Navigation Links
NHLBI funds research to improve safety of red blood cell transfusions
Date:6/21/2010

at optimize tissue oxygen delivery in transfusion recipients."

Blood breaks down the longer it is stored. Some red blood cells disassociate, releasing their hemoglobinthe iron-rich protein that carries oxygen. The free hemoglobin joins a growing collection of microparticles, white blood cell residues, and other byproducts that are contained in a fluid called the supernatant. Many of the red blood cells that stay intact develop membrane damage and lose their flexibility. Research is needed to determine whether such physical and biochemical changes adversely affect patients who receive stored blood.

In addition, researchers have yet to tease apart the effects of blood storage, blood components, the amount of blood transfused, genetics, and illness or injury on the patient's health after a transfusion. For instance, people with sickle cell disease, the blood disease thalassemia, and other chronic conditions that require frequent transfusions are at higher risk of transfusion complications.

"Until now, few projects have tried to distinguish complications that may result from the patient's underlying illness from those that may arise from the transfusions themselves," said Glynn.

The findings could open opportunities for personalized transfusions, where blood products could be manipulated based on a person's specific disease or characteristics. For example, if researchers discover that people with sickle cell disease suffer complications from a certain component of transfused blood, then those patients could be given red blood cell transfusions devoid of that component.

The eight grants are:

  • "Storage lesion in banked blood due to disruption of nitric oxide homeostasis," Mark Gladwin, M.D., University of Pittsburgh, and Daniel Kim-Shapiro, Ph.D., Wake Forest University, Winston-Salem, N.C. This team proposes that transfusion damage from stored blood can be traced to reduced levels of nitric oxi
    '/>"/>

Contact: NHLBI Communications Office
NHLBI_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. NHLBI funds preclinical tests on devices for infants and children with congenital heart defects
2. NHLBI, CDC launch surveillance and research program for inherited blood diseases
3. NIH/NHLBI-funded PACT Group Announces the Renewal of Production Assistance for Cellular Therapies (PACT)
4. NIH/NHLBI-Funded PACT Program Announces Webcast Scheduled for Tuesday, May 4, 2010, 2:00-4:00 pm ET
5. NHLBI to hold workshop on health consequences of sickle cell trait
6. Former Marine in Fight for Life to Raise Funds for Double Lung Transplant
7. Esperanza Health Center Receives $6.5 Million in Stimulus Funds
8. Wound treatment wins commercialization funds
9. Injury Funds Now To the Rescue with New Lawsuit Funding Service
10. Southridge Funds Facilitate Special Capital Distribution for Technest Shareholders
11. Salon Leau to Host Cuts for a Cause to Raise Funds and Spread the Word About Childhood Terminal Illnesses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... ... 04, 2015 , ... Bayco Products, Inc. announces a new industrial-grade LED Dual-LightTM ... hard hats that have a flip-up face shield. The sleek contours of the new ... having to remove their headlamp when raising or lowering their face shield or visor. ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... Worldwide Power Products is expanding its reach in Texas. Effective July 1st of ... Systems North Texas generator division. With the North Texas acquisition, Worldwide Power ...
(Date:8/4/2015)... ... ... One of the nation’s leading experts in chronic pain management has scheduled ... , which provides strategies for people who suffer from chronic pain. Dr. Mel ... the book in conjunction with Katherine Ketcham, an author who specializes in writing about ...
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... They say ... better understand certain health conditions, pictures and medical art can be essential. StayWell, a ... providers. , Krames Patient Education solutions have been used by physicians and other ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... product packaging, and fulfillment services, joined over 200 other Long Island-based corporations as ... on Tuesday, July 28th at Jones Beach State Park in Wantagh, New York. ...
Breaking Medicine News(10 mins):Health News:New Nightstick® NSP-4614B Dual-LightTM Headlamp fits more functionality into more places 2Health News:New Nightstick® NSP-4614B Dual-LightTM Headlamp fits more functionality into more places 3Health News:North Texas Acquisition Press Release 2Health News:Medical Expert's New Book Offers Help for Chronic Pain Sufferers 2Health News:Medical Expert's New Book Offers Help for Chronic Pain Sufferers 3Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 2Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 3Health News:NutraScience Labs "Steps Up" to the 2015 Marcum Workplace Challenge 2
... Impacts of the Program on Patients & Businesses Nationwide ... Health and Human ServicesWASHINGTON, April 16 In a ... of Congress urged the White House Office of Health ... the U.S. Department of Health and Human Services to ...
... sensor that can take readings at will , , THURSDAY, ... check your blood pressure with a quick glance at ... Technology (MIT) have produced a prototype of such a ... current blood pressure-monitoring systems. , "A wearable blood pressure ...
... for a Cause, Jill Davis TOAST, and HeartBeat 5000 Combine ... ST. PAUL, Minn., April 16 A series of events ... Hospitals and Clinics of Minnesota. Cocktails for a Cause ... first of three events organized by patient families to support ...
... April 16 The "Help is Here ... week of April 20 - April 24 at various cities ... on programs that provide prescription medicines for free or nearly ... above the national average of 8.5 percent, the Partnership for ...
... be held Wednesday, September 16, 2009 LOS ANGELES, ... Entertainment, will be honored at the 35th annual Dinner ... Chapter of the National Multiple Sclerosis Society. The ... 2009 at the Century Plaza Hotel in Los Angeles. ...
... Boosting registration critical to solving shortages, experts say , , THURSDAY, ... to donate their organs, but only 38 percent of licensed ... , Nearly 72 percent of Americans said they wanted to ... according to an online survey of 5,100 U.S. adults conducted ...
Cached Medicine News:Health News:84 Members of Congress, Led by Rep. Betty Sutton, Urge Policymakers to Rescind Controversial Medicare 'Competitive' Bidding Rule Before April 18 Deadline 2Health News:84 Members of Congress, Led by Rep. Betty Sutton, Urge Policymakers to Rescind Controversial Medicare 'Competitive' Bidding Rule Before April 18 Deadline 3Health News:84 Members of Congress, Led by Rep. Betty Sutton, Urge Policymakers to Rescind Controversial Medicare 'Competitive' Bidding Rule Before April 18 Deadline 4Health News:84 Members of Congress, Led by Rep. Betty Sutton, Urge Policymakers to Rescind Controversial Medicare 'Competitive' Bidding Rule Before April 18 Deadline 5Health News:A Blood Pressure Monitor to Wear on Your Wrist 2Health News:A Blood Pressure Monitor to Wear on Your Wrist 3Health News:Children's Hospitals and Clinics of Minnesota Launches Series of Events to Benefit Cardiac Care 2Health News:Children's Hospitals and Clinics of Minnesota Launches Series of Events to Benefit Cardiac Care 3Health News:Partnership for Prescription Assistance Prepared to Help Indiana Workers Hurt by Recession 2Health News:Partnership for Prescription Assistance Prepared to Help Indiana Workers Hurt by Recession 3Health News:The National Multiple Sclerosis Society's 35th Annual Dinner of Champions to Honor Summit Entertainment's Rob Friedman 2Health News:Survey Shows Many Want to Donate Organs, But Few Do 2
(Date:8/4/2015)... SAN FRANCISCO , Aug. 4, 2015 /PRNewswire/ ... Nicki Vasquez , Ph.D., as vice president ... have a leadership role in the management of ... cancer therapeutics pipeline, including antibody-drug conjugates, bispecific antibodies ... Dr. Vasquez brings more than 22 years of ...
(Date:8/4/2015)... -- Concord Medical Services Holdings Limited ("Concord Medical", or the ... and operator of the largest network of radiotherapy and diagnostic ... it will release its financial results for the second quarter ... Management will hold a conference call to discuss ... August 18, 2015 (8:00 p.m. in Beijing ...
(Date:8/4/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/nl392k/alcohol ) ... Market by Application (Household & Personal Care, Pharmaceutical, Oilfield, ... to 2019" report to their offering. ... at $5,124.9 million in 2014 and is projected to ... to 2019. The data mentioned in the report is ...
Breaking Medicine Technology:Sutro Biopharma Appoints Nicki Vasquez, Ph.D. as VP of Alliance and Project Management 2Concord Medical to Report Second Quarter 2015 Financial Results on August 17, 2015 2Global Alcohol Ethoxylate Market 2015 - Market Trends, Forecasts to 2019 for the $5.1 Billion Industry 2Global Alcohol Ethoxylate Market 2015 - Market Trends, Forecasts to 2019 for the $5.1 Billion Industry 3
... Calif., April 11, 2011 Masimo ... a new study published in this month,s issue of ... that pulse oximetry makes a critical difference in neonatal ... measurements.  In comparing the measurement response times of three ...
... A survey of home medical equipment companies ... to Medicare beneficiaries have made abrupt changes in their ... regulatory changes have made it difficult for some businesses ...     The American Association for Homecare ...
Cached Medicine Technology:New Published Study Finds Masimo SET® Delivers More Reliable Measurements Significantly Faster Than Other Pulse Oximetry Technologies 2New Published Study Finds Masimo SET® Delivers More Reliable Measurements Significantly Faster Than Other Pulse Oximetry Technologies 3New Published Study Finds Masimo SET® Delivers More Reliable Measurements Significantly Faster Than Other Pulse Oximetry Technologies 4New Published Study Finds Masimo SET® Delivers More Reliable Measurements Significantly Faster Than Other Pulse Oximetry Technologies 5Survey Finds Mobility Providers Struggling to Adjust to New Medicare Policies and Regulations 2Survey Finds Mobility Providers Struggling to Adjust to New Medicare Policies and Regulations 3Survey Finds Mobility Providers Struggling to Adjust to New Medicare Policies and Regulations 4Survey Finds Mobility Providers Struggling to Adjust to New Medicare Policies and Regulations 5Survey Finds Mobility Providers Struggling to Adjust to New Medicare Policies and Regulations 6
... RFID to gather patient flow ... such as surgical and emergency ... of patient location to identify ... events have occurred and when ...
... Mobile Aspects Patient Tracking System enables ... of patient safety and to increase throughput ... web-based interface. , The system utilizes Mobile ... fit into a patient wrist band, and ...
MONOJECT MAGELLAN Safety Blood Collection Needle...
... Blood Collection Needles are preominantly used for ... single-use. The colour of the needle protective ... needle gauges. For example, yellow symbolises the ... 21 G (0.80 mm) and black 22 ...
Medicine Products: