101 for Ophthalmic Indications and the Completion of Above $6 Million Private Placement at $1.144 Per Share 2Denali Concrete Management Inc. Announces its Acquisition of CF101 for Ophthalmic Indications and the Completion of Above $6 Million Private Placement at $1.144 Per Share 3Par Pharmaceutical Companies Promotes Thomas J. Haughey to President and Paul V. Campanelli to Chief Operating Officer 2
Used for dilation of a tract to the kidney for removal of stones. Supplied sterile in peel-open packages. Intended for one-time use....
... supplied on Smart Cards. Insert the card and ... and turns itself off after the programmed time. ... duration of treatments. Simply provide your patient with ... their progress on the next visit.,The initial set ...
... painfree therapy stimulates the spincter and ... contractions and relaxation. By use of ... surgical operations (bladder liftings) may be ... can improve unsatisfying results. DETRUSAM intravesical ...
... ELPHA 4 Conti is a battery operated ... treatment of conditions described below. ELPHA 4 Conti ... In STRESS- and faecal incontinence ELPHA 4 Conti ... that the user can feel which muscles need ...
Medicine Products: