Navigation Links
NIAID announces vaccine adjuvant discovery contracts
Date:10/8/2009

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded six new research contracts to discover and characterize novel adjuvants, substances that can be added to vaccines to enhance the protective immune response they induce.

"The goal of these awards is to find safe new adjuvants that will boost the effectiveness of vaccines," says NIAID Director Anthony S. Fauci, M.D. "Adjuvants can be used not only to enhance the immune response to a vaccine and thereby offer better protection but also to extend the vaccine supply if needed, enabling more people to be vaccinated with fewer doses."

Currently, the only vaccine adjuvant approved for use in the United States is an aluminum mixture known as alum.

NIAID has awarded a total of approximately $60 million over five years for these contracts. The awardees will identify novel compounds with the potential to be vaccine adjuvants. All compounds will be tested in animal models and human cells to determine how well they stimulate the immune response. The investigators also will examine and describe the cellular reactions the compounds induce.

"The goal of these awards is not only to identify new adjuvant candidates but also to describe how these candidates work," says Helen Quill, Ph.D., chief of NIAID's basic immunology research branch. "We would hope that these adjuvant candidates will become part of a robust pipeline leading to the development of many different vaccines."

The awardees of the adjuvant contracts will work to identify and characterize novel adjuvants that trigger receptors of the inborn, or innate, immune system. These receptors recognize and bind small molecules that are unique to harmful microorganisms. Binding stimulates an immediate innate immune response, a broadly protective reaction. The innate immune response also is required for the development of the highly specific antibody and T-c
'/>"/>

Contact: Julie Wu
wujuli@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Rib-X Pharmaceuticals Receives Award from NIAID to Develop Antibiotic Treatment for Gonorrhea
2. NIAID launches 2009 H1N1 influenza vaccine trial in pregnant women
3. NIAID funds clinical trials that address the problem of antimicrobial resistance
4. NIAID Awards New Grant to Expand Studies of Peregrines Anti-PS Antibodies to Treat Viral Hemorrhagic Fevers
5. NIAID to fund new human immune profiling research centers
6. NIAID media availability: Still searching for predictors of asthma attacks
7. NIAID set to launch clinical trials to test 2009 H1N1 influenza vaccine candidates
8. NIAID media availability: New strategy proposed for designing antibody-based HIV vaccine
9. J. Craig Venter Institute Awarded $43 Million, Five Year Contract From NIAID to Continue to Develop and Provide Sequencing, Genotyping, and Bioinformatics Expertise and Services in Infectious Diseases
10. NIAID and Chinese officials sign agreement to foster TB research in Chinas Henan province
11. NIAID honors AIDS activist Martin Delaney
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... Fort Myers, FL (PRWEB) July 25, 2014 ... Apple iPhones, iPods, and iPads. The app provides a ... preventing painful and potentially dangerous sunburns and skin damage. ... about the sights, sounds, and capabilities of iTanSmart. ... by describing the app as a ‘better organized’ and ...
(Date:7/25/2014)... Silver®Care , for the first time ... silver that naturally kill oral bacteria and airborne bacteria from ... A toothbrush is the most common and important device in ... it is subject to constant contamination by bacteria found in ... bacteria in the mouth than anywhere else in the human ...
(Date:7/24/2014)... Miami, FL (PRWEB) July 25, 2014 ... Field National Championships but the incredible high jump by ... in Sacramento this past June, the USATF National Championships ... their sport. Zensah® athlete, Inika McPherson, won US Nationals ... set a new World Record for the biggest height ...
(Date:7/24/2014)... 25, 2014 Voted one of the ... global clients, BellasDress focuses on providing its new and ... information. Recently, the company has announced its new collection ... new range is created according to the latest fashion ... up to 68% off. , As a matter of ...
(Date:7/24/2014)... New York (PRWEB) July 24, 2014 ... lawsuits ( http://www.injurybeacon.com/granuflo-dialysis/lawsuit/ ) in the U.S. ... qualified protective order for plaintiff medical information covered ... Act. According to the July 16th Order, U.S. ... attorneys for Fresenius Medical Care the right ...
Breaking Medicine News(10 mins):Health News:iTanSmart® Suntan App by UV Technologies, LLC Gets a ‘Big Thumbs Up’ from New York Times App Smart Columnist, Kit Eaton 2Health News:iTanSmart® Suntan App by UV Technologies, LLC Gets a ‘Big Thumbs Up’ from New York Times App Smart Columnist, Kit Eaton 3Health News:Silver®Care’s New Silver Antibacterial Toothbrushes Naturally Kill Oral Germs 2Health News:Silver®Care’s New Silver Antibacterial Toothbrushes Naturally Kill Oral Germs 3Health News:Setting A New High Jump World Record In Zensah® Compression 2Health News:Setting A New High Jump World Record In Zensah® Compression 3Health News:BellasDress Helps Brides Get High End Wedding Dresses for Their Romantic Weddings 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4
... and roll,artist Chubby Checker, who lost mother to ... the world to the "Twist," in 1959, provided ... Cancer with a dose of the,oldies and an ... reward for,raising almost one million dollars Sunday. ...
... and television series M*A*S*H* featured the song Suicide is ... that being victimized because of sexual orientation is a ... and bisexual college students., , The study is the first ... among college students. In the course of the ...
... Accuray,Incorporated (Nasdaq: ARAY ), a global leader ... and CEO, Euan S. Thomson, Ph.D., is,scheduled to present ... at the Grand Hyatt Hotel in New York City, ... A live webcast of the presentation will be available ...
... 24 Enova Medical Technologies,and Stille AB (listed ... that,they have entered into a strategic marketing and ... Stille will market Enova,s,breakthrough LED cordless headlights to ... Britain and Italy and, on a non-exclusive,basis, throughout ...
... WESTLAKE VILLAGE, Calif., Sept. 24 Rush-Copley ... in Aurora, Ill., has,been recognized for service ... Hospital Program(SM). This distinction acknowledges a strong,commitment ... patients with an,"Outstanding Inpatient Experience." (Logo: ...
... JDR Features Editorial in October Issue, ALEXANDRIA, ... October issue of the Journal of Dental Research ... and Human Development.",Written by International Association for Dental ... John S. Greenspan, both from the,Department of Orofacial ...
Cached Medicine News:Health News:Victimization for sexual orientation increases suicidal behavior in college students 2Health News:Victimization for sexual orientation increases suicidal behavior in college students 3Health News:Stille and Enova Form Strategic Partnership to Introduce World's Brightest LED Cordless Surgical Headlights Into Europe and Japan 2Health News:J.D. Power and Associates Reports: Rush-Copley Medical Center Recognized for Third Consecutive Year for Providing an Outstanding Inpatient Experience 2Health News:J.D. Power and Associates Reports: Rush-Copley Medical Center Recognized for Third Consecutive Year for Providing an Outstanding Inpatient Experience 3Health News:Dental Researchers Participate in Global Awareness Initiative 2
(Date:7/24/2014)... MINNEAPOLIS, July 24, 2014  Uroplasty, Inc. (NASDAQ: ... develops, manufactures and markets innovative proprietary products to ... the fiscal 2015 first quarter ended June 30, 2014.  ... ®  PC Neuromodulation System grew 19% to $4.1 ... first quarter of the prior year.  Total revenue ...
(Date:7/24/2014)... 24, 2014 Omnicell, Inc. (NASDAQ: ... and supply management solutions and analytics software for ... 31, to discuss the Company,s Second Quarter 2014 ... 2014 earnings conference call and webcastWhen: , ... Lipps, chairman, president and chief executive officer ...
(Date:7/24/2014)... 24, 2014  Alimera Sciences, Inc. (NASDAQ: ... the research, development and commercialization of prescription ophthalmic pharmaceuticals, ... of fiscal year 2014 financial results after the market ... call will follow on the same day at 4:30 ... be hosted by Dan Myers , President and ...
Breaking Medicine Technology:Uroplasty Reports Fiscal First Quarter Results 2Uroplasty Reports Fiscal First Quarter Results 3Uroplasty Reports Fiscal First Quarter Results 4Uroplasty Reports Fiscal First Quarter Results 5Uroplasty Reports Fiscal First Quarter Results 6Uroplasty Reports Fiscal First Quarter Results 7Uroplasty Reports Fiscal First Quarter Results 8Uroplasty Reports Fiscal First Quarter Results 9Uroplasty Reports Fiscal First Quarter Results 10Uroplasty Reports Fiscal First Quarter Results 11Omnicell to Release Second Quarter 2014 Earnings Results on July 31 2Alimera Sciences To Release Second Quarter 2014 Results 2
... EyeScience(TM) ( www.eyescience.com ) announced today that ... and Dry Eye Formula(TM) are the only ... from their offices and through mass market retail. This announcement ... growing demand for the most complete eye vitamins available for ...
... (Nasdaq: HOLX ) today announced that Jack Cumming, Chairman, ... London on Tuesday, December 1, 2009, at 11:15am (GMT). ... audio webcast of Hologic,s investor presentation on the investor section ... An archive of the presentation will be available for replay ...
Cached Medicine Technology:EyeScience(TM) Announces New Program to Improve Patient Compliance and Practice Profits 2EyeScience(TM) Announces New Program to Improve Patient Compliance and Practice Profits 3
... Stryker Inter-Lock™ System provides fixation ... the tibial fixation site. Inter-Lock™ ... into one implant. It provides ... be used routinely where the ...
The Stryker Bioabsorbable Wedge Interference Screw is made of Poly-L Lactic Acid (PLLA). The patented wedge design makes it perfect for cruciate reconstruction and is indicated for BTB and soft tissu...
The Stryker Graft Workstation offers the surgeon flexibility in graft preparation. The posts are interchangeable and the system adapts to both soft tissue and bone grafts selection. Sizing gauges off...
... Knot Pusher is a reusable instrument used to ... Pusher is utilized in the handling and manipulation ... piece shaft allows the surgeon to place the ... The ring handle allows the surgeon ease of ...
Medicine Products: