Navigation Links
NCI renews Fox Chase/Penn Ovarian Cancer 'SPORE' grant for a third 5-year term
Date:9/4/2009

ase, and Timothy Rebbeck, M.D., Penn.

While well known for their involvement in breast cancer, mutations in the BRCA1 and BRCA2 genes whether inherited or acquired -- also contribute to ovarian cancer. The risk of these mutations, and how to counsel BRCA1/2 mutation carriers, is less well understood. The team lead by Daly and Rebbeck seeks to identify extent of risk factors related to BRCA1/2-associated ovarian cancers and to develop a methodology by which to counsel carriers of the mutation on treatment options including prophylactic removal of the ovaries.

3. Therapeutic Micro RNA Strategies for Ovarian Cancer, co-lead by Lin Zhang, M.D., and Peter. O'Dwyer, M.D. from Penn, and Thomas Hamilton, Ph.D., of Fox Chase

Malignant epithelial ovarian cancer is one of the most common and lethal forms of ovarian cancer. While new therapies have led to increased survival, these patients typically relapse within a few years with a more resistant form of the disease. Recently, the Penn SPORE investigators have found evidence that microRNAs tiny segments of RNA have a role in ovarian cancer and could serve as a biomarker for early diagnosis. These microRNAs, which usually help regulate how genes are read, or expressed, are often themselves deregulated in ovarian cancer. Therefore, the researchers believe that microRNAs might be able to help restore the regulation of genes in ovarian cancer and might serve as a therapeutic or enhance the effect of chemotherapy.

4. Targeting Signaling Networks Via Novel RNAi Approaches to Improve Therapy for Ovarian Cancer, co-lead by Fox Chase researchers Andrew Godwin, Ph.D., Erica Golemis, Ph.D., and Russell Schilder, M.D.

While a single genetic mutation might initiate cancer, most tumors have evolved multiple mutations by the time the cancer is diagnosed. This team of researchers plans to use so-called silencing RNA (siRNA) technology to piece together the effects of silencing individual cancer gen
'/>"/>

Contact: Greg Lester
gregory.lester@fccc.edu
215-728-2753
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Wacoal Renews Successful Support the Girls Program
2. Coalition America Renews Relationship with Musketeer to Offer Streamlined Claims Repricing and Adjudication Solution for Benefit Administrators
3. NIH/NCI renews and extends nationwide license for Genomatix software and databases
4. Sanofi-Aventis renews licenses for Genomatix chip analysis pipeline
5. Independence Technology, A Johnson & Johnson Company, Renews Its Contract With Creative Technology Services
6. Acclamation Systems, Inc. Renews Partnership with Coalition America to Offer Streamlined Repricing and Adjudication Solution
7. FDA Renews Warnings on Pain-Relief Patch
8. Heart Association Renews Call for CPR Training
9. ABQAURP Renews Agreement with the National Board of Medical Examiners to Oversee Testing Methodology
10. FDA Renews its Contract with Beaumont Technology Usability Center for Leadership of Patient Safety Project
11. Governor Rendell Says 2008-09 Budget Renews Commitment to Vulnerable Pennsylvanians
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... As the age of marriage and ... as a way to ensure future family building options ... advancing reproductive age. Vitrification technology, a fast freeze method ... technology that allows a woman to have multiple eggs ... which are then stored for future use. When circumstances ...
(Date:7/24/2014)... scientists at Carnegie Mellon University, working with high-throughput ... Berkeley National Laboratory, have devised a computational method ... normal breast cells turn malignant and as they ... for analyzing how genes interact with each other ... published today by the online journal PLOS ...
(Date:7/24/2014)... 2014 In a recent report by CBS ... put an end to criminal penalties associated with possession of ... for marijuana reform in Washington DC, giving it one of ... replaces criminal penalties for possession of one ounce of marijuana ... possession of more than an ounce of marijuana remain criminal ...
(Date:7/24/2014)... from Penn Medicine shows that incisionless transcatheter aortic ... stay by 30 percent and has no impact ... conventional transfemoral TAVR, which requires an incision in ... the current issue of Circulation: Cardiovascular Interventions ... aortic valve without a traditional open-heart surgical approach. ...
(Date:7/24/2014)... PROVIDENCE, R.I. Lynn E. Taylor, M.D., director ... states in the July, 2014 Rhode Island ... C" that eliminating hepatitis c virus infection (hep ... benefits, enhance capacity to address other health challenges, ... HCV in the United States, Taylor says, include ...
Breaking Medicine News(10 mins):Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 2Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 3Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 4Health News:Gene changes in breast cancer cells pinpointed with new computational method 2Health News:Gene changes in breast cancer cells pinpointed with new computational method 3Health News:Washington D.C. Decriminalizes Marijuana 2Health News:Penn study: Incisionless transcatheter aortic valve replacement surgery cuts hospital length of stay 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 3Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 4
... , FRIDAY, March 25 (HealthDay News) -- A small army ... of sick and dying animals from a rural North Carolina ... More than 400 animals -- 17 species in all, ... had been living in squalor with a middle-aged couple claiming ...
... FRIDAY, March 25 (HealthDay News) -- People looking for a ... joints sometimes turn to biking. Rather than a 30-minute jog ... hours on the bike, with little or no joint strain. ... physical activity raise a new problem: How to keep the ...
... Aurora, Colo. (March 24, 2011)A research team at the University ... be used to diagnose colon cancer earlier. It is possible ... the cancer. Colon cancer is the third most common cancer ... it, according to the American Cancer Society. This enzyme biomarker ...
... The US Food and Drug Administration announced today that ... the treatment of patients with metastatic melanoma. It is the ... with advanced melanoma. Ipilimumab uses a novel approach known ... attack cancer. The therapy, originally known as anti-CTLA-4, was developed ...
... Research Chair Peter Shizgal who investigates the roots ... recognized by his peers with the prestigious Prix Adrien ... Psychology and a member of the Centre for Studies ... qubcoise pour la recherche en psychologie (Quebec Society for ...
... , FRIDAY, March 25 (HealthDay News) -- A poor diet ... postmenopausal women, a new study has found. Researchers analyzed ... found that deficiencies in more than a single nutrient were ... Risk increased 44 percent with deficiencies in three nutrients. ...
Cached Medicine News:Health News:Animal 'Hoarding' Often Tied to Mental Illness 2Health News:Animal 'Hoarding' Often Tied to Mental Illness 3Health News:Animal 'Hoarding' Often Tied to Mental Illness 4Health News:Cyclists Urged to Prep Their Bodies for the Long Haul 2Health News:Cyclists Urged to Prep Their Bodies for the Long Haul 3Health News:University of Colorado team identifies new colon cancer marker 2Health News:Novel immunotherapy drug receives FDA approval for the treatment of metastatic melanoma 2Health News:Peter Shizgal distinguished by his peers 2Health News:Poor Eating Habits May Lead to Anemia in Older Women 2
(Date:7/24/2014)... -- Delivery of the Report will take 2-3 ... Photo - http://photos.prnewswire.com/prnh/20140723/129707 ... on Global and Chinese Hemodialysis Machine industry. The ... Machine including its classification, application and manufacturing technology. ... manufacturers of Hemodialysis Machine listing their product specification, ...
(Date:7/24/2014)... 24, 2014 Cancer patients in the west of ... cancer treatment closer to home when a new radiotherapy center ... Medical Systems (NYSE: VAR ) has been selected ... in June for four TrueBeam™ medical linear accelerators. ... and efficient radiotherapy and radiosurgery treatments, will replace older treatment ...
(Date:7/24/2014)... July 24, 2014  Blueprint Medicines (Blueprint), a leader ... cancer patients, today announced the appointment of Jeffrey ... joins Blueprint from Algeta ASA, where he served on ... the acquisition by Bayer. Mr. Albers succeeds Alexis ... Partner at Third Rock Ventures, who will remain an ...
Breaking Medicine Technology:Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 2Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 3Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 4Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 5Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 2Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 3Blueprint Medicines Appoints Jeffrey Albers as Chief Executive Officer 2
... 2011 Volcano Corporation (NASDAQ: VOLC ), a ... designed to enhance the diagnosis and treatment of coronary and ... operating results for the third quarter of fiscal 2011 on ... conference call to discuss its financial results and operating activities ...
... Oct. 17, 2011 /PRNewswire-Asia/ -- China Botanic Pharmaceutical Inc. ... the "Company"), a developer, manufacturer and distributor of botanical ... today announced the results of its annual general meeting ... 2011 in Harbin, China. At the Annual ...
Cached Medicine Technology:Volcano Corporation Schedules Third Quarter Conference Call, Webcast 2China Botanic Announces Results of Annual General Meeting 2
Intended for the quantitative determination of direct bilirubin in serum. Modified EvelynMalloy Method. Endpoint Reaction. Wavelength: 555 nm. Linearity: 20 mg/dl (340 mol/l)...
... Powerwave is the first microplate spectrophotometer ... day, 7 days per week. With rugged ... footprint. Powerwave breaks the barrier of traditional ... reliably. One instrument can easily read up ...
Spectra 3000RS & Spectra 3000RSP are very precise instruments. They have a metal base structure, durable parts for long life use, and they are very easy to use and maintain....
... Series Spectrophotometer is truly ... UV-VIS instrumentation. The latest ... into a radically new ... and performance unprecedented in ...
Medicine Products: