Navigation Links
NEJM publishes study showing LigoCyte's norovirus vaccine demonstrates protection against illness
Date:12/7/2011

ming clinical studies of the product."

Specifically, data from the study show:

  • In the 77 adults who completed the trial per its original protocol, vaccination decreased the incidence of gastroenteritis due to norovirus from 69.2 percent to 36.8 percent, a 47 percent reduction in illness compared to subjects receiving placebo (95% CI 15.2%-66.6%; p=.006).

  • Subjects receiving vaccine scored lower on a severity of illness scale (p=.011).

  • Immunization with the VLP vaccine increased antibody titers that blocked VLP binding to histo blood group antigens in vitro.

  • Higher functional antibody responses in all subjects correlated with increased protection against illness. A serum BT50 titer of 200 or greater was associated with a 72.2 percent reduction in virus-associated illness (odds ratio of 8.1 (95% CI 2.1-31.2)).

  • Adverse events occurred with similar frequency among vaccine and placebo subjects. The most common symptoms after vaccination included nasal congestion, stuffiness and sneezing.

About Norovirus Illness

Norovirus gastroenteritis is a widespread and potentially severe illness characterized by the acute onset of nausea, vomiting, abdominal cramps, diarrhea and occasionally fever. Noroviruses are highly infective and easily transmitted from person to person or via contaminated environments. Epidemic outbreaks occur in community environments, particularly hospitals, hotels, schools, day care facilities and nursing homes, with mounting socioeconomic cost to families, the health care system and businesses. Military units are significantly affected when the virus strikes, as outbreaks impact combat readiness. Severe clinical outcomes are reported in older adults, children and immunocompromised individuals in whom infection can lead to substantial complications and can even lead to death.

About the Phase I/II Norovirus Vaccine and Challenge Study

<
'/>"/>
Contact: Kari Watson
kwatson@macbiocom.com
781-235-3060
MacDougall Biomedical Communications, Inc.
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Canadian Journal of Cardiology publishes report on delayed vs. immediate coronary stenting
2. European Journal of Heart Failure publishes new randomized controlled clinical study of RESPeRATE
3. ASTRO publishes white paper on IMRT safety
4. EMAS publishes position statement about the post-reproductive health of women
5. ASTRO publishes evidence-based guideline for thoracic radiotherapy
6. Canadian Journal of Cardiology publishes advice on genetic testing of inherited cardiac arrhythmias
7. NYSCF - Robertson investigator publishes research to better understand pluripotent stem cells
8. ASTRO publishes palliative radiotherapy for bone metastases guideline
9. Practical Radiation Oncology publishes first issue
10. EMAS publishes position statements about the post-reproductive health of women
11. ASTRO publishes whole breast irradiation guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... Lexington, Kentucky (PRWEB) October 22, 2014 ... an agreement that will change the current location of ... Road to South Limestone across from the University of ... be a state-of-the-art ambulatory care center, owned and operated ... meet the orthopaedic needs of children and their families ...
(Date:10/22/2014)... Pass, OR (PRWEB) October 22, 2014 ... Southern California’s fresh water supply runs dangerously low, Southern ... change. Southern Oregon’s rivers, despite the lowest mountain snow ... even in late summer and early autumn.* That was ... authors of the new book “Hiking Southern Oregon,” during ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Although there are only ... time for many people who have trouble finding time within their ... to exercise for long periods of time to get in shape. ... goals while on the go. , Change Up Your Commute ... to work to add some exercise into your daily routine. If ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 (HealthDay ... be showing a genetic propensity for obesity as toddlers, a ... linked to increased body fat, but the same genes in ... researchers said. At 1 year, kids with these genes ... however, these genes were linked to excessive weight gain, the ...
(Date:10/22/2014)... HealthDay Reporter TUESDAY, Oct. 21, ... vitro fertilization (IVF) -- the incubation of embryos in a ... inside the vagina, new research suggests. Scientists from the ... INVOcell, might sharply cut costs for pricey IVF procedures among ... to those who don,t live near big-city assisted reproduction centers, ...
Breaking Medicine News(10 mins):Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 2Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 4Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4
... 3.3 percent of children aged 2 to 19 are below ... number of underweight children aged 2 to 19 in the ... percent in 2003-2006, says a U.S. government study. , Being ... , Researchers at the U.S. Centers for Disease Control and ...
... , MEQUON, Wis., July 15 ... Maryland, has been recognized as the 2nd annual Wonderbox Technologies "Super ... Wonderbox Technologies staff during a special ceremony at the GDS offices ... Technologies performed an internal review of its clients, end users and ...
... BEIJING, July 15 New Enterprise Associates (NEA), ... four of its China-based portfolio companies were named to ... LianLian Pay, LineKong and Novast Pharmaceuticals. Spanning consumer technology, ... selected underscore the growth potential within several key areas ...
... on understanding of dilated cardiomyopathy , WEDNESDAY, July 15 ... disease and chronic heart failure in some children and ... , Dilated cardiomyopathy -- the most common cause of ... reason for a heart transplant -- is a condition ...
... memory of 10 minutes at this stage in development ... are only 30 weeks old may already possess short-term ... step into a better insight in the development of ... Jan G. Nijhuis, director of the Centre for Genetics, ...
... , , ... Inc., a leading provider of software and services for health and human ... management software company based in Killeen, Texas. Terms of the agreement were ... Crown provides Netsmart with a pharmacy management software solution, RxConnect, that will ...
Cached Medicine News:Health News:Wonderbox Technologies(R) Announces 2nd Annual Super User of the Year 2Health News:NEA Portfolio Companies Selected as Zero2IPO Venture 50 and China Entrepreneur 'Rising Stars' Honorees 2Health News:NEA Portfolio Companies Selected as Zero2IPO Venture 50 and China Entrepreneur 'Rising Stars' Honorees 3Health News:Gene Mutation Is Linked to Heart Muscle Disease 2Health News:Memory Forms at 30 Weeks in the Womb 2Health News:Memory Forms at 30 Weeks in the Womb 3Health News:Netsmart Technologies Acquires Pharmacy Management Software Company 2Health News:Netsmart Technologies Acquires Pharmacy Management Software Company 3
(Date:10/22/2014)... , Oct. 22, 2014  With a vision ... health medications, a Global Pharmaceutical and Biotech manufacturer ... technology and turnkey solution to protect their animal ... http://photos.prnewswire.com/prnh/20141021/153438 Photo - ... was serialized and aggregated by the Xyntek and ...
(Date:10/22/2014)... 2014   BioNano Genomics , the genome ... centers to purchase an Irys™ System . Among ... Institute (NCI), NIH Intramural Sequencing Center (NISC) and Genoscope ... a comprehensive view of a genome was a ... not deliver the scalability or reliability to detect ...
(Date:10/22/2014)... Abaxis, Inc. (NasdaqGS: ABAX ), ... today reported financial results for the second fiscal quarter ... , Revenues of $53.9 million, up 18% over ... $0.24, up 33% over last year,s comparable quarter. ... Veterinary Reference Laboratories (AVRL) of $3.5 million, up 50% ...
Breaking Medicine Technology:Xyntek and Antares Serialization Solution Protects Pets Too! 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 2Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 3Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 4Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 5Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 6Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 7Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 8Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 9Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 10Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 11Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 12Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 13Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 14
... and local dignitaries ushered in a new chapter in ... of a laboratory complex designed to speed up cures ... housing 78 labs and other facilities, signifies a break ... different fields and allowing them to communicate more effectively. ...
... Sanofi Pasteur, the vaccines division of Sanofi (EURONEXT: SAN ... a new study examining the immunogenicity and safety profiles of ... and younger adults to a standard dose of Fluzone vaccine. ... the Infectious Diseases Society of America on October 21, 2011. ...
Cached Medicine Technology:MUSC Dedicates New Bioengineering and Drug Discovery Hubs 2Sanofi Pasteur Presents New Data Confirming Fluzone® High-Dose (Influenza Virus Vaccine) Produces Higher Antibody Response in the Age 65+ Population 2Sanofi Pasteur Presents New Data Confirming Fluzone® High-Dose (Influenza Virus Vaccine) Produces Higher Antibody Response in the Age 65+ Population 3Sanofi Pasteur Presents New Data Confirming Fluzone® High-Dose (Influenza Virus Vaccine) Produces Higher Antibody Response in the Age 65+ Population 4Sanofi Pasteur Presents New Data Confirming Fluzone® High-Dose (Influenza Virus Vaccine) Produces Higher Antibody Response in the Age 65+ Population 5Sanofi Pasteur Presents New Data Confirming Fluzone® High-Dose (Influenza Virus Vaccine) Produces Higher Antibody Response in the Age 65+ Population 6
... Microvolume technology , The ADVIA 1650 has ... as 2 L/test), reagent consumption (as low ... L/hour) - thus maximizing management efficiency. , ... cycle and system throughput of up to ...
... and controls interchangeable with other Roche/Hitachi ... training costs. Consistent patient results throughout ... handling. 70 positions for routine, STAT ... volumes. Intermix sample types. Intermix 5 ...
With the sample processing core unit and intelligent process management, combines a wide variety of analytical modules to enable full consolidation of clinical chemistry and immunochemistry....
... The Roche Diagnostics Task ... a state-of-the-art automation of ... the laboratories: decapping, sorting / ... aliquoting into bar code labeled ...
Medicine Products: