NCCAM expands Centers of Excellence in CAM resear...(s including antioxidants such as curcumi...),Health

Date:10/5/2007

s, including antioxidants such as curcumin (a component of the spice turmeric) and lycopene (the component that gives tomatoes their color), and preparations of green tea and Scutellaria baicalensis (a plant used in traditional Chinese medicine). Using animal models, the investigators will study the mechanisms and effects of these plant compounds on the prevention and/or treatment of pancreatic cancer and pancreatitis (inflammation of the pancreas).

• Center for CAM Research on Autoimmune and Inflammatory Diseases
  Principal Investigator: Prakash Nagarkatti, Ph.D.
  Institution: University of South Carolina Research Foundation, Columbia, SC

  This center will focus on the effects of plant and herbal products on preventing or arresting inflammation in diseases caused by immune system breakdown. Using an animal model, researchers will investigate the mechanisms by which resveratrol, a compound found in the skin of red grapes, might aid in the treatment of multiple sclerosis. The center will also examine anti-inflammatory mechanisms of the herb American ginseng in colitis and the actions of a compound from hemp in treating autoimmune hepatitis.

• Protective Roles of Grape-Derived Polyphenols in Alzheimers Disease
  Principal Investigator: Giulio Maria Pasinetti, M.D., Ph.D.
  Institution: Mount Sinai School of Medicine, New York, NY

  This center will conduct preclinical studies to identify natural compounds extracted from grapes, known as polyphenols that might have a protective role in Alzheimers disease. Using an animal model, the research team will then investigate the biological mechanisms by which these grape-derived compounds may affect changes in the brain that are characteristic of Alzheimers disease and associated with cognitive decline.

These center grants, which provide 5 years of support, bring the total number of Centers of Excellence for Research on CAM to
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Contact: NCCAM Press Office NCCAMPress@mail.nih.gov 301-496-7790 NIH/National Center for Complementary and Alternative Medicine Source:Eurekalert

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