Navigation Links
Multiple malaria vaccine offers protection to people most at risk
Date:10/26/2011

A new malaria vaccine could be the first to tackle different forms of the disease and help those most vulnerable to infection, a study suggests.

The new vaccine is designed to trigger production of a range of antibodies to fight the many different types of parasite causing the disease.

Scientists created the vaccine by combining multiple versions of a key protein found in many types of malaria parasite, which is known to trigger production of antibodies upon infection.

Mixing multiple proteins from various parasite types induces antibodies against a wide range of the parasites causing the disease.

Researchers from the University of Edinburgh, who developed the vaccine, say that because malaria parasites exist in many forms, the only way to gain natural immunity against all strains is by having multiple bouts of the illness. A vaccine that overcomes this could be especially useful in children and other vulnerable groups of people.

Many previous vaccines against malaria have had limited success because they target only a limited part of the parasite population. The new vaccine has also shown to be effective in animals.

Tests in blood samples from children in endemic areas showed that the antibodies against this key protein offered improved protection against the disease. Scientists now hope to carry out full-scale human trials.

Malaria is spread by mosquito bites and affects people and animals, mostly in sub-Saharan Africa. According to the World Health Organisation, in 2009 the disease affected 225 million people and caused an estimated 781,000 deaths, mostly among African children.

The study, published in PLoS One, was supported by the European Commission.

Dr David Cavanagh, of the University of Edinburgh's School of Biological Sciences, who led the study, said: "Our approach is novel because it combines multiple antibody targets from different parasite types, giving broader protection. This could prove to be a useful vaccine."


'/>"/>
Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh
Source:Eurekalert

Related medicine news :

1. More African-Americans burdened by osteoarthritis in multiple large joints
2. New drug strategies for Alzheimers, multiple sclerosis examined at UH
3. Shift work in teens linked to increased multiple sclerosis risk
4. Shift Work May Put Teens at Risk for Multiple Sclerosis
5. Mayo Clinic study: multiple surgeries and anesthesia exposure
6. MRI research demonstrates ALS attacks multiple parts of the brain
7. Moffitt Cancer Center researchers use new tool to counter multiple myeloma drug resistance
8. Starving inflammatory immune cells slows damage caused by multiple sclerosis
9. A patients own skin cells may one day treat multiple diseases
10. Childhood cancer survivors are at high risk for multiple tumors as they age
11. Study finds pregnancy safe in multiple sclerosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “The Journey: ... faced every danger possible to save lost souls in the Philippines. “The Journey: From ... Carole is a dedicated teacher of the Bible. She has taught all ages and ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the Los ... article to the newly revamped Cosmetic Town journal section, featuring articles ... procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi says ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... CAESAREA, Israel and NEW YORK , Sept. ... company with mobile health and big data solutions, today announced that its ... today. Please check your local TV listings for when The Dr. Oz ... ... ninth season this month. ...
(Date:9/25/2017)...  EpiVax, Inc., a leader in the fields ... announced the launch of EpiVax Oncology Inc., a ... cancer vaccines. EpiVax has provided $500,000 in seed ... technologies to the new precision immunotherapy venture. Gad ... as Chief Executive Officer. Gad brings over 25 ...
(Date:9/22/2017)... , Sept. 22, 2017  As the latest Obamacare ... Bill Cassidy (R-LA) and Lindsey Graham ... that the medical device industry is in an odd ... tax, the 2.3% excise tax on medical device sales ... also want covered patients, increased visits and hospital customers ...
Breaking Medicine Technology: