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NCH investigators receive grant to distinguish bacterial infections from viral infections in infants
Date:9/30/2010

department with a fever. We think it will give physicians and families quicker and precise information, helping avoid unnecessary tests and hospitalizations."

Dr. Ramilo is leading the study along with Dr. Nathan Kuppermann of UC Davis Health System in Sacramento and Dr. Prashant Mahajan of Children's Hospital of Michigan and Wayne State University. They are collaborating with colleagues at medical centers around the country as part of the PECARN network. Also involved in the study are Bema Bonsu, MD, an attending physician in the Emergency Department at Nationwide Children's Hospital and Daniel Cohen, MD, an associate director of Emergency Medicine at Nationwide Children's Hospital within the Emergency Department at Nationwide Children's and Asuncion Mejias, MD, an investigator at the Center for Vaccines and Immunity in The Research Institute at Nationwide Children's Hospital within Infectious Diseases.

"Bacterial infections likely carry very distinct biological signatures because they induce different host responses than nonbacterial pathogens," said Dr. Mejias. "We plan to use a type of molecular fingerprint technology to enable physicians to identify the specific markers in bacterial infections, as well as determine if such tests are feasible and practical in the emergency room setting."

There is a need to develop less invasive, highly accurate and timelier diagnostic strategies for febrile infants. Making use of new molecular tools, especially in emergency care, could ultimately help improve care for the youngest of patients, added Dr. Ramilo.


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Contact: Erin Pope
Erin.Pope@NationwideChildrens.org
614-355-0495
Nationwide Children's Hospital
Source:Eurekalert

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