Navigation Links
NEJM study demonstrates carotid stenting with embolic protection is comparable to surgery
Date:4/10/2008

WARREN, N.J., April 9, 2008 According to a study published in The New England Journal of Medicine this week, three-year data from the Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) study in patients with severe blocked carotid arteries, the main blood vessels in the neck leading to the brain, who underwent carotid artery stenting (CAS) with the PRECISE Nitinol Stent and the ANGIOGUARD Emboli Capture Guidewire were comparably protected from stroke, heart attack, death, and repeat revascularization procedures as patients who underwent surgery (endarterectomy).

SAPPHIRE is a multicenter, prospective, randomized study that evaluated the safety and performance of the PRECISE Nitinol Stent and ANGIOGUARD Emboli Capture Guidewire, compared with endarterectomy, in 334 patients with high-grade carotid artery stenosis. The prespecified major secondary endpoint at three years was a composite of death, stroke, or myocardial infarction within 30 days after the procedure or death or ipsilateral stroke (occurring on the same side) between 31 days and three years.

At three years, data were available for 260 patients, 85.6 percent of patients (143 of 167) in the stenting group and 70.1 percent of patients (117 of 167) in the surgery group. The pre-specified major secondary endpoint occurred in 41 of the 167 patients who underwent stenting (cumulative incidence, 24.6 percent) and in 45 of 167 patients who underwent endarterectomy (cumulative incidence, 26.9 percent). There was no statistical significance between these groups. A procedure to re-open the blocked arteries (target-vessel revascularization) was infrequent in both groups.

It is important to know the protection of carotid revascularization against future stroke and other ischemic events was maintained at three years and there was no significant difference in the cumulative incidence of major cardiovascular events between carot
'/>"/>

Contact: Amy Meshulam
amy.meshulam@edelman.com
323-202-1028
Edelman Public Relations
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... 27, 2015 Cincinnati Veterans Affairs Women’s Health ... Veterans (CERV) Foundation is proud to host the first annual ... Veterans June 11 at the Freedom Center from 6 p.m. ... be the emcee. , This event honors and celebrates ... nation. The banquet is free to the first 150 ...
(Date:5/27/2015)... May 27, 2015 Genius Monkey is ... advanced programmatic marketing technology, they have boosted sales for ... on a regional level for seven Utah-based dealers. ... through television and radio media. In 2014 the Utah ... help of Genius Monkey , shifted their marketing ...
(Date:5/27/2015)... CA (PRWEB) May 27, 2015 With ... total communication environment where the message is not only heard ... toy, drawing, or virtually any motivating image. This award-winning and ... to offer. , Now, using InnerVoice Sender app ... can be sent to a learner remotely for no additional ...
(Date:5/27/2015)... May 27, 2015 With a prevalently ... poll conducted during the "ACA - Controlling the Chaos" ... 75% are currently in the process of researching ... were confidently prepared for the reporting mandates. , According ... the webinar, those who are currently vetting ACA reporting ...
(Date:5/27/2015)... SmarterSkin, http://www.smarterskindermatology.com , is taking skin care ... makes it easier for patients to find skin care products ... Sejal Shah is a cosmetic dermatologist based in New York ... test. This revolutionary DNA test uses 16 genetic markers to ... , 1. Firmness and elasticity , 2. Glycation , ...
Breaking Medicine News(10 mins):Health News:Cincinnati VA Women’s Health Clinic Celebrates Women Veterans at Awards Banquet 2Health News:Genius Monkey Boosts Utah Honda Dealers Website Traffic 142% 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 3Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 4Health News:Employers are On Track for ACA Reporting According to Businessolver Poll 2Health News:SmarterSkin Dermatology is Now Offering Skin DNA Analysis 2
... with language problems might have a lot in common with ... Impairment (SLI) // and they feel that these findings could ... best treatments for individual components of the condition. ,Researchers ... key language center in the brain -- in autistic boys ...
... your child at bedtime would be a pitch-black room as ... risk for leukemia.// ,In the past, research has ... for breast cancer, further supporting the theory that light at ... determined that light at night is found to disrupt the ...
... loss may also help prevent prostate cancer from spreading. A ... spread of cancer to the bone and reduce the risk ... bone loss. ,Estimates show prostate cancer spreads to the ... 311 men who were being given hormone therapy for bone ...
... worth of data on breast cancer patients , researchers say ... at diagnosis and those who are diagnosed at a younger ... to die from the disease. Black women are also more ... are those whose tumors are negative for the estrogen receptor. ...
... 2 diabetes could benefit from statins to reduce their risk ... benefits of statin therapy to reduce cardiovascular disease in // ... diabetics who are at an increased cardiovascular risk would benefit ... to look at the effectiveness of statin therapy among type ...
... who have implanted heart-assist devices, such as pacemakers ... .// ,Pacemakers and defibrillators are battery-operated implantable ... as arrhythmia. Researchers say doctors have feared that ... up metal components of the device, dislodge it, ...
Cached Medicine News:
(Date:5/27/2015)... -- Actavis plc (NYSE: ACT ) announced today ... and Drug Administration (FDA) as a twice-daily, oral ... with diarrhea (IBS-D). VIBERZI (eluxadoline) has mixed opioid ... a delta receptor antagonist, and a kappa receptor ... "The FDA,s approval of VIBERZI is ...
(Date:5/27/2015)... , May 27, 2015 OpportunityAnalyzer: Sepsis ... Sepsis patients suffer from a series of diverse ... toxins in the blood or tissues, which cause a ... leading to mortality rates near 50% depending on disease ... national healthcare systems of the global marketplace, which for ...
(Date:5/27/2015)... May 27, 2015 The prevalence of cardiovascular ... accelerated aging of population and changes in consumption concept, ... been growing year after year, thereby promoting the development ... in China totaled 454,505 in ... interventional cardiovascular device industry there was worth RMB20.12 billion. ...
Breaking Medicine Technology:Actavis Receives FDA Approval for VIBERZI (eluxadoline) for the Treatment of Irritable Bowel Syndrome with Diarrhea (IBS-D) in Adults 2Actavis Receives FDA Approval for VIBERZI (eluxadoline) for the Treatment of Irritable Bowel Syndrome with Diarrhea (IBS-D) in Adults 3Actavis Receives FDA Approval for VIBERZI (eluxadoline) for the Treatment of Irritable Bowel Syndrome with Diarrhea (IBS-D) in Adults 4Actavis Receives FDA Approval for VIBERZI (eluxadoline) for the Treatment of Irritable Bowel Syndrome with Diarrhea (IBS-D) in Adults 5OpportunityAnalyzer: Sepsis - Opportunity Analysis and Forecasts to 2021 2OpportunityAnalyzer: Sepsis - Opportunity Analysis and Forecasts to 2021 3OpportunityAnalyzer: Sepsis - Opportunity Analysis and Forecasts to 2021 4China Interventional Cardiovascular Device Industry Report, 2014-2017 2China Interventional Cardiovascular Device Industry Report, 2014-2017 3
... Alere Health, LLC announced today that it has ... Health Information Products Certification for Health Information Line. ... a 24/7 nurseline staffed by highly experienced, registered ... decisions by providing immediate clinical support for everyday ...
... BOTHELL, Wash., April 6, 2011 BioLife Solutions, Inc. ... grade biopreservation media products for cells and tissues, today ... ended March 31, 2011. This represents 6% sequential growth ... growth from the first quarter of 2010.   ...
Cached Medicine Technology:Alere Earns NCQA Health Information Products Certification for Health Information Line 2BioLife Solutions Announces Record Quarterly Revenue 2BioLife Solutions Announces Record Quarterly Revenue 3BioLife Solutions Announces Record Quarterly Revenue 4
... macular health. Snellen charts available ... Easy to mount on most ... in a few minutes. Rapid ... Retinal vision testing without refraction ...
Eye Q Lite is ideal for color and red-free imaging used in general clinical and optometric casework such as anterior segmenting and diabetic screening....
The Genesis Camera meets the needs of those with specific requirements that cannot be met by a conventional 'chinrest' type camera....
The quick access to diabetic screening, panoramic images of the retina including peripheral area are available by using easy, semi automatic guidance of peripheral fixation....
Medicine Products: