Navigation Links
NIAID media availability: Still searching for predictors of asthma attacks
Date:8/10/2009

A new study of persistent asthma in inner-city adolescents and young adults finds that an extensive set of clinical tests cannot successfully predict the future risk of asthma attacks in participants who both receive care based on current guidelines and adhere to treatment recommendations. This finding differs from previous reports suggesting that certain clinical findings and laboratory tests could help predict future asthma attacks. These earlier conclusions, however, were based on observations of patients with poorly controlled asthma who had not received care based on current guidelines.

The study was conducted by the Inner City Asthma Consortium (ICAC), a nationwide network of clinical researchers supported by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. ICAC member Rebecca Gruchalla, M.D., Ph.D., from the University of Texas Southwestern Medical Center in Dallas, led the study. Additional support for the research was provided by the NIH National Center for Research Resources.

The 46-week study included 546 adolescents and young adults (ages 12 to 20 years old) in 10 cities across the United States. At the start of the study, ICAC investigators gathered baseline data by conducting standard tests to assess asthma symptoms. An additional battery of tests evaluated lung inflammation, lung function and allergic status. The participants were then seen every 6 to 8 weeks at their respective ICAC centers, where they were they were treated for asthma based on NIH guidelines developed by the National Asthma Education and Prevention Program. During the study, the participants carefully adhered to their treatment regimens.

After the study was completed, the investigators analyzed the baseline measurements to determine if any of these assessments, alone or in combination, could predict future asthma symptoms or asthma attacks. The investigators observed no significant clinical correlations between these common laboratory test measurements and asthma exacerbations among the study participants.

This large, longitudinal study provides the most comprehensive analysis to date of a number of factors previously thought to be useful in predicting future asthma attacks. Based on a population of patients who followed their treatment and had well-controlled asthma, the results indicate clearly that there are no known common biological markers that can predict the course of the disease in such individuals. Further studies will be needed to identify possible predictive markers.


'/>"/>

Contact: Julie Wu
wujuli@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

Related medicine news :

1. NIAID funds $51M contract to create comprehensive model of immune responses
2. NIAID strengthens and expands Vaccine and Treatment Evaluation Units
3. NIAID scientists identify new cellular receptor for HIV
4. NIAID to convene HIV Vaccine Summit
5. NIAID describes research priorities to fight drug-resistant tuberculosis
6. NIAID to advance B-cell approach to HIV vaccines
7. NIAID creates HIV vaccine discovery branch
8. NIAID awards contracts to search for protein markers of disease
9. NIAID media availability: Seizures following parasitic infection associated with brain swelling
10. NIAID honors AIDS activist Martin Delaney
11. NIAID and Chinese officials sign agreement to foster TB research in Chinas Henan province
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... WILMINGTON, Del. (PRWEB) , ... October 12, 2017 ... ... technology and advisory services for healthcare compliance program management, will showcase a range ... and National Association for Assisted Living (NCAL) Convention and Expo to be held ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... products to meet the demand of today’s consumer and regulatory authorities worldwide. From ... probiotic experts and tested to meet the highest standard. , These products ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, ... post-acute health care, have expanded their existing home health joint venture through an ... has been operating a joint venture home health company with Asante, delivering clinically ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... -- HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy ... team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D ...
(Date:9/18/2017)... KALAMAZOO, Mich. , Sept. 18, 2017  PMD ... OptiMed Specialty Pharmacy of Kalamazoo, Mich. ... strategic hub service that expedites and streamlines patient and ... Spiro PD 2.0, and wellness management services.  ... medical device used to measure lung function for a ...
(Date:9/13/2017)... 13, 2017   OrthoAtlanta has been named the ... Host Committee (AFHC) for the 2018 College Football Playoff (CFP) ... at Mercedes-Benz Stadium in Atlanta, Georgia . ... "I,m In" campaign, participating in many activities leading up to, ... ...
Breaking Medicine Technology: