Navigation Links
NICE SUGAR: Intensive insulin therapy risks
Date:3/24/2009

OTTAWA, ONTARIO, CANADA Intensive insulin therapy significantly increases the risk of hypoglycemia in critically ill patients, found a new study in CMAJ (http://www.cmaj.ca/press/cmaj.090206.pdf).

Intensive insulin therapy is used in many intensive care units around the world as a means to tightly regulate blood sugar. Although labour intensive, it has been recommended as a standard of care for critically ill patients by many organizations including the American Diabetes Association and the American Association of Clinical Endocrinologists.

A randomized trial in 2001 reported that intensive insulin therapy significantly reduced hospital mortality, although subsequent trials have reported inconsistent effects on mortality and higher rates of severe hypoglycemia.

The CMAJ study includes data from 26 trials, including the NICE-SUGAR Study on intensive insulin therapy, an international, multicentre randomized trial that is the largest intensive insulin therapy trial to date. The NICE-SUGAR study is published online in the New England Journal of Medicine March 24, 2009 and March 26 for the print edition.

"By including the largest trial on intensive insulin therapy published to date, we provide the most current and precise estimate of the effect of intensive insulin therapy on vital status and hypoglycemia in the ICU setting," write Dr. Donald Griesdale, anesthesiologist and critical care physician at Vancouver General Hospital and clinical instructor at the University of British Columbia, and coauthors.

The CMAJ study looked at 26 trials involving 13 567 patients. There was a 6-fold increased risk of hypoglycemia compared to the control treatment.

The study was conducted by researchers from the University of British Columbia and Vancouver General Hospital, Vancouver, BC; Harvard School of Public Health, Brigham and Women's Hospital, Beth Israel De
'/>"/>

Contact: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-731-8610 x2224
Canadian Medical Association Journal
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dallas To Host Intensive Norvax University Insurance Agent Sales Training and Web Marketing Conference on March 26
2. New Anxiety and Mood Disorders Intensive Treatment Program in Downtown Chicago
3. Intensive Resource Group (IRG) Helps Hospitals Address Financial and Operational Crisis
4. Intensive Insulin Therapy Reduces Mortality in Sick Kids
5. Intensive support programs can help hospitalized smokers stay smoke-free
6. Integrated Medical Systems Receives FDA Clearance for Worlds First Suitcase Intensive Care Unit
7. New Intensive Care Unit at Gilbert Hospital Sees First Patient
8. WellPoint Partners With CareNex Health Services to Expand Its Neonatal Intensive Care Services Program
9. Newborns in Intensive Care Often Exposed to Pain
10. Less Intensive Treatment Given Diabetic Women With Heart Disease
11. Cystic Fibrosis Foundation Hosts Quality Improvement Summit - Caregivers from 15 States and Canada Gather in Hartford for Intensive Learning
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... has been awarded one of 30 grants from the ... Academic Participating Site in its new National Clinical ... select groups of investigators charged with distributing resources in ... NCTN grant system reflects recommendations from a 2010 ... achieve four goals:, Faster design, launch, and ...
(Date:4/24/2014)... the influenza pH1N1 virus caused the first flu pandemic ... May 2009 and killed more than 50 people in ... mainly during flu epidemics (winter/spring seasons). , Infections ... complicated illnesses. World Health Organization has recommended Tamiflu for ... disadvantage of this drug is that it targets viral ...
(Date:4/23/2014)... Using frozen stool from healthy, unrelated donors was ... relapsing diarrhea caused by Clostridium difficile , ... Clinical Infectious Diseases and available online. ... equally effective whether given via a colonoscope or ... may make this promising treatment more readily available ...
(Date:4/23/2014)... Spokane have developed a new way to detect ... the wheel. , Their recently patented technology is ... in drowsy driversand offers an affordable and more ... detection systems. , Van Dongen"Video-based systems that use ... out of its lane are cumbersome and expensive," ...
(Date:4/23/2014)... April 23, 2014 The American Society for Radiation ... Role of Postoperative Radiation Therapy for Endometrial Cancer: ... of adjuvant radiation therapy in the treatment of ... in the May-June 2014 issue of Practical ... journal of ASTRO. The full-length guideline is available ...
Breaking Medicine News(10 mins):Health News:Dartmouth awarded lead role in NCI clinical trials network 2Health News:Dartmouth awarded lead role in NCI clinical trials network 3Health News:Pilot study suggests ways to widen access to fecal transplants for C. diff infections 2Health News:WSU innovation improves drowsy driver detection 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 2Health News:ASTRO issues guideline on the role of postoperative radiation therapy for endometrial cancer 3
... , , , , ... Inc. announced today that the Dakim(R) BrainFitness(TM) System has now been adopted ... their defenses against dementia and memory loss. Dakim has added 136 new ... brain training system provider in the senior care market. , ...
... University of the Negev (BGU) researchers, in a collaboration ... identified a signaling pathway that is operational in intra-abdominal ... to obesity-related morbidity. The paper was just ... Clinical Endocrinology and Metabolism ( J. Clin. Endocrinol. ...
... ... Consumer Use , ... (Vocus) July 14, 2009 -- HemCon Medical Technologies , Inc. today announced that its ... and home settings for anterior nasal bleeding. The nasal care products will be available ...
... , DETROIT, July 14 Major depression ... billion. It is currently the leading cause of disability in the ... Approximately 4% of adolescents develop major depression each year and by 2020, ... , , All of this need ...
... any damage is to stop them in their tracks before ... Yiping Han, associate professor at the Case Western Reserve University ... roadblocks for a common bacterium that,s harmless in a mother,s ... child. She has received a five-year, $1.85 million grant ...
... (API), who are in the sexual minority, face psychological ... and ancestral cultures that significantly impact the development of ... teens and young adults identified as gay, lesbian, bisexual, ... their western or Caucasian peers, which can lead to ...
Cached Medicine News:Health News:Dakim BrainFitness Now Used in 286 Senior Living Communities, Adding 136 Sites in 12 Months for Dementia-Fighting System 2Health News:Dakim BrainFitness Now Used in 286 Senior Living Communities, Adding 136 Sites in 12 Months for Dementia-Fighting System 3Health News:Ben-Gurion U. researchers identify how stressed fat tissue malfunctions 2Health News:New HemCon/Seal-On Nasal Plugs Control Nosebleeds Quickly, Effectively and Comfortably 2Health News:New HemCon/Seal-On Nasal Plugs Control Nosebleeds Quickly, Effectively and Comfortably 3Health News:Healing Depression The Mind-Body Way Aims to 'Depression-Proof' Your Life 2Health News:Stopping harmful oral bacteria in its path is goal for Case Western Reserve researcher 2Health News:Understanding the process of homosexual identity formation among Asian and Pacific Islander youth 2Health News:Understanding the process of homosexual identity formation among Asian and Pacific Islander youth 3
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) announces ... condition to the announced tender offer for all of the outstanding ... result of the waiver, the transaction is no longer conditional on ... January 24, 2014 following the currently scheduled expiration time, subject to ...
(Date:1/15/2014)... Tegra Medical is very pleased to announce the appointment ... Chief Executive Officer.  Mark was promoted from his current role ... company,s four facilities in Massachusetts , ... Tegra Medical in 2012 with 20+ years of broad-based operations, ...
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... & Forecast – Worldwide Analysis ... Pump Market Analysis ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17
... October 12, 2011 Aircraft Medical ("Aircraft"), ... has signed an exclusive agreement with Covidien (NYSE: ... products with 2010 revenue of $10.4 billion, and 41,000 ... agreement, Covidien will market and distribute Aircraft,s proprietary McGRATH ...
... October 12, 2011 OctreoPharm Sciences ... today that the European Medicines Agency has granted ... for the diagnosis of gastro-entero-pancreatic neuroendocrine tumours. ... to ten year market exclusivity in Europe following ...
Cached Medicine Technology:Aircraft Medical Signs Multinational Distribution Agreement with Covidien for McGRATH® MAC Video Laryngoscope 2OctreoPharm Sciences Receives Orphan Drug Designation for SOMscan® for the Diagnosis of Neuroendocrine Tumours 2
... Triage BNP Test is the first ... measuring B-type natriuretic peptide (BNP) ,Cardiac ... in response to ventricular volume expansion ... of ventricular systolic and diastolic dysfunction. ...
... Building on over 20 years of ... platforms for the Life Sciences, the ... flexibility and possibilities for expansion according ... new easy-to-use software, Freedom EVOware, each ...
... (OSS) from Biomet Inc. offers the ... specifically for orthopaedic surgeons and oncologists ... their patients: significant bone loss, ligamentous ... arthroplasties, and multiple hip revision arthroplasties. ...
The generously sized STERILE VIEW Monk Hood from DePuy provides splash protection in the chin and neck areas from body fluids and liquids. Shoulder cut outs and ties ensure a comfortable fit. This pr...
Medicine Products: