Navigation Links
Mutated Suppressor Gene Leads to a Type of Breast Cancer
Date:12/10/2007

one of them will offer a cure, but the drugs in the right combination could lead to a cure.

The development of these drugs also may be important for other types of cancers that can involve deactivating the PTEN gene, Parsons said.

The study results were published online Dec. 9 in the journal Nature Genetics.

Parsons said the discovery of the PTEN deactivation "was kind of a real long-term detective story." For 10 years, researchers have been trying to understand how the mutation in the BRCA1 gene can cause breast cancer. Instead of using traditional gene-sequencing techniques, Parsons and his colleagues looked for physical breaks in the PTEN gene. "PTEN is actually physically broken in half, we estimate, in 30 to more than 50 percent of the BRCA1 tumors," he said.

Dr. Jeffrey Weitzel, an associate professor of medical oncology at the City of Hope Comprehensive Cancer Center in Duarte, Calif., said the study by Parsons' team "helps us understand what's under-appreciated in the complex nature of tumor changes."

Andrew Godwin, director of the clinical molecular genetics laboratory at the Fox Chase Cancer Center in Philadelphia, added: "As we move towards personalized health care [and] medicine, identifying the cadre of genetic defects in a given breast tumor will likely influence how that patient is ultimately treated."

More information

For more on breast cancer, visit the U.S. National Cancer Institute.



SOURCES: Andrew Godwin, Ph.D., director, Clinical Molecular Genetics Laboratory and the Biosample Repository, Fox Chase Cancer Center, Philadelphia; Ramon Parsons, M.D., Ph.D., director of the Breast Cancer Program of the Herbert Irving Comprehensive Cancer Center of Columbia University Medical Center and New York-Presbyterian Hospital, and professor of medicine and path
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Study details regulation of vital tumor suppressor gene p53
2. M. D. Anderson researchers identify tumor-suppressor gene for lung cancer
3. Removing Ovaries Before Menopause Leads to Memory, Movement Troubles
4. Lack of sleep among new school-goers leads to behavioral, cognitive problems
5. Olympic Gold Medalist Marion Jones-Thompson Pleads Guilty to Making False Statements in Two Separate Federal Criminal Investigations
6. AstraZeneca Leads Local Walking Movement
7. Leeza Gibbons Leads New Coaching Program to Boost the Nations Heart Health
8. Support System Leads to Better Diet, Nutrition
9. Brain atrophy in elderly leads to unintended racism, depression and problem gambling
10. Medical University of South Carolina Leads Multicenter Study Evaluating Biliary Sphincter Disorder
11. Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mutated Suppressor Gene Leads to a Type of Breast Cancer
(Date:7/31/2015)... ... ... Ticket Down is a reliable source for authentic tickets for the 2015 ... The festival will end on Sunday, August 2nd. , Music fans have ... This unique and unbelievably popular festival attracts the best in entertainment from around the ...
(Date:7/31/2015)... ... July 31, 2015 , ... Last week, the Mesothelioma Applied ... can be accessed by visiting http://www.curemeso.org/store . , “Our new store features ... part: whenever a product is purchased, the Meso Foundation receives a $5.00 donation,” ...
(Date:7/31/2015)... ... 31, 2015 , ... There’s no better way to enjoy the summer weather ... cook the next meal, making July the most appropriate to be National Hot Dog ... recipes. , Make the next cookout different than the ones in the past. Celebrate ...
(Date:7/31/2015)... ... ... Coco Libre announced today that their flagship Organic Coconut Water will be ... Open of Surfing, July 25 through August 2 in Huntington Beach, California. Coco Libre, ... is a natural choice given the Open’s commitment to sustainable practices. , Designated ...
(Date:7/31/2015)... ... 31, 2015 , ... According to the article published July 27 on My News ... contained and extinguished by the city’s fire department before it caused major damage throughout the ... of the fire, and it was a fire alarm system that tipped off fire fighters ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:Mesothelioma Organization Launches New Store 2Health News:Mesothelioma Organization Launches New Store 3Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3
... Important During May,s tribute to Older Americans, Nursing ... 11 CareOne, New Jersey,s largest family-owned and ... hotel-like Centers, and the use of computer technology ... patients compared to national averages.Independent research data demonstrate ...
... SMBL) will hold its annual meeting of stockholders at 10 ... Julien Hotel (Fandango Room), 900 Walnut Street, Boulder, Colorado, 80302. ... April 1, 2009, are entitled to attend and vote on ... Smart Balance, Inc. , Smart Balance, Inc. (NasdaqGM: SMBL) ...
... of organizations from more than 16 countries will hold a Global Day ... immediately release Kamiar and Arash Alaei. , ... (Vocus) May 11, 2009 ... Roxana Saberi, there is still continuing vigilance over the unjust imprisonments of ...
... May 11 Karen Ignagni, President and CEO of ... on the cost containment framework presented to President Obama:"Health ... help advance a framework for cost containment, which is ... families and purchasers and preserve the competitiveness of our ...
... CHICAGO, May 11 Harris announced today that it ... response to prevent the spread of H1N1 and other ... fund the hand sanitizing gel at more than 400 ... Midway Airport."As Chicago,s hometown bank, we applaud our Mayor, ...
... the University of Queensland in Australia have found a traditional ... to be safe and effective in reducing anxiety. , To ... Psychopharmacology , the results of a world-first clinical trial which ... treating anxiety and improving mood. The Kava was prescribed in ...
Cached Medicine News:Health News:State-of-the-Art Technology and Hotel-Like Environment Get CareOne's Rehab Patients Home Quicker 2Health News:State-of-the-Art Technology and Hotel-Like Environment Get CareOne's Rehab Patients Home Quicker 3Health News:Saberi Release Highlights Case of Imprisoned Iranian AIDS Doctors 2Health News:Saberi Release Highlights Case of Imprisoned Iranian AIDS Doctors 3Health News:AHIP Statement on Cost Containment Framework 2Health News:Harris Joins City of Chicago in Support of Maintaining Good Health Habits 2Health News:Research finds kava safe and effective 2
(Date:7/30/2015)... July 30, 2015  Unichem Pharmaceuticals ( USA ... of Hydrochlorothiazide tablets 25 mg 1000-count bottle to the ... precautionary measure due to the identification of a Clopidogrel ... The risk associated with mistakenly taking a ... increased probability of experiencing Clopidogrel,s side effects which include ...
(Date:7/30/2015)... , July 30, 2015  Amgen (NASDAQ: AMGN ) ... and managing director of Warburg Pincus LLC, to the Amgen ... welcome Fred Hassan and the deep, global experience ... said Robert A. Bradway , chairman and chief executive ... innovation will serve Amgen well." Mr. Hassan has ...
(Date:7/30/2015)... N.J. , July 30, 2015  Growth of ... switches as they bring former prescription users to the ... Kline forecasts robust Rx-to-OTC switch activity over ... categories emerging along with many new brands entering the ... occur over the next five years (even those with ...
Breaking Medicine Technology:Unichem Pharmaceuticals (USA), Inc. Issues a Voluntary Nationwide Recall of Hydrochlorothiazide Tablets Due to the Potential Presence of Foreign Tablets 2Amgen Announces Appointment Of Fred Hassan To Board Of Directors 2Amgen Announces Appointment Of Fred Hassan To Board Of Directors 3Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 3
... brand drug "copay coupon" promotions, which lure insured consumers ... by $681 million in Missouri over the next decade ... new research from Visante and released by the ... these promotions by state and local government workers alone ...
... The proliferation of brand drug "copay coupon" promotions, ... brands, will increase costs by $1.1 billion in Michigan ... employee plans, according to new research from Visante and ...  The use of these promotions by state and ...
Cached Medicine Technology:Brand Drug 'Copay Coupons' Undermine Generics, Raise Health Costs by $681 Million in Missouri 2Brand Drug 'Copay Coupons' Undermine Generics, Raise Health Costs by $1.1 Billion in Michigan 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: