Navigation Links
Muscle Mass May Not Explain High Creatinine in Black Kidney Patients
Date:4/18/2008

Findings challenge belief that racial disparities were result of age, body composition

FRIDAY, April 18 (HealthDay News) -- Differences in muscle mass related to younger age or body composition may not explain why black patients with advanced kidney disease have higher levels of creatinine than white patients, says a U.S. study that challenges a widely held belief.

Creatinine is a standard indicator of kidney function. A higher level of creatinine is generally a sign of lower kidney function.

In this study, researchers at the University of California, San Francisco School of Medicine examined serum creatinine concentrations and body composition in more than 3,000 kidney dialysis patients. As expected, blacks had higher creatinine levels than non-black patients.

"A widely assumed explanation for this racial difference is that black patients tend to develop end-stage kidney disease earlier than whites. So blacks on dialysis tend to be younger than whites and persons of other races and ethnicities and so may have more muscle mass, and creatinine is a natural breakdown product of muscle," study leader Dr. Joy Hsu said in a prepared statement.

To test this theory, Hsu and colleagues used something called bioelectrical impedance analysis to estimate the patient's muscle mass.

"We hypothesized that adjusting for muscle mass and related factors would eliminate or reduce the racial differences in serum creatinine levels," Hsu said.

However, even after making that adjustment, black patients had significantly higher creatinine levels.

"The higher creatinine levels in black patients compared to non-black patients could not be entirely explained by differences in age, sex, body size, or muscle mass," Hsu said.

The study was published online in the Clinical Journal of the American Society of Nephrology and is expected to be published in the July print edition of the journal.

More research is needed to uncover why black patients with kidney disease have higher creatinine levels than other patients. The "answer or answers to this question may help explain why blacks are affected by progressive chronic kidney disease more so than whites," Hsu said.

More information

The U.S. National Kidney Disease Education Program has more about kidney disease.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, April 16, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. New treatment boosts muscle function in myasthenia gravis
3. New Drug Aids Muscle Function in Myasthenia Gravis
4. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
5. Muscle patterns in women may be linked to at risk positioning for ACL tears
6. Endoscopic resection is a safe and effective treatment for gastrointestinal smooth muscle tumors
7. Study reveals how stem cells decide to become either skeletal or smooth muscle
8. Pre-Workout Stretching Wont Prevent Sore Muscles
9. Steroids Are Abused for Skin, Not Just Muscles
10. AUA releases new guidelines on non-muscle invasive bladder cancer
11. Scientists identify gene responsible for statin-induced muscle pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/18/2017)... ... February 17, 2017 , ... Park Cities Pet Sitter President, Joette White, ... Pet Life Radio network. The episode, which was posted this week, features a ... factors led to Park Cities Pet Sitter’s being awarded the 2017 National Association of ...
(Date:2/17/2017)... NC (PRWEB) , ... February 17, 2017 , ... Smiles ... Commons Shopping Center in Davidson, NC. Dr. Brian Seese leads the practice as a ... dental services under one roof. Smiles by Seese serves patients of all ages with ...
(Date:2/17/2017)... ... February 17, 2017 , ... Wells Pharmacy Network offers ... of controlled and non-controlled substances plus the ability to manage orders on their ... States now accept electronic prescriptions, according to the Office of the National Coordinator ...
(Date:2/17/2017)... Palos Verdes, CA (PRWEB) , ... February 17, ... ... and emotional flow is Dr. Carol Francis' goals for each and ... Retreat Conference, Dr. Carol Francis will demonstrate five different brainwave tools which help ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... HIMSS17 Conference & Exhibition in Orlando, Fla., February 19-23. Visitors to the company’s ... most widely used electronic patient signatures solution in healthcare . , ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... -- On Thursday, February 16, 2017, the ... the closing bell, while the Dow Jones Industrial Average ... five out of nine sectors ended Thursday,s trading session ... Stock-Callers.com assessed the following Medical Appliances & Equipment equities ... SNN ), ABIOMED Inc. (NASDAQ: ABMD ), ...
(Date:2/16/2017)... EXTON, Pa. , Feb. 16, 2017 ... drugs, biologics, and medical devices, is pleased to announce ... Ph.D., has been selected as a winner of the ... SmartCEO Magazine and recognizes driven executives for ... undeniable work ethic. The awards ceremony and celebration is ...
(Date:2/16/2017)... , Feb. 16, 2017 Quest Diagnostics (NYSE: ... diagnostic information services, today announced that it has been ... 2017 by Fortune. The annual survey ... in the "Health Care: Pharmacy and Other Services" industry ... information services company to attain the designation. This is ...
Breaking Medicine Technology: