Navigation Links
Multivitamin use doesn't impact colon cancer outcomes
Date:9/7/2010

BOSTON--Patients with colon cancer who used multivitamins during and after being treated with post-surgical chemotherapy did not reduce the risk of the cancer returning or their dying from it, according to researchers at Dana-Farber Cancer Institute.

In a study of patients with stage III colon cancer characterized as cancer in the large bowel area with some cancer cells in a few nearby lymph nodes -- the researchers found that while multivitamin use had no beneficial effect on patients' outcomes, it also did not have a detrimental effect. The findings are reported online in the Journal of Clinical Oncology and later will be published in a print edition.

Kimmie Ng, MD, MPH, the paper's first author and a gastrointestinal oncologist at Dana-Farber, said that despite conflicting evidence on the efficacy of multivitamins to reduce cancer risk and death, studies suggest that approximately 30 percent of Americans take multivitamins to prevent and treat chronic diseases such as cancer. Among cancer survivors, between 26 and 77 percent report using multivitamins.

"With such a high proportion of cancer patients utilizing multivitamin supplements in the belief that it will help them fight their cancer, we felt it was important to really examine the data to see what impact multivitamins had on cancer recurrence and survival," said Ng.

The researchers used two questionnaires to track multivitamin use during and after chemotherapy. Of the 1,038 patients who completed the first survey, nearly half (518) responded they used multivitamins while receiving chemotherapy. Of the 810 cancer-free patients who completed the second survey six months after chemotherapy, more than half (416) reported multivitamin use.

Ng and her colleagues found no statistically significant differences in the rates of disease-free survival (the study's primary endpoint), recurrence-free survival, or overall survival between those who used multivitamins and those who didn't.

They also determined that an array of factors, including socio-economic status, household income, multivitamin and individual vitamin dosage, and consistency of multivitamin use did not impact their findings.

However, they did find a small beneficial association between age and weight and the use of multivitamins while receiving chemotherapy. Those 60 and younger experienced some survival benefit, as did obese patients. There were no benefits for either subgroup when the multivitamins were taken after chemotherapy was completed. Ng said additional studies are needed to confirm their findings and to investigate whether there were other factors that influenced the outcomes.

"This study adds to a growing body of research that questions the purported benefit of multivitamin use, and it underscores the need to investigate the use of individual vitamins, such as vitamin D, which may, in fact, provide real benefit," said Charles Fuchs, MD, director of gastrointestinal oncology at Dana-Farber and the paper's senior author. He noted that the average multivitamin typically contains only a small to modest amount of vitamin D.


'/>"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
Source:Eurekalert  

Related medicine news :

1. New Multivitamins Target Concern Over China's Quality Problems
2. Announcing NutriVite, Liquid Multivitamin Shots - Welcome to the Future of Vitamins
3. 2010 HSR Impact Award recognizes surgical safety research
4. New Research Examines Impact of Health Care Reform on Regional Health Plans
5. Local Blood Supply Impacted by Wednesdays Severe Snow Storm
6. Mayo Clinic responsible for $22 billion in economic impact, including $9.6 billion in Minnesota
7. Bersin & Associates Unveils Agenda for Research Conference, IMPACT 2010: The Business of Talent(R)
8. New research shows emotional impact of low sexual desire and associated distress
9. Pay-for-performance programs show positive impact on low-performing physicians
10. How health care is paid for appears to impact outcome
11. California to Examine Health Impacts of Landmark Cap-and-Trade Program
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Multivitamin use doesn't impact colon cancer outcomes
(Date:5/29/2016)... ... 29, 2016 , ... "With 30 unique self-animating web themed intros and complete ... their project," said Christina Austin - CEO of Pixel Film Studios. , ProIntro ... use in Final Cut Pro X. Pixel Film Studios’ minimalistic titles allow users to ...
(Date:5/28/2016)... (PRWEB) , ... May 28, 2016 , ... "Color Grading ... drag and drop a preset onto their media," said Christina Austin - CEO of ... Studios, editors can quickly and easily add stylish color grades to their footage. A ...
(Date:5/28/2016)... , ... May 28, 2016 , ... After a year and a half of planning ... an extraordinary event. The Multiple Pathways of Recovery Conference was held May 2 -4, ... country and the United Kingdom came together to explore the many pathways individuals use to ...
(Date:5/27/2016)... ... 27, 2016 , ... More than a third of American adults are considered ... surgery has received increased attention in recent years, as an article published ... weight loss, most people are familiar with the basic requirements of maintaining a healthy ...
(Date:5/27/2016)... ... ... Two director-level employees of Horizon Blue Cross Blue Shield of New Jersey ... The award recognizes businesswomen who excel in their fields and who have made ... (Managed Long-Term Services and Supports) Program at Horizon NJ Health and Theresa Ponton, Director ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... Israel , May 31, 2016 ... its proprietary plant-based rhCollagen technology for tissue repair products ... Chief Scientist of Israel,s Ministry ... 12 million development project for 2016. The Chief Scientist,s grant ... year,s authorized grant, which totaled NIS 4.7 million.  ...
(Date:5/31/2016)... LONDON , May 31, 2016 ... der World Health Assembly zur Eliminierung von viraler ... 194 Mitgliedsstaaten eine historische Verpflichtung eingegangen, virale Hepatitis ... 69 . World Health Assembly haben sich ... Strategie bzgl. viraler Hepatitis (Global Viral Hepatitis Strategy) ...
(Date:5/30/2016)... May 30, 2016 Transparency Market ... (3D/4D) Visualization Systems Market - Global Industry Analysis, Size, ... to the report, the global advanced (3D/4D) visualization systems ... and is anticipated to expand at a CAGR of ... Bn in 2024. Advanced (3D/4D) visualization systems ...
Breaking Medicine Technology: