Navigation Links
NEJM publishes study showing LigoCyte's norovirus vaccine demonstrates protection against illness
Date:12/7/2011

ming clinical studies of the product."

Specifically, data from the study show:

  • In the 77 adults who completed the trial per its original protocol, vaccination decreased the incidence of gastroenteritis due to norovirus from 69.2 percent to 36.8 percent, a 47 percent reduction in illness compared to subjects receiving placebo (95% CI 15.2%-66.6%; p=.006).

  • Subjects receiving vaccine scored lower on a severity of illness scale (p=.011).

  • Immunization with the VLP vaccine increased antibody titers that blocked VLP binding to histo blood group antigens in vitro.

  • Higher functional antibody responses in all subjects correlated with increased protection against illness. A serum BT50 titer of 200 or greater was associated with a 72.2 percent reduction in virus-associated illness (odds ratio of 8.1 (95% CI 2.1-31.2)).

  • Adverse events occurred with similar frequency among vaccine and placebo subjects. The most common symptoms after vaccination included nasal congestion, stuffiness and sneezing.

About Norovirus Illness

Norovirus gastroenteritis is a widespread and potentially severe illness characterized by the acute onset of nausea, vomiting, abdominal cramps, diarrhea and occasionally fever. Noroviruses are highly infective and easily transmitted from person to person or via contaminated environments. Epidemic outbreaks occur in community environments, particularly hospitals, hotels, schools, day care facilities and nursing homes, with mounting socioeconomic cost to families, the health care system and businesses. Military units are significantly affected when the virus strikes, as outbreaks impact combat readiness. Severe clinical outcomes are reported in older adults, children and immunocompromised individuals in whom infection can lead to substantial complications and can even lead to death.

About the Phase I/II Norovirus Vaccine and Challenge Study

<
'/>"/>
Contact: Kari Watson
kwatson@macbiocom.com
781-235-3060
MacDougall Biomedical Communications, Inc.
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Canadian Journal of Cardiology publishes report on delayed vs. immediate coronary stenting
2. European Journal of Heart Failure publishes new randomized controlled clinical study of RESPeRATE
3. ASTRO publishes white paper on IMRT safety
4. EMAS publishes position statement about the post-reproductive health of women
5. ASTRO publishes evidence-based guideline for thoracic radiotherapy
6. Canadian Journal of Cardiology publishes advice on genetic testing of inherited cardiac arrhythmias
7. NYSCF - Robertson investigator publishes research to better understand pluripotent stem cells
8. ASTRO publishes palliative radiotherapy for bone metastases guideline
9. Practical Radiation Oncology publishes first issue
10. EMAS publishes position statements about the post-reproductive health of women
11. ASTRO publishes whole breast irradiation guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 22, 2015 Gabe’s Chemo Duck Program is pleased ... first app ever created for kids with cancer. The Chemo Duck ... devices, is filled with enjoyable games to help children of all ... free app helps to keep kids entertained, educated and at ease ...
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method put ... muscle by up to 30lbs in less than 12 weeks ... Stan Stevenson, prompting an investigative review. , “Our Incredible ... diet formula that allows the body to pack on a ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, ... dresses. View website of AngelWeddingDress.com to find ... wedding dresses online for a bridal party. AngelWeddingDress offers ... for them. Its maternity wedding dresses are specially designed ...
(Date:1/22/2015)... A new white paper by The ... in the long-term care environment as well as provides ... The paper, “The Power of Person-Centeredness in Long-Term Care: ... of the patient, resident and family experience in long-term ...
(Date:1/22/2015)... For over 20 years, Dr. David Cruz of Cruz ... has treated just about every type of injury that can result ... those same twenty-plus years, the team at Doctors on Liens ... best possible doctor. With the combined breadth of experience ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2
... eliminate rabies in dogs//., ,The vaccine, in the ... scientists at the High Security Animal Disease Laboratory (HSADL)., ... stray dogs due to its artificial taste enhancers - like ... inside the dog's mouth, the capsule bursts and the medicine ...
... Mount Sinai School of Medicine have just developed an ... microdomains of leukocytes// or white blood cells. Microdomains are ... which receptors and signaling molecules accumulate during cell activation. ... white blood cell subsets and their forming microdomains in ...
... An Indian American fitness guru has created a fusion of ... in the United States//. , ,Sarina Jain, also ... Bhangra' and is credited with the introduction of Bhangra, the ... ,Jain holds her aerobic classes all over the US, ...
... are increasingly at the risk of becoming infected with ... active TB disease//, according to an analysis of previously ... ,About one-third of the world’s population is infected with ... is usually rendered inactive by the immune system, according ...
... A recent report published by the Center for Science in ... served in popular hotels// are very high in calories. The ... increased a lot which is leading to many health issues ... the food and its nutritional information enable the consumer to ...
... Compendium of Health Statistics published by the Office of Health ... method. This is costing the NHS twice as much as ... the deliveries by C section have increased to 23.2%. There ... 1995 to 2006. There is an increase of emergency C ...
Cached Medicine News:Health News:New Imaging Technique Tracks Traffic Patterns of White Blood Cells 2Health News:Susceptibility to TB is High Among the Smokers 2
(Date:1/23/2015)... MYERS, Fla. , Jan. 23, 2015  Today the ... of Novartis, Bexsero® for the prevention of serogroup ... 25. Bexsero and Pfizer,s vaccine Trumenba®, which received FDA ... helping prevent this devastating disease. "I ...
(Date:1/23/2015)... to Fight Chronic Disease (PFCD) released a public opinion poll of ... study analyzing the impact of increased cost sharing on patient adherence ... educate policy makers and the public on the costs of chronic ... the Iowa healthcare exchange could be improved ...
(Date:1/23/2015)... than a third of reproductive-aged women enrolled in Medicaid, and ... a prescription for an opioid pain medication each year during ... Mortality Weekly Report (MMWR). Opioids are typically ... pain.  They are also found in some prescription cough medications. ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
... and Efficacy Data Presented at 1st IASLC-ESMO European Lung ... ... Poniard,Pharmaceuticals, Inc. (Nasdaq: PARD ), a biopharmaceutical company focused,on ... trial of picoplatin confirming previously announced interim,results showing a survival benefit ...
... Replidyne, Inc.,(Nasdaq: RDYN ) announced today that ... clinical trial testing faropenem medoxomil,(faropenem) in patients with ... action to conserve its cash assets and support,initiatives ... programs., The AECB study is one in ...
Cached Medicine Technology:Poniard Pharmaceuticals Announces Final Picoplatin Data from Phase 2 Small Cell Lung Cancer Trial Demonstrating Survival Benefit 2Poniard Pharmaceuticals Announces Final Picoplatin Data from Phase 2 Small Cell Lung Cancer Trial Demonstrating Survival Benefit 3Poniard Pharmaceuticals Announces Final Picoplatin Data from Phase 2 Small Cell Lung Cancer Trial Demonstrating Survival Benefit 4Replidyne Discontinues Phase III Trial 2Replidyne Discontinues Phase III Trial 3
The convenience of disposable type lenses available in a wide variety of options. Recommended replacement schedule: one week for extended wear, two weeks for daily wear....
Acuvue2 is designed to be worn as a two-week daily wear lens (which means you take the lenses out each night). It can also be worn as a one-week extended wear lens (which means you can sleep in them)...
... content spherical soft lens manufactured using ... for use in the correction of ... wear basis. The increased mid-peripheral thickness ... good handling across the power range. ...
... An easy-to-fit low water content spherical soft ... III" or cast molding technology, and designed ... and hyperopia on a daily wear or ... provides good oxygen transmission, while an increased ...
Medicine Products: