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Multiple sclerosis will become a controlled disease like AIDS
Date:10/28/2010

The complexity of the immune system and nervous system turn Neuroimmunology into one of the most exciting fields of modern biomedicine. Between October 26th and 30th takes place in Sitges (Barcelona, Spain) the X International Congress of Neuroimmunology of the International Society of Neuroimmunology. This event highlights the advances that have been made in recent years thanks to new technologies, but also highlights the long road ahead. New biomarkers, potential immunotherapies, stem cell strategies and new discoveries about the natural history of neuroimmunological diseases are some of the issues that focus the attention of the 1,000 scientists attending the Congress.

Multiple Sclerosis is one of the most well known study area of Neuroimmunology. This autoimmune disease causes demyelination of neurons that leads to a neurodegenerative process. Recent studies of association with whole genome data have identified about 20 genes associated with susceptibility to develop the disease. Scientific community estimates that in the next 2 years there will be around 80 associated genes that will make a very accurate picture of the disease genetic basis. Systems biology, which uses computer models to analyze complex biological processes, complements these studies integrating genetic, molecular, physiological and clinical information.

The tools of high-throughput sequencing and genotyping, along with innovative brain imaging techniques that improve phenotypic characterization of the disease, combine to further define the set of involved genes. Neuroinflammation and the mediators that cause neuronal demyelination are two processes gaining interest in research. Already available drugs are being successful in the fight against neuroinflammation, and many scientists believe that when the disease is diagnosed at an early stage it will soon become a controlled disease, as has been achieved with AIDS.

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Contact: lex Argem
aargemi@clinic.ub.es
34-932-275-700
IDIBAPS - Institut d'Investigacions Biomdiques August Pi i Sunyer
Source:Eurekalert

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