Navigation Links
Multiple sclerosis: New marker could improve diagnosis
Date:7/12/2012

For the first time, scientists in Germany's multiple sclerosis competence network have been able to identify an antibody that bonds with the potassium channel KIR4.1. "We found this autoantibody in almost half of the MS patients in our study," explains Bernhard Hemmer, Professor of Neurology at the Klinikum rechts der Isar hospital at Technische Universitaet Muenchen (TUM). The biomarker was not present in healthy patients. The findings could therefore indicate that KIR4.1 is one of the targets of the autoimmune response in MS. Humans and animals without the KIR4.1 channel experience neurological failure and cannot coordinate their movements properly. Furthermore, their bodies do not create sufficient amounts of myelin, a layer of insulation that protects the nerve cells.

KIR4.1 is primarily present in the membrane of glial cells, which are responsible for controlling metabolism in the brain and forming myelin. The neurologists will now be conducting follow-up studies into how KIR4.1 antibodies influence the development of MS. This autoantibody is extremely rare in people with other neurological diseases, making it an important potential diagnostic marker for MS in the future. "This autoantibody could improve diagnosis of MS and help us differentiate it more clearly from other neurological diseases," continues Hemmer. This will also be the focus of further research.


'/>"/>
Contact: Barbara Wankerl
wankerl@zv.tum.de
49-892-892-2562
Technische Universitaet Muenchen
Source:Eurekalert  

Page: 1

Related medicine news :

1. Researchers developing new multiple sclerosis drug that can be taken orally
2. Botox May Ease Tremors in Multiple Sclerosis Patients
3. Intensive cholesterol therapy with multiple drugs effective over long term
4. Stopping and starting cancer cell cycle weakens and defeats multiple myeloma
5. Multiple sclerosis patients have lower risk of cancer: UBC-VCH research
6. Lenalidomide prolongs disease control for multiple myeloma patients after stem cell transplant
7. Pot Might Help Ease Multiple Sclerosis Symptoms
8. FDA Issues Multiple Sclerosis Drug Alert
9. Study shows benefit of new maintenance therapy for multiple myeloma
10. Multiple thought channels may help brain avoid traffic jams
11. Low-dose whole-body CT finds disease missed on standard imaging for patients with multiple myeloma
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Multiple sclerosis: New marker could improve diagnosis
(Date:5/26/2017)... ... 26, 2017 , ... via seating is proud to partner ... chair specifically designed for clinical areas. Genie Copper Mesh is a crossover chair ... to provide customers with a game changing chair that is affordably priced,” Chas ...
(Date:5/26/2017)... ... May 26, 2017 , ... After raising nearly $30,000 on ... continue to be available at a discounted crowdfunding price on Indiegogo . , ... are, I also wanted to bring a fidget toy to the market that was ...
(Date:5/26/2017)... ... ... Silver Birch of Hammond, a new assisted lifestyle community, has welcomed its first ... at 5620 Sohl Avenue in Hammond, serves older adults who need some help to ... apartments. Each of the private apartments at Silver Birch features a kitchenette, spacious bathroom ...
(Date:5/26/2017)... ... , ... Dr. Alex Rabinovich, a highly-skilled oral surgeon specializing in wisdom teeth ... insurance options. If a Bay Area patient has to search for a second opinion ... an in-network provider for a second opinion can ensure a patient receives the full ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “THE FLINTHILLS FAMILY-Our Journey to the Cross”: the ... Journey to the Cross” is the creation of published authors, Bob and Margaret Massey. ... to say, he is "panther quick and leather tough." His love for others is ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)...   BioLife Solutions , Inc. (NASDAQ: ... proprietary clinical grade hypothermic storage and ... announced that the Company,s first quarter 2017 financial results ... 11, 2017, and that the Company will host a ... that afternoon. Management will provide an overview of the ...
(Date:5/3/2017)... ROCKVILLE, Md. , May 3, 2017 /PRNewswire/ ... revenue growth of nine percent next year and ... solid organ and hematopoietic stem cell (HSCT) or ... and donor. Molecular testing technologies are well-suited for this ... healthcare-only market research publisher Kalorama Information. The various ...
(Date:5/3/2017)... 2017  West Pharmaceutical Services, Inc. (NYSE: WST), ... drug administration, announced today that Fran DeGrazio ... and Diane Paskiet , Director, Scientific Affairs, ... on West,s expertise in the areas of safety ... providing commentary on updated industry guidance. ...
Breaking Medicine Technology: