Navigation Links
Multiple malaria vaccine offers protection to people most at risk
Date:10/26/2011

A new malaria vaccine could be the first to tackle different forms of the disease and help those most vulnerable to infection, a study suggests.

The new vaccine is designed to trigger production of a range of antibodies to fight the many different types of parasite causing the disease.

Scientists created the vaccine by combining multiple versions of a key protein found in many types of malaria parasite, which is known to trigger production of antibodies upon infection.

Mixing multiple proteins from various parasite types induces antibodies against a wide range of the parasites causing the disease.

Researchers from the University of Edinburgh, who developed the vaccine, say that because malaria parasites exist in many forms, the only way to gain natural immunity against all strains is by having multiple bouts of the illness. A vaccine that overcomes this could be especially useful in children and other vulnerable groups of people.

Many previous vaccines against malaria have had limited success because they target only a limited part of the parasite population. The new vaccine has also shown to be effective in animals.

Tests in blood samples from children in endemic areas showed that the antibodies against this key protein offered improved protection against the disease. Scientists now hope to carry out full-scale human trials.

Malaria is spread by mosquito bites and affects people and animals, mostly in sub-Saharan Africa. According to the World Health Organisation, in 2009 the disease affected 225 million people and caused an estimated 781,000 deaths, mostly among African children.

The study, published in PLoS One, was supported by the European Commission.

Dr David Cavanagh, of the University of Edinburgh's School of Biological Sciences, who led the study, said: "Our approach is novel because it combines multiple antibody targets from different parasite types, giving broader protection. This could prove to be a useful vaccine."


'/>"/>
Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh
Source:Eurekalert

Related medicine news :

1. More African-Americans burdened by osteoarthritis in multiple large joints
2. New drug strategies for Alzheimers, multiple sclerosis examined at UH
3. Shift work in teens linked to increased multiple sclerosis risk
4. Shift Work May Put Teens at Risk for Multiple Sclerosis
5. Mayo Clinic study: multiple surgeries and anesthesia exposure
6. MRI research demonstrates ALS attacks multiple parts of the brain
7. Moffitt Cancer Center researchers use new tool to counter multiple myeloma drug resistance
8. Starving inflammatory immune cells slows damage caused by multiple sclerosis
9. A patients own skin cells may one day treat multiple diseases
10. Childhood cancer survivors are at high risk for multiple tumors as they age
11. Study finds pregnancy safe in multiple sclerosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... ... Johns Hopkins All Children's Hospital celebrated a major milestone with the topping ... the halfway point of construction and lifting of the final beam on the top ... center for innovation aimed at finding new discoveries and treatments for childhood diseases. The ...
(Date:2/19/2017)... ... February 19, 2017 , ... The Citadel’s new ... students, is being led by Amelia Joseph, Ph.D. Joseph was engaged by the college ... the nursing department in early 2016. After a nation-wide search, she was selected to ...
(Date:2/19/2017)... ... 19, 2017 , ... Orbita, Inc., a leading ... Healthwise ® at HIMSS 2017 to showcase a breakthrough in ... education, technology and services, will demonstrate a voice-powered knowedge assistant based on ...
(Date:2/18/2017)... , ... February 17, 2017 , ... ... drvallecillos.com , Beverly Hills plastic surgeon Dr. Glenn Vallecillos ... , Dr. Vallecillos says, "Traditionally, plastic surgery has been centered around that idea ...
(Date:2/17/2017)... ... 2017 , ... Smiles by Seese is a comprehensive family dental practice ... leads the practice as a skilled and highly credentialed dentist who is qualified to ... patients of all ages with excellence in general, restorative, and cosmetic dentistry . ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... 2017 Adequate intake of vitamin ... minerals in one,s body. Consumers are well aware of ... a healthy composition of bones and teeth. Consumption of ... growing in the world. Medical research and clinical trials ... for treatment of prevalent disorders such as multiple sclerosis, ...
(Date:2/19/2017)...   AC Group Inc. , a leading company, ... in the PMS/EHR healthcare marketplace, will exhibit the 7 ... succeed in this ecosystem at HIMSS,17. ... from over 200 ACOs, compared and analyzed an ACO,s ... that are providing different pieces of Population Health technologies ...
(Date:2/19/2017)... , February 18, 2017 Marapharm ... to purchase a Medical Delivery Service with the specific ... transactions between qualified patients and caregivers. The delivery service ... located in the Coachella Valley, California ... Los Angeles area to the West, population ...
Breaking Medicine Technology: