Navigation Links
Multivitamin use doesn't impact colon cancer outcomes
Date:9/7/2010

BOSTON--Patients with colon cancer who used multivitamins during and after being treated with post-surgical chemotherapy did not reduce the risk of the cancer returning or their dying from it, according to researchers at Dana-Farber Cancer Institute.

In a study of patients with stage III colon cancer characterized as cancer in the large bowel area with some cancer cells in a few nearby lymph nodes -- the researchers found that while multivitamin use had no beneficial effect on patients' outcomes, it also did not have a detrimental effect. The findings are reported online in the Journal of Clinical Oncology and later will be published in a print edition.

Kimmie Ng, MD, MPH, the paper's first author and a gastrointestinal oncologist at Dana-Farber, said that despite conflicting evidence on the efficacy of multivitamins to reduce cancer risk and death, studies suggest that approximately 30 percent of Americans take multivitamins to prevent and treat chronic diseases such as cancer. Among cancer survivors, between 26 and 77 percent report using multivitamins.

"With such a high proportion of cancer patients utilizing multivitamin supplements in the belief that it will help them fight their cancer, we felt it was important to really examine the data to see what impact multivitamins had on cancer recurrence and survival," said Ng.

The researchers used two questionnaires to track multivitamin use during and after chemotherapy. Of the 1,038 patients who completed the first survey, nearly half (518) responded they used multivitamins while receiving chemotherapy. Of the 810 cancer-free patients who completed the second survey six months after chemotherapy, more than half (416) reported multivitamin use.

Ng and her colleagues found no statistically significant differences in the rates of disease-free survival (the study's primary endpoint), recurrence-free survival, or overall survival between those who used multivitamins and those who didn't.

They also determined that an array of factors, including socio-economic status, household income, multivitamin and individual vitamin dosage, and consistency of multivitamin use did not impact their findings.

However, they did find a small beneficial association between age and weight and the use of multivitamins while receiving chemotherapy. Those 60 and younger experienced some survival benefit, as did obese patients. There were no benefits for either subgroup when the multivitamins were taken after chemotherapy was completed. Ng said additional studies are needed to confirm their findings and to investigate whether there were other factors that influenced the outcomes.

"This study adds to a growing body of research that questions the purported benefit of multivitamin use, and it underscores the need to investigate the use of individual vitamins, such as vitamin D, which may, in fact, provide real benefit," said Charles Fuchs, MD, director of gastrointestinal oncology at Dana-Farber and the paper's senior author. He noted that the average multivitamin typically contains only a small to modest amount of vitamin D.


'/>"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
Source:Eurekalert  

Related medicine news :

1. New Multivitamins Target Concern Over China's Quality Problems
2. Announcing NutriVite, Liquid Multivitamin Shots - Welcome to the Future of Vitamins
3. 2010 HSR Impact Award recognizes surgical safety research
4. New Research Examines Impact of Health Care Reform on Regional Health Plans
5. Local Blood Supply Impacted by Wednesdays Severe Snow Storm
6. Mayo Clinic responsible for $22 billion in economic impact, including $9.6 billion in Minnesota
7. Bersin & Associates Unveils Agenda for Research Conference, IMPACT 2010: The Business of Talent(R)
8. New research shows emotional impact of low sexual desire and associated distress
9. Pay-for-performance programs show positive impact on low-performing physicians
10. How health care is paid for appears to impact outcome
11. California to Examine Health Impacts of Landmark Cap-and-Trade Program
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Multivitamin use doesn't impact colon cancer outcomes
(Date:12/6/2016)... , ... December 06, 2016 , ... TopConsumerReviews.com recently gave ... Mobility Scooters . , Mobility Scooters give freedom to people who need help getting ... others may be facing a long period of rehabilitation after an illness or accident. ...
(Date:12/5/2016)... ... 2016 , ... What: Shriners Hospitals for Children, with the help of Dimension ... using a video monitor and web-enabled camera. Santa visits with children through Dimension Data’s ... Christmas Wonderland, which is where the video connection to the North Pole will stream. ...
(Date:12/5/2016)... (PRWEB) , ... December 06, 2016 , ... For many ... Lithuanian poetry , both thick and thin. The beauty of the Lithuanian language ... Trafford Publishing). , In this poetry book, Zubinas lyrically explores all aspects of a ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... leading global lifestyle design firm kathy ireland® Worldwide for five additional years, announced ... entered into an exclusive licensing agreement three years ago to design and develop ...
(Date:12/5/2016)... (PRWEB) , ... December 05, ... ... strategic interoperability, today announced that the company will provide alerting technology to ... has been recently awarded $1.7 million in federal funds as the sole ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... Fla. , Dec. 5, 2016  Breckenridge ... into a multi-product marketing agreement with development and ... injectable products. Under the terms of this agreement, ... its label in the United States ... and one tentatively-approved ANDA. The products cover a ...
(Date:12/5/2016)... , December 5, 2016 According to a new ... and by Application - Global Opportunity Analysis and Industry Forecast, 2014 - 2022", ... expected to reach $5,255 million by 2022, growing at a CAGR of 6.4% ... more than four-fifths share. Continue Reading ... ...
(Date:12/5/2016)... Sanovas, Inc., a life science asset holding company ... wholly owned subsidiary, Intubation Science, Inc., and its LightSpeed Intubation ... http://photos.prnewswire.com/prnh/20161202/445251LOGO   ... Sanovas, Inc. ... There are over 40 million Endotracheal Intubations performed annually ...
Breaking Medicine Technology: